Gene Information

Name : pK2044_00635 (pK2044_00635)
Accession : YP_001687957.1
Strain :
Genome accession: NC_006625
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional activator CusR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 104079 - 104759 bp
Length : 681 bp
Strand : +
Note : response regulator in two-component regulatory system with CusS; regulates the copper efflux system

DNA sequence : 
ATGAAAATATTGATCGTCGAAGACGAAATTAAAACAGGTGAATATCTCAGCAAAGGGCTGACAGAGGCAGGGTTCGTCGT
GGATCACGCTGATAATGGTCTTACCGGATATCATCTCGCCATGACAGCCGAGTATGATTTAGTCATTCTGGATATCATGC
TACCTGATGTGAACGGCTGGGATATCATCCGCATGCTGCGCACTGCCGGAAAGGGTATGCCGGTCTTACTGCTGACGGCC
CTCGGCACGATCGAACACAGGGTCAAAGGACTGGAACTGGGTGCGGACGATTATCTGGTTAAACCCTTTGCGTTTGCCGA
ACTGCTCGCCCGGGTGAGAACCCTTCTGAGGCGGGGAAACACGATGATCACGGAAAGCCAGTTTAGGGTGGCTGATCTCT
CGATGGATCTCGTATCCAGAAAAGTCAGTCGCGCCGGAAACCGCATTGTGCTCACCAGTAAAGAGTTCAGCCTGCTGGAA
TTCTTCATTCGCCATCAGGGCGAGGTTCTTCCCCGCTCCCTGATTGCCTCTCAGGTCTGGGACATGAATTTTGACAGCGA
CACTAACGCGATTGATGTCGCCGTAAAGCGACTCCGCGCTAAAATAGACAACGATTACGGGACAAAGCTGATCCAGACTG
TCCGGGGCGTGGGCTATATACTGGAGGCCCCGGATGCATAG

Protein sequence : 
MKILIVEDEIKTGEYLSKGLTEAGFVVDHADNGLTGYHLAMTAEYDLVILDIMLPDVNGWDIIRMLRTAGKGMPVLLLTA
LGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGNTMITESQFRVADLSMDLVSRKVSRAGNRIVLTSKEFSLLE
FFIRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRAKIDNDYGTKLIQTVRGVGYILEAPDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-55 55
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 5e-55 54

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR BAC0347 Protein 7e-94 93
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR BAC0111 Protein 5e-94 86
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR BAC0638 Protein 6e-64 62
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR BAC0083 Protein 5e-70 61
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR BAC0197 Protein 3e-65 60
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR BAC0308 Protein 2e-61 58
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR BAC0125 Protein 7e-64 56
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR HE999704.1.gene1202. Protein 4e-36 41
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR AE000516.2.gene3505. Protein 1e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR VFG0596 Protein 6e-56 55
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR VFG1390 Protein 1e-42 43
pK2044_00635 YP_001687957.1 DNA-binding transcriptional activator CusR VFG1389 Protein 6e-34 41