Gene Information

Name : TK2158 (TK2158)
Accession : YP_184571.1
Strain : Thermococcus kodakaraensis KOD1
Genome accession: NC_006624
Putative virulence/resistance : Unknown
Product : carbamate kinase-like carbamoyl phosphate synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0549
EC number : -
Position : 1936252 - 1937199 bp
Length : 948 bp
Strand : -
Note : this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable react

DNA sequence :
ATGAAGAGAGTTGTCATAGCCTTGGGCGGGAACGCCATACTCCAGCGAGGCCAGAAGGGGACTTACGAGGAGCAGATGGA
GAACGTGAGGAGGACTGCCAAGCAGATCGCTGACATAATCCTTGACGGCGATTATGAAGTCGTTATCACCCACGGAAACG
GTCCACAGGTTGGTGCGCTCCTTCTCCACATGGACGCTGGCCAGCAGGTCTACGGCATCCCAGCCCAGCCTATGGACGTC
GCTGGAGCGATGACCCAGGGGCAGATAGGCTACATGATCGGCCAGGCGCTCATAAACGAGCTTAGGAAGAGAGGGGTCGA
GAAGCCCGTCGCAACGATAGTAACCCAGACCATCGTTGACAAGAACGACCCAGCCTTCCAGAACCCGAGCAAGCCGGTCG
GCCCGTTCTACGACGAGGAGACTGCCAAGAAGCTAGCAAAGGAAAAGGGCTGGACGGTTATAGAAGACGCCGGGAGGGGC
TGGAGGAGGGTAGTTCCGAGTCCCGACCCGAAGGGGCACGTAGAGGCTCCGGTCATAGTTGACCTCGTCGAGAAGGGCTT
CATCGTCATAGCGAGCGGCGGCGGTGGCGTCCCAGTGATTGAGGAGAATGGAGAGCTTAAGGGCGTTGAGGCGGTTATAG
ACAAAGATTTAGCCGGTGAAAAGCTGGCTGAAGAGGTTAAAGCGGATATCTTCATGATACTCACGGACGTGAACGGCGCG
GCAATAAACTACGGAAAGCCCGATGAGAAGTGGCTCGGGAAGGTAACCGTGGACGAGCTGAAGCGCTATTACAAAGAGGG
CCACTTCAAGAAGGGAAGCATGGGGCCGAAGGTTCTTGCCGCGATAAGGTTCGTTGAGTGGGGAGGCGAGAGGGCAGTAA
TAGCTTCCCTTGACAGGGCCGTCGAGGCGCTTGAGGGGAAGACGGGGACGCAGGTTGTACGGGAGTGA

Protein sequence :
MKRVVIALGGNAILQRGQKGTYEEQMENVRRTAKQIADIILDGDYEVVITHGNGPQVGALLLHMDAGQQVYGIPAQPMDV
AGAMTQGQIGYMIGQALINELRKRGVEKPVATIVTQTIVDKNDPAFQNPSKPVGPFYDEETAKKLAKEKGWTVIEDAGRG
WRRVVPSPDPKGHVEAPVIVDLVEKGFIVIASGGGGVPVIEENGELKGVEAVIDKDLAGEKLAEEVKADIFMILTDVNGA
AINYGKPDEKWLGKVTVDELKRYYKEGHFKKGSMGPKVLAAIRFVEWGGERAVIASLDRAVEALEGKTGTQVVRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arcC1 YP_186045.1 carbamate kinase Not tested vSa¥ã Protein 7e-59 47
MW1051 NP_645868.1 carbamate kinase Not tested vSa¥ã Protein 7e-59 47
SAV1170 NP_371694.1 carbamate kinase Not tested vSa¥ã Protein 7e-59 47
SA1013 NP_374286.1 carbamate kinase Not tested vSa¥ã Protein 7e-59 47
arcC YP_493761.1 carbamate kinase Not tested vSa¥ã Protein 7e-59 47
SE0102 NP_763657.1 carbamate kinase Not tested SCCpbp4 Protein 4e-57 47
SAKOR_01091 YP_008491279.1 Carbamate kinase Not tested vSa¥ã Protein 6e-59 47
APECO1_2636 YP_859422.2 carbamate kinase Not tested Not named Protein 5e-59 47