Gene Information

Name : nrdE (ABC3108)
Accession : YP_176603.1
Strain : Bacillus clausii KSM-K16
Genome accession: NC_006582
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 3234374 - 3236470 bp
Length : 2097 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGGCACAAGTTCCAAAGTGGGTTCAGCTTAACAACGAGCTAATGATTACAAAGGACGGCGGCTACCAGTTTGAAAAGGA
CAAAGAAGCTGTACATAGCTATTTCGTAGACTACATTAACCAAAACACCGTCTTTTTCCATGATCTTGAAGAAAAGATCG
ACTACTTAATTGAAAATGATTATTACGAAGAAGAGCTTCTGCGCTTGTATACGATCGACGAAATTAAAGCAGTGATGGAC
ATTGCCTATAACAAAAAATTCCGTTTCCCGTCGTTCATGAGCGCTTTTAAATTTTACAATGATTACGCGCTAAAAACGAA
TGACAAAAGCAAAATTTTAGAGCGATATGAAGACCGTGTCGCCATTGTTTCCCTTTTCTTCGGAAACGGGGATGTTGAAA
AAGCCAAAGCGTTAGTAAATGCCATGATTTCGCAAGAGTTCCAGCCAGCGACGCCCACGTTCCTCAATGCAGGACGTAAA
CGGCGCGGCGAACTCGTTTCCTGCTTCTTGCTTGAAATTAACGATTCATTAAATGACATTAGCCGAGCTGTCGACATTTC
AATGCAGCTCTCAAAGCTTGGCGGCGGTGTGGCCCTTAACTTATCAAAGCTACGCGCGAAAGGCGAGGCAATCAAAGACG
TGGCTAACGCAACAAAAGGCGTTGTCGGCGTCATGAAACTTCTCGACAATGCGTTTCGCTATGCCGACCAAATGGGGCAG
CGCCAAGGGTCTGGTGCAGCGTACTTAAATATTTTCCACGCTGACATTAACGACTTTCTTGACACGCGGAAAATTTCTGC
TGATGAAGACGTACGCGTTAAAACATTGTCGATTGGCGTCGTTATCCCTGACAAGTTTATTGAGTTGATGCGCGAAGATA
AAGATGCATACTTGTTTTATCCACATACTGTTTATAAAGCTTACGGCCAACATTTTGATGAAATGGACATGGAAGAAATG
TACGAAACGCTTGTTGACGACCCGCGGGTACGGAAAGAAAAAATCAACCCTCGTCGTCTGTTCCAAAAGCTGGCGATCTT
GCGGTCCGAATCCGGCTACCCATACATTATGTTTGCCGATAACGTGAACAAGGCCCATGCAAATGGCCATATTAGTAATG
TCAAGTTTTCAAACTTATGTTCGGAAATCTTACAAGCCTCAGAAGTATCGACTTACACCGACTACGGCGAGGAAGATGAA
ATCGGCCTTGACATTTCCTGCAACCTTGGGTCGATTAACATTATGAATGTGATGGAAAACAAATCGCTTGAAAACACGGT
TAGCCTGGCGACAGACGCTTTAACGCGCGTATCAGAGTCAACCAATATTACAAATGCGCCAGCTGTGCGCCGCGGTAACA
AACTGATGAAATCAATCGGCCTAGGCGCAATGAATTTGCACGGTTACCTAGCGAAGCAGCATATTGCTTACGAAAGCGAA
GAAGCTCGTGATTTTGCCAATACCTTTTTTATGGCGATGAACTATTTCTCTATTAAACGGTCTGCTGAGATTGCCAGGGA
CCAAGGTGAAACGTATCACGGTTATGAAGGCAGCACGTACGCTGACGGCTCCTACTTTAAAAAGTATATCGAAAATGACT
TCACGCCTAAATTTGACAAAGTCAAAGCGCTGTTTGACGGCATGTTTGTGCCAACAAAAGAAGATTGGCAAGCTTTGCAA
GCCTTTGTTGCAGAACACGGCCTTTACCATAGTTACCGATTGGCGATCGCGCCAACTGGTTCGATTTCTTATGTACAGTC
GGCCACGGCAAGCGTCATGCCGATCATGGAACGGATTGAAGAACGGACATACGGCAACTCCAAAACATACTATCCAATGC
CTGGGCTTAATGCGAACAATTGGTTCTTCTACAAAGAAGCCTATGACATGGATATGTTTAAAGTCGTTGATATGATTGCA
ACGATCCAACAACACGTCGATCAAGGGATCAGCTTTACGCTTTTCCTAAAGGATACGATGACGACCCGTGATTTGAACCG
AATCGACCTTTATGCGCACCATAAAGGCATCAAAACCCTTTACTACGCGCGCACAAAAGATACAGGGCAAGACAACTGCC
TTTCTTGTGTCGTTTAA

Protein sequence :
MAQVPKWVQLNNELMITKDGGYQFEKDKEAVHSYFVDYINQNTVFFHDLEEKIDYLIENDYYEEELLRLYTIDEIKAVMD
IAYNKKFRFPSFMSAFKFYNDYALKTNDKSKILERYEDRVAIVSLFFGNGDVEKAKALVNAMISQEFQPATPTFLNAGRK
RRGELVSCFLLEINDSLNDISRAVDISMQLSKLGGGVALNLSKLRAKGEAIKDVANATKGVVGVMKLLDNAFRYADQMGQ
RQGSGAAYLNIFHADINDFLDTRKISADEDVRVKTLSIGVVIPDKFIELMREDKDAYLFYPHTVYKAYGQHFDEMDMEEM
YETLVDDPRVRKEKINPRRLFQKLAILRSESGYPYIMFADNVNKAHANGHISNVKFSNLCSEILQASEVSTYTDYGEEDE
IGLDISCNLGSINIMNVMENKSLENTVSLATDALTRVSESTNITNAPAVRRGNKLMKSIGLGAMNLHGYLAKQHIAYESE
EARDFANTFFMAMNYFSIKRSAEIARDQGETYHGYEGSTYADGSYFKKYIENDFTPKFDKVKALFDGMFVPTKEDWQALQ
AFVAEHGLYHSYRLAIAPTGSISYVQSATASVMPIMERIEERTYGNSKTYYPMPGLNANNWFFYKEAYDMDMFKVVDMIA
TIQQHVDQGISFTLFLKDTMTTRDLNRIDLYAHHKGIKTLYYARTKDTGQDNCLSCVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 4e-169 49