Gene Information

Name : smpB (ABC3002)
Accession : YP_176497.1
Strain : Bacillus clausii KSM-K16
Genome accession: NC_006582
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 3123392 - 3123877 bp
Length : 486 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGCAGGTGGAATGCATGGGAGAAACGACAGAAGGCAAAGTTGTTGCGCAAAATAAAAAAGCACGCCATGATTATTTTAT
CGAAGAAACATTTGAAGCGGGCATTGTCCTAACCGGAACAGAAATCAAGTCGATTCGGGCGGGGAAAATGAATTTAAAAG
ATTCCTTTGCCCGCATCAAAAATGGCGAAGCTTTTTTGTACAATGCCCACATTAGTGAATACGAACAAGGCAACCGCTAC
AACCATGAACCGACACGGCCGCGCAAACTGTTGCTCCATAAAAAACAAATCAATACATTAATTGGGCAAACGCAGCAAAA
AGGCTATTCAATCGTTCCATTAAAAGTCTATATTAAAAACGGCTTTGCCAAAGTGCTTATCGGCCTTGCAAAAGGGAAGA
AAAACTACGATAAGCGGGAAACATTACGGCGAAAAGACGCGAAGCGCGAAGTGGAACGGGCAATAAAAGAGCGCATGCGC
GGTTAA

Protein sequence :
MQVECMGETTEGKVVAQNKKARHDYFIEETFEAGIVLTGTEIKSIRAGKMNLKDSFARIKNGEAFLYNAHISEYEQGNRY
NHEPTRPRKLLLHKKQINTLIGQTQQKGYSIVPLKVYIKNGFAKVLIGLAKGKKNYDKRETLRRKDAKREVERAIKERMR
G

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-42 64
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 7e-32 46
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 7e-27 43