Gene Information

Name : leuS (ABC2871)
Accession : YP_176366.1
Strain : Bacillus clausii KSM-K16
Genome accession: NC_006582
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2998645 - 3001059 bp
Length : 2415 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCGTTTTCACATCAGGAGATTGAAAAAAAATGGCAAGCATTTTGGGAAGAAAACAAAACGTTTAAAACAGACGAACA
AGCAGAAGGGCCACATTTTTATGCATTAGATATGTTTCCCTACCCATCAGGGGCTGGTCTTCATGTCGGCCATCCAGAGG
GATACACGGCAACGGATATTTTAGCGCGGATGAAGCGGATGCAAGGCTACAATGTTCTTCATCCTATGGGTTGGGATGCT
TTTGGCTTACCAGCTGAGCAGTACGCTTTAGATACAGGCAAACACCCGGCTACATTTACTAAACAAAACATTGACACCTT
TAAACGGCAAATTAAAGAACTTGGTTTTTCTTACGATTGGGATCGTGAAATTAGTACGACTGATCCTCACTATTACAAAT
GGACACAATGGATTTTTCTGAAATTATATGAAAAAGGGCTTGCTTATATTGACGAAGTAGCCGTGAACTGGTGCCCGGCA
CTGGGGACTGTGCTAGCCAATGAGGAAATTGTCGACGGTGTCAGCGAACGAGGAGGCCATCCAGTTGAAAGGCGCCCAAT
GAAACAATGGGTGTTGCGCATTACGGCTTATGCTGAGCGCTTGCTCGAAGACCTTGAAGAGCTGGAATGGCCGGAAAGCC
TAAAAGATATGCAGCGCAACTGGATCGGCAAATCGGAAGGCGCTGAAGTGACATTTAAGATCAATGAACATTCCGTTAAC
GTGTTTACGACGCGGCCAGACACGTTGTTTGGCGCTACTTATATGGTGCTTGCCCCTGAGCATAAGCTCGTGACTGAGAT
CACTACCGATGAGCAAAAGGAAGCGGTAGAAGCATACCAAAAGCAAGTCGCGCTCAAAAGTGACATTGAACGGACAGATT
TGGCAAAAGAAAAAACAGGCGCGTTTACTGGCGCTTATGCCATCAATCCTGTAAATGGCGAAAAGATTCCAGTTTGGATA
GCTGATTATGTACTAATCAGTTATGGCACTGGAGCTGTCATGGCTGTTCCTGCCCATGATGAGCGTGATTTCGAATTTGC
TAATGCATTTGGCTTGCCAATAAAAGAAGTGGTCGCAGGCGGAGATGTCTCAAAAGCTGCTTACACAGGGGACGGAGAAC
ATGTTAATTCTGATTTTCTCAATGGGTTAAACAAGCAAGAAGCGGTTGAGAAAATGATTGTCTGGCTAGAGGAAAATGGC
GCTGGGCAAAGAAAGGTCACATACCGCCTGCGTGATTGGCTCTTTAGCCGCCAGCGTTATTGGGGCGAACCGATTCCAAT
TATCCACTGGGAAGATGGCTCTATGTCAGCTCTGGATGAGAGCGAATTGCCGCTTGTGTTGCCTGATCTAGAGGAAATCA
AACCTTCGGGTACAGGCGAATCGCCGCTTGCTAATGCGAAAGATTGGCTGGAAGTTGTTGATCCTAAAACAGGCATGCGC
GGTCGCCGTGAAACGAACACGATGCCCCAATGGGCAGGTAGCTGCTGGTATTATTTGCGCTATATCGACCCGACAAACGA
CGAAGCGTTGGCTGATCCTGAAAAACTAAAGAATTGGCTGCCTGTCGATACGTATATTGGCGGTGCGGAACATGCAGTGT
TGCATTTGCTATATGCACGTTTTTGGCATAAGTTTTTGTATGATATTGGCGTTGTGCCGACAAAAGAACCATTCCAAAAA
GTGTTTAACCAAGGCATGATCCTTGGCGAAAATAACGAAAAGATGAGCAAGTCAAAAGGCAATGTTGTGAACCCTGATGA
GATTATTGCCAGCCACGGGGCTGACACGCTGCGCCTGTATGAAATGTTTATGGGCCCTCTAGATGCATCTGTAGCTTGGT
CAACAAACGGCCTTGATGGCTCGCGCCGTTTTCTTGAACGGGTTTGGCGCCTGATTGTTAACGAAGAAACAGGCAAGCTG
AACAGCAACGTCAAAGATGTAGAAGGCAATGAAGCGTTTGTGCGCACTTACCACCAAACAGTGAAAAAAGTAACCGAAGA
CTTTGCCGAGCTGCGCTTTAATACAGGGATTTCCCAATTAATGGTGTTTGTAAACGAGGGAAATAAGCAAGAGGTATTGC
CAAAAGCGCTAATAGAGGGCTTTGTGAAGCTTTTGTCGCCAGTTGCTCCTCATATTGCCGAAGAGCTGTGGGAAAAGCTT
GGCCATACAGATACGATTACGTATGAAGCGTGGCCGACATATGATGAGTCGTTGCTCGTTGAAAACGAAGTTGAGGTCGT
CGTGCAAATGAACGGCAAAGTTAAAACAAAGCTCGTTATAAACAAAGGAGCCTCAAAAGAAGAAATGGAAGCAGCAGCAC
TCGCTGATGAAAAAGTGCAAGCAGCTATCGGCGAGAAAACGATTCGCAAAGTCATCGCTGTTCCTGGAAAGCTTGTCAAT
ATTGTTGTTGGTTAA

Protein sequence :
MSFSHQEIEKKWQAFWEENKTFKTDEQAEGPHFYALDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGKHPATFTKQNIDTFKRQIKELGFSYDWDREISTTDPHYYKWTQWIFLKLYEKGLAYIDEVAVNWCPA
LGTVLANEEIVDGVSERGGHPVERRPMKQWVLRITAYAERLLEDLEELEWPESLKDMQRNWIGKSEGAEVTFKINEHSVN
VFTTRPDTLFGATYMVLAPEHKLVTEITTDEQKEAVEAYQKQVALKSDIERTDLAKEKTGAFTGAYAINPVNGEKIPVWI
ADYVLISYGTGAVMAVPAHDERDFEFANAFGLPIKEVVAGGDVSKAAYTGDGEHVNSDFLNGLNKQEAVEKMIVWLEENG
AGQRKVTYRLRDWLFSRQRYWGEPIPIIHWEDGSMSALDESELPLVLPDLEEIKPSGTGESPLANAKDWLEVVDPKTGMR
GRRETNTMPQWAGSCWYYLRYIDPTNDEALADPEKLKNWLPVDTYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQK
VFNQGMILGENNEKMSKSKGNVVNPDEIIASHGADTLRLYEMFMGPLDASVAWSTNGLDGSRRFLERVWRLIVNEETGKL
NSNVKDVEGNEAFVRTYHQTVKKVTEDFAELRFNTGISQLMVFVNEGNKQEVLPKALIEGFVKLLSPVAPHIAEELWEKL
GHTDTITYEAWPTYDESLLVENEVEVVVQMNGKVKTKLVINKGASKEEMEAAALADEKVQAAIGEKTIRKVIAVPGKLVN
IVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 66