Gene Information

Name : polA (ABC2709)
Accession : YP_176205.1
Strain : Bacillus clausii KSM-K16
Genome accession: NC_006582
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2840762 - 2843395 bp
Length : 2634 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
TTGAAAAAATTAGTGCTTATTGACGGCAACAGCATTGCTTACCGTGCATTTTTTGCATTGCCGCTTTTAAATAATGAAAA
AGGCGAATATACAAATGCTGTCTACGGCTTTACGACCATGTTGTTGAAGGTTCTCGAAGACGAAAAACCGAGCCATATGC
TTGTCGCCTTTGATGCAGGGAAATCGACGTTCCGCCATCAGACTTATGCGGCTTATAAAGGCACGAGGCAGAAAACGCCA
TCAGAGCTATCTGGGCAAATTCCAATGATTCACCAAGTGCTCGATGCGTTTTCGATTAAGCGTTATGAAGTAGACGAATA
CGAAGCAGACGACATTATCGGCACGGCGGCAACGAATGCAGCAAAAGAAGGCTTTGACGTTGTTGTCATTACAGGTGATA
AAGATTTGCTTCAATTGGTTGATGACCGTGTTGAAGTCGTGCTGACGAAAAAAGGCATTTCTGAAGTGGATCGCTATAAT
CGTGAAAAAGTGGCTGAACGCTACGGGCTTGAACCGAAACAAATTATTGATTTAAAAGGGTTAATGGGCGATTCGTCTGA
TAACATTCCAGGTGTTCCCGGCGTAGGTGAGAAAACGGCACTAAAATTGCTTGCCGAATTCCGCGACGTAGAAACGGTGC
TTGATTCGATTGATGCGATCTCTGGGAAGAAGCTGAAAGAACGTCTTCAAGAGAATAAAGACCAAGCCCTCCTAAGCAAA
AAACTCGCCACAATTGCCCTTGACGTGCCACTTGCCGAAACGCTTGATTCGTTCGAGTATGGCGGATATGAGTATAAACA
AGTTAAAGAAGCGTTTAAAGAGCTGTCTTTTCATTCGTTGCTTGGCCGCATTGACGGCAACGGCGATGAAGAAAGTGCAC
CACAGCAATTGACGGAACTGGATTTTGATATCGTTGAAGAACCGTTGCCTGAACATTTTTCCAGCCCGTCAGCTTTAGTC
GTCGAAGTGTTAGCGGAAAACTACCATCAAGCCGAAATTGCCGGTATGGCGGTGGCGAACGAGAAGGGCTGCTTTTATTT
CCCGACTGAGAAAGCAGTGAAGTCAGACGCGTTTAGGGCATTTGCCCGTTCGCAAGAAAAAAAGAAATGGCTGTTTGACG
CAAAGCGCGCTGTCGTCGCTTTAGCCTGGCATGGGGTTGACTTAAACGGCGTTGATTTTGACTTGCAAATGGCTTCCTAT
TTGCTCGATCCATCGCTGTCATCCCACGAAATTAGCGACATTGCTACCCGTAAAGGGACAGGTGGCGTGGCTGAAGATGA
AGCTGTATACGGCAAAGGCGCCAAGCGCTCTCTTCCAGAAGAGGCCGCCCTAGCCGAACATCTTTGCCGTAAAGCGAATG
CCATGTTTACGTTAAAAAGCACATTGGAAGATGAACTGGCGCAAAATGAGCAGCTTGAATTGCTCAAGAAGTTAGAAATG
CCATTGTCTGTTGTACTTGGCCGTATGGAAAAAGAAGGTGTCCGTGTCGACCGAGAACAACTTGAGGAAATGGGCAAAGA
TTTATCGGATCGCTTGAACACTCTAGAAAAGGCGATTCATAAAGAAGCTGGAGAACCATTCAATATTAATTCACCGAAAC
AGCTTGGCGTTATCCTGTTTGAAAAACTAGGGTTGCCGCCTGTGAAAAAAACAAAAACAGGCTATTCCACTAGTGCTGAT
GTATTGGAAAAACTTGCAGGCACACATCCAATTATTGAACACCTTCTTCTTTACCGGCAACTTGGCAAGCTCTATTCAAC
ATACATCGAAGGGTTGCTTAAAGTGATCGATTCGGAAACAGGGAAAGTCCATACCCGTTTTAACCAAGCTTTAACGCAAA
CAGGACGCCTTTCGTCGACAGACCCGAATTTGCAAAACATCCCTATCCGTTTAGAGGAAGGGAGAAAAATCCGCAAAGCA
TTCGTTGCCTCGAAGGAAGGCTGGAAAATAGTTGCGGCTGATTACTCGCAAATTGAGCTCCGTGTCCTCGCCCATATTTC
TGGCGATGAACGGATGAAGGAAGCGTTTTTAACGGGGATGGACATCCATACAAAAACGGCAATGGATGTTTTCCATGTAA
AACGTGAGGAAGTTACTGATTTGATGAGAAGGAGCGCGAAGGCCGTCAATTTTGGGATTGTCTACGGCATAAGCGATTAT
GGGCTCTCACAAAGCCTAGGAATTACGAGAAAAGAAGCGAAAGACTTTATCGACCGCTATTTAGCAAGTTATCCACAAGT
GAAAGCTTATATGGAGAATGTGGTGAAAGAAGCAAAGGAGAAGGGGTATGTCCAAACACTGCTTGCGAGAAGGCGTTATT
TGCCTGAACTGAAAAGCCGCAATTTCAATCAGCGCAGTTTTGCAGAACGGACAGCGATGAACACACCCATCCAAGGGACC
GCAGCTGACATTATTAAACGGGCGATGGTGAAAATGAGTGAAGCGTTAGAAGAAACAGGGCTTAAAGCAAACATGTTGCT
CCAAGTCCATGACGAACTCATTTTTGAAGTGGCGCCTGACGATGTGGAACCGTTACAAGAGCTTGTCACAGAAGTAATGG
AACAGGCACTTGAGCTTGATGTGCCTTTACAAGTGGATGTCTCTAGCGGAAATTCATGGTTTGACGCGAAATAA

Protein sequence :
MKKLVLIDGNSIAYRAFFALPLLNNEKGEYTNAVYGFTTMLLKVLEDEKPSHMLVAFDAGKSTFRHQTYAAYKGTRQKTP
SELSGQIPMIHQVLDAFSIKRYEVDEYEADDIIGTAATNAAKEGFDVVVITGDKDLLQLVDDRVEVVLTKKGISEVDRYN
REKVAERYGLEPKQIIDLKGLMGDSSDNIPGVPGVGEKTALKLLAEFRDVETVLDSIDAISGKKLKERLQENKDQALLSK
KLATIALDVPLAETLDSFEYGGYEYKQVKEAFKELSFHSLLGRIDGNGDEESAPQQLTELDFDIVEEPLPEHFSSPSALV
VEVLAENYHQAEIAGMAVANEKGCFYFPTEKAVKSDAFRAFARSQEKKKWLFDAKRAVVALAWHGVDLNGVDFDLQMASY
LLDPSLSSHEISDIATRKGTGGVAEDEAVYGKGAKRSLPEEAALAEHLCRKANAMFTLKSTLEDELAQNEQLELLKKLEM
PLSVVLGRMEKEGVRVDREQLEEMGKDLSDRLNTLEKAIHKEAGEPFNINSPKQLGVILFEKLGLPPVKKTKTGYSTSAD
VLEKLAGTHPIIEHLLLYRQLGKLYSTYIEGLLKVIDSETGKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRKA
FVASKEGWKIVAADYSQIELRVLAHISGDERMKEAFLTGMDIHTKTAMDVFHVKREEVTDLMRRSAKAVNFGIVYGISDY
GLSQSLGITRKEAKDFIDRYLASYPQVKAYMENVVKEAKEKGYVQTLLARRRYLPELKSRNFNQRSFAERTAMNTPIQGT
AADIIKRAMVKMSEALEETGLKANMLLQVHDELIFEVAPDDVEPLQELVTEVMEQALELDVPLQVDVSSGNSWFDAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 49