Gene Information

Name : hemC (ABC2630)
Accession : YP_176126.1
Strain : Bacillus clausii KSM-K16
Genome accession: NC_006582
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2754178 - 2755113 bp
Length : 936 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGAAAGATTGTGATTGGCACACGCCGAAGCAAATTGGCGTTAACGCAAACGAATTGGGTCATTGACCAGCTTAAACA
GCTTGGCGTTCCCTATGAGTTTGAAGTGAAAGAAATTGTGACGAAGGGCGACCGCATTCTCGATGTGACGTTATCAAAAG
TAGGCGGGAAAGGGTTGTTTGTTAAAGAAATTGAAGCAGCGCTCCGCTCTGGGGAAATTGACGTTGCAGTCCACTCAATG
AAAGACGTGCCTTCCGAACTGTTGGAAGAATTCACCCTTGCTGCAATTACAGAGCGAGAAGATCCACGGGATGTGCTTGT
GAGCGAAAATGGCCACACACTGGACGAGCTCCCAGCTGGTGCAATTGTCGGAACGAGCAGCTTACGGCGTTCTGCGCAAA
TTTTACATAGGCGCCCAGACGTGCAAGTGAAATGGATACGGGGCAATGTGGAGACCCGTTTGCGCAAACTAAAAGAGGAA
GATTTTTCGGCGATTGTCTTGGCTGCAGCTGGGTTAAAGCGGCTTGGCTATGGCGAGGACGTCATCACCGAATACTTAGA
CAAAGACGTATGCTTGCCTGCGATTGGCCAAGGGGCGCTAGGGCTTGAATGCCGTGTGGATGACGTAGAAACAACGGAAC
TGTTAGCAAAGCTGCACCATGAAGAAACAGGAAAAGCCGTTTTGGCAGAACGAGCCTTTTTAAAGGAAATGAACGGTGGT
TGCCAAGTGCCGATTGGCGGGTATGCAACGGTGCTTGAGGATGGCGCAGTATTCCTGACAGGGCTTGTCGGTTCTCCTGA
CGGCAAAACGATACTAAAAGAAGGAAAATGCGGAATGGTTGCGGATGAGCTAGGGAAAGAGGTGTCTAGCCTGTTGACTG
CACAAGGGGCTGGAGCGATTCTTGAAAAGGTCAGGAGCGAACTGGAAGGGTCATGA

Protein sequence :
MRKIVIGTRRSKLALTQTNWVIDQLKQLGVPYEFEVKEIVTKGDRILDVTLSKVGGKGLFVKEIEAALRSGEIDVAVHSM
KDVPSELLEEFTLAAITEREDPRDVLVSENGHTLDELPAGAIVGTSSLRRSAQILHRRPDVQVKWIRGNVETRLRKLKEE
DFSAIVLAAAGLKRLGYGEDVITEYLDKDVCLPAIGQGALGLECRVDDVETTELLAKLHHEETGKAVLAERAFLKEMNGG
CQVPIGGYATVLEDGAVFLTGLVGSPDGKTILKEGKCGMVADELGKEVSSLLTAQGAGAILEKVRSELEGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-60 53
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-60 53