Gene Information

Name : metI (ABC1867)
Accession : YP_175363.1
Strain : Bacillus clausii KSM-K16
Genome accession: NC_006582
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1983395 - 1984501 bp
Length : 1107 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGGAAAAACGAGCTGAAACCATCTTAGCGCAAATTGGCAATCGCCGCGATGAACATACTGGCGCAGTAAACACGCCTGT
TTATTTTTCAACAGCATATCGCCATCCAGGTATTGGCGAATCGACTGGGTATGATTATGCCCGTACAGGCAATCCGACAA
GGGACGTGCTCGAAAAAGCGATTGCGGAATTAGAAGAAGGTGAGCGCGGATTTGCGACTAGCTCTGGCATGGCTGCTGTT
CAAATTGTGCTTTCGTTGTTTGAGCAAGGCGATGGGATCATCTGTTCGAAAGATTTATATGGCGGTACGTACCGTCTGTT
TGAAGGAGGCTGGACAAGGTGGGGCGTGTCCTTTACATATGTGGATCCACGGAATTTGCAAGAAGTCGAACAAGCCATTC
ATTCTAACGTGAAAGCCATTTTTATCGAGACGCCGACTAACCCACTTATGCAGGAAGCCTCGATTCCAGCGCTTGCTGCT
CTCGCCAAAAAACACGATTTGCTGCTCATTGTCGATAACACATTTTATACGCCGCTTTTGCAGAAGCCACTAACGGAAGG
AGCAGACATCGTGATCCATTCGGCGACAAAGTACTTAGGAGGCCATAACGATGTCGTTGCTGGGCTTATCGTTGCGAAAG
GAGCCGATCTTTGTGAACGGCTCGCTTATTATCATAATGGTGCTGGTGGTATTTTAAGTGCATTTGATTCTTGGCTGCTT
ATTCGAGGAATGAAGACATTGGCATTGCGGATGGCCAAGCATGAGGAAAACGCTAAAAAAGTGGTGCATGCATTGGAGCA
AACAGACGGCATTGTAGACGTGCTTTATCCTGGGAGAGGCGGAATGCTGTCGTTTCGTGTTCAAAACGAAGCTTGGGTCA
ATCCGTTGCTAAAACATTTGCAATTAATTTCGTTCGCGGAAAGCCTCGGTGGTGTCGAAAGTTTAATGACATATCCAGCA
ACACAAACGCACGCTGATATTCCCGAAGAGATCAGACTTGCAAATGGAGTGGATAATGGATTGCTCCGTTTCTCAGTCGG
CATTGAAAACGGAGAAGATATTGTAGCTGATTTGCTGCAAGCAATTGCGGCCGCTAAAAAATCCTAG

Protein sequence :
MEKRAETILAQIGNRRDEHTGAVNTPVYFSTAYRHPGIGESTGYDYARTGNPTRDVLEKAIAELEEGERGFATSSGMAAV
QIVLSLFEQGDGIICSKDLYGGTYRLFEGGWTRWGVSFTYVDPRNLQEVEQAIHSNVKAIFIETPTNPLMQEASIPALAA
LAKKHDLLLIVDNTFYTPLLQKPLTEGADIVIHSATKYLGGHNDVVAGLIVAKGADLCERLAYYHNGAGGILSAFDSWLL
IRGMKTLALRMAKHEENAKKVVHALEQTDGIVDVLYPGRGGMLSFRVQNEAWVNPLLKHLQLISFAESLGGVESLMTYPA
TQTHADIPEEIRLANGVDNGLLRFSVGIENGEDIVADLLQAIAAAKKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-70 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-71 45