Gene Information

Name : guaA (syc1322_d)
Accession : YP_172032.1
Strain : Synechococcus elongatus PCC6301
Genome accession: NC_006576
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1431748 - 1433352 bp
Length : 1605 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACGCTCCAGACTGAAATGGAGGCTGCACTTGAAGTTGCAGCCTTGAACCGTGAAATGTTGATCATTCTGGACTTCGG
GTCGCAGTACTCGGAGCTGATTGCTCGCCGCATTCGCGAAACGCAAGTTTATTCAGAAGTGCTGTCCTACCGCACCACGG
CGGATCAAATTCGGCAGCTGTCTCCCAAGGGCATCATCCTTTCAGGCGGCCCTAATTCGGTCTACGACGACTACGCGCCA
GTTTGCGATCCAGAAATCTGGAATCTGGGAATTCCGGTGCTGGGCGTCTGCTACGGCATGCAGCTGATGGTGCAACAGCT
AGGGGGCCAAGTCGATCGCGCCGAGCGTGGCGAATATGGCAAGGCAGCGTTGGTCATCGACGATCCGACCGATTTGCTGA
CCAACGTCGAACCGGGCTCGACCATGTGGATGAGCCATGGCGACTCTGTCAAAACCATGCCCGAGGGCTTTGAGCTGCTC
GCCCACACCGATAACACCCCCTGCGCTGCGATCGCGGATCACCAGCGCAAGTTCTACGGCGTGCAGTTCCACCCGGAAGT
CGTGCATTCCGTGCATGGCATGGCGCTGATTCGCAACTTTGTCTATCACATTTGCGATTGCGAACCGACTTGGACAACGG
AAACCTTTGTCGAAGAAGCGATTCGCGAAATTCGGGCACGAGTCGGTGATAAGCGCGTTCTCCTAGCGCTATCCGGCGGT
GTAGATTCTTCGACGCTGGCCTTCCTGTTACATCGGGCAATCGGCGATCAGCTGACCTGTATGTTCATTGATCAGGGCTT
CATGCGCAAAGGCGAACCGGAGCGCTTGATGGAGGTATTCAACGAGAAATTCAAGATTCATGTTGAATATATTCAAGCTC
GCGATCGCTTCTTACAGCGACTGGAAGGCATCACCGATCCCGAAGAAAAACGCAAACGGATTGGCCACGAATTCATTCGC
GTTTTTGAAGAAGAATCGCGTCGGCTCGGCCCCTTCGACTATCTGGCCCAAGGCACGCTCTATCCCGATGTGATTGAGTC
GGCAGACACTAACGTCGATCCCAAAACGGGCGAGCGAGTGGCGGTCAAGATCAAGAGCCACCACAACGTCGGTGGTCTGC
CCAAAGACCTCCAGTTCAAGCTAGTTGAACCGCTGCGGCGTCTGTTCAAAGATGAAGTGCGTCAGGTTGGGCGATCGCTG
GGTCTACCAGAAGAAATCGTCAAGCGCCATCCGTTCCCAGGCCCGGGCCTCGCGATTCGGATTCTGGGTGAAGTCACAGC
TGAAAAGCTCAACATCCTGCGCGATGCAGACTTGATTGTTCGCCAGGAAGTCAACCGTCAGGGCTATTACGACGAGTTCT
GGCAAGCCTTCGCTGTGCTGCTGCCGGTCAAGAGTGTCGGTGTGATGGGCGACAAGCGCACCTACGCCTACCCTGTTGTG
CTGCGTTTTGTCAGCAGTGAAGACGGCATGACCGCTGACTGGTCGCGGGCTCCCTACGACCTACTGGAGACGATTTCGAA
TCGGATTGTCAACGAAGTGAAAGGCGTCAACCGCGTCGTCTACGACATCACCTCGAAACCCCCTGGCACGATCGAGTGGG
AATGA

Protein sequence :
MTLQTEMEAALEVAALNREMLIILDFGSQYSELIARRIRETQVYSEVLSYRTTADQIRQLSPKGIILSGGPNSVYDDYAP
VCDPEIWNLGIPVLGVCYGMQLMVQQLGGQVDRAERGEYGKAALVIDDPTDLLTNVEPGSTMWMSHGDSVKTMPEGFELL
AHTDNTPCAAIADHQRKFYGVQFHPEVVHSVHGMALIRNFVYHICDCEPTWTTETFVEEAIREIRARVGDKRVLLALSGG
VDSSTLAFLLHRAIGDQLTCMFIDQGFMRKGEPERLMEVFNEKFKIHVEYIQARDRFLQRLEGITDPEEKRKRIGHEFIR
VFEEESRRLGPFDYLAQGTLYPDVIESADTNVDPKTGERVAVKIKSHHNVGGLPKDLQFKLVEPLRRLFKDEVRQVGRSL
GLPEEIVKRHPFPGPGLAIRILGEVTAEKLNILRDADLIVRQEVNRQGYYDEFWQAFAVLLPVKSVGVMGDKRTYAYPVV
LRFVSSEDGMTADWSRAPYDLLETISNRIVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-139 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-128 52