Gene Information

Name : clpB (FTT_1769c)
Accession : YP_170660.1
Strain : Francisella tularensis SCHU S4
Genome accession: NC_006570
Putative virulence/resistance : Virulence
Product : ClpB protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1857728 - 1860307 bp
Length : 2580 bp
Strand : -
Note : Similar to FASTA: AAO89660 (Q83F55) ClpB protein from Coxiella burnetii (859 aa). FASTA: opt: 3593 Z-score: 3223.6 E(): 1.1e-171 Smith-Waterman score: 3593; 65.357 identity in 840 aa overlap

DNA sequence :
ATGGATATAAATAAATTTACAATAAAACTACAAGAAGCTCTAGCTGAGGCTCAATCTTATGCTTTTCAACAAAAAGCAAC
TGAGTTTACATCAGCACATATACTAAAAGCTCTTTTGGAGCAAAATGATAGTGTTGCTATATCTATATTAAGCGTTTGTG
GTGTTAATATACAAAACTTTATAAAAGCTGTAAATGATATGGTTGATAGTGTTGCGGTATTATCTGGAGAAGGTAACCCT
CAAGTAACACCATCTAGAGATTTAATAGCTACATTACATAAAATGCAAGGGCTTGCTAATAAAAATGGTGATGAGTTTAT
CTCGAGTGAGGTTTTCTTATTAGCCTCTTTAGAAGACAAAAGTTTAACTGGACTGTATAACAAATTTGGTATTACAAAAG
AAAAATTAACAAAAGCAGTCAATGATTATCGCGGAGGGGAGAAAGTGAGTAGTCAAAATCAAGAAGATATGAAAGGTGCA
TTAGATAAATACACGGTAGATCTAACTGATCTAGCGAGAAAAGGAAAAATTGATCCAATAATCGGTAGAGATAGTGAGAT
CCGTAGAACTATTCAAGTATTACAAAGAAGAACTAAGAACAACCCTGTGCTTATAGGTGAGCCTGGTGTTGGTAAAACTG
CTATTGTTGAGGGCTTAGCTCAACGAATAGTTAATGATGAAGTACCAGAAGGTGTCAAAGGTAAAAAAGTACTATCATTA
GATATGGGTGCACTGCTAGCTGGTGCTAAATTTAGAGGAGATTTTGAAGAGCGTCTAAAATCTGTATTAAAAGAGTTATC
AAAACAAGAAGGTAATGTAATTCTCTTTATAGATGAATTACATACTATGGTAGGTGCTGGTAAAGCAGAAGGATCTATGG
ATGCTGGTAACATGCTTAAACCTGCTCTAGCTAGAGGAGAGCTAAAGTGTGTTGGTGCAACAACTTTAGATGAGTATCGT
GAGTATGTTGAAAAAGATCCGGCACTTGAGCGAAGATTCCAGAAAGTGCTAGTTGATGAACCTACTGTAGAAGATACTAT
CGCTATACTTAGAGGCCTAAAAGAAAGATATGAGCTACATCATGGTGTAAATATCACAGATTCAGCTATTGTAAGTGCAG
CAACTTTGTCACATAGGTATATCACAGATAGACAGCTACCTGATAAAGCTATAGATCTAGTAGATGAAGCAGCAAGCCAA
ATTCGTATGGAAATAGACTCTAAACCTGAAAAAATGGAAAGCTTATATCGTAGAATCATCCAGCTGAAAATGCAACGCGA
ACAGCTAAAGAAAGAGAAAGATGATGCTACTAAAAAACGTTTAGAGATACTTGAGCAAGAAATAAAAGGGCTAGACTCCG
AGTATAAAGGACTAGAAGAGCTTTGGAAAGCTGAAAAGCTTAAGATGCAAGGTACAAGTAAACTAAAAGAAGAGCTTGAG
AAAGCCAAGTTTGAACTTGAAAAGTACCAAAGAGTGGGTGATTTGAGCAAAATGGCAGAATTACAATACGGTAAAATACC
TGAGCTAGAAGCACAAATTAAACAAATAGAAGAAACTGAAGCAGAACCTTCTGAAAACAAATTAGTAAGAACATCTGTTA
CAGAAAATGAGATTGCTGATGTAGTTTCAAAAGCTACTGGAATACCTGTGTCTAAGATGATGGAAGGCGAAAAAGACAAG
CTTCTAAATATGGAAAGTTTCTTACATAAAAGAGTAATCGGACAAGATCAAGCTATAAAAGCAGTATCAAATGCTGTAAG
AAGATCTCGTTCTGGATTATCAGATCCAAATAGACCTATAGGCTCATTCATGTTCTTAGGTCCAACTGGTGTCGGTAAAA
CTGAGCTTACAAAAGCTTTAGCAGAGTTTTTGTTTGATGATGAAGATGCCATGCTTAGAGTAGATATGTCTGAGTTTATG
GAGAAACATTCTGTAGCTAGACTAATAGGCGCACCTCCTGGATACGTAGGTTATGAACAAGGCGGCTATCTAACTGAACA
TGTTAGAAGAAAACCTTATTCTGTAATCTTACTTGATGAGGTTGAAAAAGCTCATGCTGATATATTTAACATCTTACTAC
AAGTGCTTGACGATGGTCGCCTAACAGATGGGCAAGGCAGAACAGTAGACTTTAAAAATACTGTAATAGTTATGACTTCT
AACCTTGGTTCACATCGAATCCAAGAAATGCAAGGTCAGGATTATGAAACAGTAAAATCTGCTGTAATGGAAATGGTACT
TAGCCACTTTAGACCTGAATTTGTAAATAGAGTTGATGATGCAATTGTCTTTGAACCTCTAAACAAAGAGATGATAACTG
AAATAGCTAAAATACAAATCAAACGCTTAGAAAAACGTCTAGCAGATCTAAGTATAGGATTAGAAGTCACAACTGGAGCT
ATGGATAAACTAGCTGATGCTGGCTTTGATCCTGTGTTTGGTGCTAGACCGCTTAAGCGCGCTATTCAAAACAACTTAGA
AAACCCTCTGGCTCTAAAACTTCTAGATGGTGAGTTTAAAGCTGAAGATAAAATAGTTGTCGATATTGACGCTAATAACA
ATATTATATTCTCTAAATAA

Protein sequence :
MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNFIKAVNDMVDSVAVLSGEGNP
QVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDKSLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGA
LDKYTVDLTDLARKGKIDPIIGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSL
DMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLKPALARGELKCVGATTLDEYR
EYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQ
IRMEIDSKPEKMESLYRRIIQLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELE
KAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIADVVSKATGIPVSKMMEGEKDK
LLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPIGSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFM
EKHSVARLIGAPPGYVGYEQGGYLTEHVRRKPYSVILLDEVEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQIKRLEKRLADLSIGLEVTTGA
MDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFKAEDKIVVDIDANNNIIFSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-106 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_170660.1 ClpB protein VFG2076 Protein 7e-117 41