Gene Information

Name : wbtF (FTT_1459c)
Accession : YP_170396.1
Strain : Francisella tularensis SCHU S4
Genome accession: NC_006570
Putative virulence/resistance : Virulence
Product : NAD dependent epimerase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0451
EC number : 5.1.3.2
Position : 1509882 - 1510853 bp
Length : 972 bp
Strand : -
Note : Similar to Q8KN66 WbpP from Pseudomonas aeruginosa (341 aa). FASTA: opt: 1033 Z-score: 1225.7 E(): 2e-60 Smith-Waterman score: 1033; 51.562identity in 320 aa overlap

DNA sequence : 
GTGGCTTACGATAATGTTAAATTTCCTCATGGTTCGTTTTTTTTGGTGACTGGAGGTGCGGGTTTTATTGGCTCTAATTT
ATGTGAAGTTTTACTTAGTAAGGGTTATAGAGTTAGGTGTTTAGATGATCTCTCAAATGGTCACTATCACAATGTTGAGC
CGTTTTTAACTAATTCTAATTATGAGTTTATAAAAGGTGATATTAGAGATTTAGATACTTGCATGAAAGCTTGTGAAGGT
ATTGATTATGTTCTACATCAAGCTGCTTGGGGAAGCGTACCAAGAAGTATTGAGATGCCATTAGTGTATGAAGATATAAA
TGTTAAAGGTGCATTAAATATGCTTGAAGCGGCTAGACAAAATAACGTTAAAAAATTTGTCTATGCTTCTAGTTCATCAG
TATATGGTGATGAGCCAAATTTACCTAAAAAAGAAGGTAGAGAAGGAAATGTTTTATCACCCTATGCATTTACAAAGAAA
GCTAATGAAGAGTGGGCGAGACTATACACAAAGTTATATGGTCTAGATACTTATGGTCTAAGATATTTTAATGTTTTCGG
TAGAAGACAAGATCCTAATGGTGCGTATGCAGCAGTTATACCTAAATTTATCAAACAGTTATTAAATGATGAAGCGCCAA
CTATAAATGGAGATGGTAAACAGTCGAGAGATTTTACATATATAGAGAATGTTATTGAGGCAAATCTTAAAGCATGTTTA
GCAGATAGTAAGTATGCCGGAGAGTCTTTTAATATAGCTTATGGAGGTAGAGAGTATCTTATAGATTTGTACTATAATCT
TTGTGATGCCTTGGGTAAAAAAATAGAGCCAAATTTTGGTCCAGATAGAGCGGGTGATATTAAGCATAGTAATGCTGATA
TTTCGAAGGCTAGGAATATGCTCGGATATAATCCGGAATATGATTTTGAATTAGGCATAAAGCATGCTGTTGAGTGGTAT
TTAATTAATTAA

Protein sequence : 
MAYDNVKFPHGSFFLVTGGAGFIGSNLCEVLLSKGYRVRCLDDLSNGHYHNVEPFLTNSNYEFIKGDIRDLDTCMKACEG
IDYVLHQAAWGSVPRSIEMPLVYEDINVKGALNMLEAARQNNVKKFVYASSSSVYGDEPNLPKKEGREGNVLSPYAFTKK
ANEEWARLYTKLYGLDTYGLRYFNVFGRRQDPNGAYAAVIPKFIKQLLNDEAPTINGDGKQSRDFTYIENVIEANLKACL
ADSKYAGESFNIAYGGREYLIDLYYNLCDALGKKIEPNFGPDRAGDIKHSNADISKARNMLGYNPEYDFELGIKHAVEWY
LIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviC NP_458739.1 Vi polysaccharide biosynthesis protein, epimerase Virulence SPI-7 Protein 6e-62 51
tviC NP_807944.1 VI polysaccharide biosynthesis epimerase Virulence SPI-7 Protein 6e-62 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wbtF YP_170396.1 NAD dependent epimerase VFG0430 Protein 3e-62 51