Gene Information

Name : iglA1 (FTT_1359c)
Accession : YP_170311.1
Strain : Francisella tularensis SCHU S4
Genome accession: NC_006570
Putative virulence/resistance : Virulence
Product : intracellular growth locus subunit A
Function : -
COG functional category : S : Function unknown
COG ID : COG3516
EC number : -
Position : 1400818 - 1401408 bp
Length : 591 bp
Strand : -
Note : Similar to AAP58962.1 (Q7X3J5) IglA from Francisella novicida (184 aa). BLAST Score = 350, Expect = 6e-96 Identities = 181/184 (98), Positives = 181/184 (98) Identical to FTT1714. It is part of the duplicated region 1374371..1408281 which is identical to

DNA sequence : 
TTGCTTATAAGGTGTTGTGAAAAAAAGGACAATAAGATGGCAAAAAATAAAATCCCAAATTCAAGGTTGATGATAAATTA
TGAAACTAATGTTGATGGTGTCTTAAAGAAAAAAGAGCTACCTTACAGAGTCCTAGTTGTTGGCGATTTATCAAAAGGAA
GATCTGTGGATGCAAAAAAAGAGTTCGCAGATAGAGAGGTCAGAAGAGTAAATAATGGTGTTGATAGGGTTTTAGAAGAG
ATGAATATATCTTTTGATTTTGAGGCACCAAACTTTGTTTCTAAAGATCGTAGTAATTTAAAAGTTAATTATAGAATTGA
AAGTGTCAAAGATTTTAGACCTGATGCTGTTGCTAAAAAAGTTCCTGAAATCAGAGCGCTGCTTGAAATGAAAGAGATAT
TAGCATCCTTTGCTAAGGACATTGAAAATAATCGTAATCTCAAGAAAACCATAGATATGATTTTTTCAGATAGTAACGAA
TTAGAATCATTAAAGAGTAAGATTCCTGCTTTGACAAACTATACGATTAAAGACTCTTGTGATGCTGCTGAGTCTCAAGA
CTTAAGTAATCAACAAGTAGATGGTAAGTAG

Protein sequence : 
MLIRCCEKKDNKMAKNKIPNSRLMINYETNVDGVLKKKELPYRVLVVGDLSKGRSVDAKKEFADREVRRVNNGVDRVLEE
MNISFDFEAPNFVSKDRSNLKVNYRIESVKDFRPDAVAKKVPEIRALLEMKEILASFAKDIENNRNLKKTIDMIFSDSNE
LESLKSKIPALTNYTIKDSCDAAESQDLSNQQVDGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iglA1 YP_001121162.1 intracellular growth locus, igl A Virulence FPI Protein 2e-79 100
iglA2 YP_001121565.1 intracellular growth locus, iglA Virulence FPI Protein 2e-79 100
iglA1 YP_170311.1 intracellular growth locus subunit A Not tested FPI Protein 1e-85 100
iglA2 YP_170619.1 intracellular growth locus subunit A Not tested FPI Protein 1e-85 100
iglA AAP58962.1 IglA Virulence FPI Protein 6e-78 99
iglA1 YP_001891778.1 intracellular growth locus protein A Virulence FPI Protein 9e-79 99
iglA2 YP_001892273.1 intracellular growth locus protein A Virulence FPI Protein 9e-79 99