Gene Information

Name : cobS (FTT_1000c)
Accession : YP_169986.1
Strain : Francisella tularensis SCHU S4
Genome accession: NC_006570
Putative virulence/resistance : Unknown
Product : cobalamin (vitamin B12) synthesis protein/P47K family protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG0523
EC number : 2.-.-.-
Position : 1010878 - 1012104 bp
Length : 1227 bp
Strand : -
Note : Similar to Q8FUU8 Cobalamin synthesis protein/P47K family protein from Brucella suis (400 aa). FASTA: opt: 1643 Z-score: 1956.7 E(): 4.3e-101 Smith-Waterman score: 1643; 58.396 identity in 399 aa overlap.

DNA sequence :
ATGAAAAAACTACCTGTTACTGTTTTATCGGGATTTTTAGGAGCTGGTAAAACTACTTTATTAAATAATATTCTTAATAA
TGCTAATGGCCTTAGAATAGCTATGATTGTTAATGACATGAATGAAATTAATATTGATGCTGAGCTAATCAAAAATCATG
ATTCGCATATATCAAAAACTGAAGCAAAGATGGTTGAGCTTAGTAATGGCTGTATTTGCTGTACTCTGCGTGAAGATTTA
TTAGTAGAAGTAGAGCAGTTAGCAAAATCACAAAAATATGATTATTTAATTATTGAAAGTACTGGTATCTCAGAGCCTCT
ACCTGTGGCAACAACTTTTGAATTTAGAGATGAAGATGGTAAAAGCTTAGCGGATATTGCATACATTGATACAATGGTTA
CGGTAGTAGATAGTGTCAATTTTATGAATCATTATAGTTCTTCGGAATATCTAAAAAATACTAGCGAAAGCCTTGGAGAA
GATGATGATAGAGCAATAGTTGATCTTATGGTTGAGCAGATAGAGTTTGCTAATGTCATAATATTAAACAAAATTAATGA
GTGCTCGACAGCAGAAAAAGAGACTGTCAAATCTATAATCAAAGGACTAAATGTTGATGCAGAAATTATAGAAACAAATT
TTTCTAAAGTTGATATAAATAAAGTTATAAATACCAAGAAATTTAATTTAGAAGAAGCTGAAAATCATCCGTTATGGAGC
AAAGAGCTTTATAATTTCAAAGAGCATGTGCCGGAAACTGAAGAATATGGTATTAGATCTTTTGTTTATCACTCAATAAA
TCCTTTTGATCCAGTTAAGATAATGAATTTTTTTGATAATGTTGACTGGCCAGGAGTAGTGCGAGCAAAAGGCTTTTTCT
GGTTAGCTACAAGACCTGATTATGTTGGCGAGGTTTCTCAAGCAGGTGCTTTGATAAGACATCAAGGTATGGGTATGTGG
TGGGCTAGCATGGACAAAGATCAGTGGCCAGACACTCCCGAATTTAAACAAATGTTAAAAGACAGATGGAATGATATAAG
TGGTGACAGAAGGCAAGAAATAGTATTTATTGGTTTAAAAGATGAGATGAAAGATGAGCAAATTAAAGCAGCCTTGGATC
AATGCTTAATAAATGACTATTGGAATAATCCAGAAAAATATGCAAATTTAGTGGATCCATTTCCTGCTTGGTTTGAATCA
GATGATGAAGAGGTTAAAAATGAGTAA

Protein sequence :
MKKLPVTVLSGFLGAGKTTLLNNILNNANGLRIAMIVNDMNEINIDAELIKNHDSHISKTEAKMVELSNGCICCTLREDL
LVEVEQLAKSQKYDYLIIESTGISEPLPVATTFEFRDEDGKSLADIAYIDTMVTVVDSVNFMNHYSSSEYLKNTSESLGE
DDDRAIVDLMVEQIEFANVIILNKINECSTAEKETVKSIIKGLNVDAEIIETNFSKVDINKVINTKKFNLEEAENHPLWS
KELYNFKEHVPETEEYGIRSFVYHSINPFDPVKIMNFFDNVDWPGVVRAKGFFWLATRPDYVGEVSQAGALIRHQGMGMW
WASMDKDQWPDTPEFKQMLKDRWNDISGDRRQEIVFIGLKDEMKDEQIKAALDQCLINDYWNNPEKYANLVDPFPAWFES
DDEEVKNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0408 YP_042534.1 cobalamin synthesis protein Not tested vSa¥á Protein 9e-65 45
SAR0450 YP_039898.1 cobalamin synthesis protein Not tested vSa¥á Protein 5e-65 45