Gene Information

Name : megL (SPOA0318)
Accession : YP_165145.1
Strain :
Genome accession: NC_006569
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 356420 - 357622 bp
Length : 1203 bp
Strand : +
Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine

DNA sequence : 
ATGACCCATGCCAAGGGCTTTGCCAGCCGCGCCATCCACCATGCCTATGATCCGCTGGATCACGAGGGCGCGCTGACGCC
GCCGCTGCATCTGACCTCGACCTTTGCCTTCGAGACCGCCGAGGCCGGGGGCGAGATGTTCGCGGGCGAGCGTCAAGGGC
ATATCTATTCGCGCATCTCGAACCCGACGCTGGACCTGCTGGAACAGCGTATCGCCACGCTCGAAGGGGCCGAGGCGGGG
CTGGCGCTGTCCTCGGGGATGGGCGCGATCACCGCCGTTCTGTGGACGCTGTTGTCGCCCGGCGACGAGGTGATCGTGGA
CAAGACGCTCTATGGCTGCACCTTTTCCTATATGCGGCACGGGCTGGCGAAATGGGGGGTGACCATCACCCATGTGGACC
TGACCGACCCCGAGAACCTGAAAACCGCGATCAGCGACAAGACCCGCGTGGTCTATTTCGAGACGCCCGCCAACCCGAAC
ATGCGGCTGGTTGATATCGCGGCGGTAAGCGAGATTGCCCATGGCGCCAGTGCCTCGGTCGTGGTCGACAATACCTATGC
CACGCCCTACCTGACCCGGCCCATCGAGATGGGCGCCGATATCGTGCTGCATTCGGCCACCAAATATCTGGGCGGCCATG
GCGATGTGGTGGCGGGCCTTGTGGTGGGCGGTGCCGAGCAGATCAGCGAAATCCGCCTTTACGGCATGAAGGACATGACC
GGCGCGGTGATGGCCCCGTTCAACGCGATGCTGATCCTGCGCGGGCTGAAAACGCTGGCGCTGCGGATGGACCGGCATTG
CGCCTCGGCCCAGGTGGTGGCCGAATGGCTGGCCGCGCATCCGGCGGTGGGCGAGGTCCATTTCCCCGGTCTGACGTCTT
TCTCGCAGCACGCGCTGGCGAACCAGCAGATGGCCCAGCCCGGCGCGATGATCGCCTTTGAGCTCAAGGGCGGCATGGAC
GCGGGCCGGGCGATGATGAACCGTCTGAACATGATCGCGCGGGCGGTGTCGCTGGGCGATGCCGAGACGCTGATCCAGCA
TCCGGCCTCGATGACCCATTCCACCTATACGCCCGAGGAGCGGGCCGAGCATGGCATCAGCGACGGGCTGGTCCGCCTGT
CGGTGGGTCTGGAAGAGGTCGAGGATATCCTGGCCGATCTGGCCCAGTCGCTGGACGCACCCCAGGTTCAGGCCGCCGCC
TGA

Protein sequence : 
MTHAKGFASRAIHHAYDPLDHEGALTPPLHLTSTFAFETAEAGGEMFAGERQGHIYSRISNPTLDLLEQRIATLEGAEAG
LALSSGMGAITAVLWTLLSPGDEVIVDKTLYGCTFSYMRHGLAKWGVTITHVDLTDPENLKTAISDKTRVVYFETPANPN
MRLVDIAAVSEIAHGASASVVVDNTYATPYLTRPIEMGADIVLHSATKYLGGHGDVVAGLVVGGAEQISEIRLYGMKDMT
GAVMAPFNAMLILRGLKTLALRMDRHCASAQVVAEWLAAHPAVGEVHFPGLTSFSQHALANQQMAQPGAMIAFELKGGMD
AGRAMMNRLNMIARAVSLGDAETLIQHPASMTHSTYTPEERAEHGISDGLVRLSVGLEEVEDILADLAQSLDAPQVQAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-46 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_165145.1 methionine gamma-lyase BAC0207 Protein 2e-117 66