Gene Information

Name : guaA (ZMO1267)
Accession : YP_163002.1
Strain : Zymomonas mobilis ZM4
Genome accession: NC_006526
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1281103 - 1282683 bp
Length : 1581 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCGTTTCTTCAATCGCCGATAAAATTGTTTCTGAATCGATTCTCATTGTCGATTTCGGAAGCCAAGTCACCCAGCT
TATCGCTCGCCGTGTCCGTGAAGCCGGTGTATATAGCGAAATCGTCCCTTTTAACCGTGCAGAAGAAGCCTTTCAGCGCT
TGCAGCCAAAAGGTATTATCCTTTCGGGTAGTCCGGCTTCTGTTGTCGCAGAAGGCAGCCCGAGAGCGCCGGAATCCTTC
TTTCAGGCAGGTATTCCGATTTTCGGCATCTGCTATGGGCAGCAGGTTATGTGCCATCAATTGGGCGGCAAAGTTACCGC
CAATGATGTTGATGGCGAATTTGGCCGTGCCTTTATTGATGTAATCGCCCCCTCGCCTCTGTTTGAAAATTTGTGGAAGG
TCGGCGAAAAGCATCAGGTATGGATGAGCCATGCCGATCGGGTCGAGGCTTTGCCTGAAGGCTTTAAGCCTATTGCGGTT
TCTGATGGTGCGCCTTTCGCTTTGATCGCTGATGAAAAGCGCCGTTTCTATGGTATGCAATTTCATCCTGAAGTGGTGCA
TACCCCTGATGGGGGTAAGCTGATCGCTCATTTTGTCCATGACATCTGCGGTTTGGCCGGTGATTGGACGATGGCGGAAT
TTCGTCAGACAAAAATTGCTGAAATCCGCAAACAAGTCGGCGATGGTCGTGTTATTTGCGGCTTGTCTGGTGGTGTTGAT
TCTTCTGTGACTGCCGTTTTGGTGCATGAAGCTATTGGCGACCAGTTGACTTGTGTTTTTGTCGATCATGGTTTGATGCG
TCAGGGCGAAGCCGAGCAGGTCGTTTCCCTGTTCCGTGAGCATTATGGTATCAAACTGGTTCACGTGAATGCTGAAGACC
GCTTCTTGGCTGGTTTAAAGGGCGTAACTGACCCTGAAACCAAGCGAAAATTCATCGGCAAAACTTTTATCGAAATTTTT
GAAGAAGAAGCCAAAAAAATCGGTGGTGCCGACTTCCTTGCTCAAGGCACGCTTTATCCTGATGTGATCGAAAGCGTGAG
CTTCCTTGGAGGCCCGTCGGTAACGATTAAAAGCCATCACAATGTTGGTGGCCTGCCCGAACGCATGAATATGAAGCTGG
TCGAGCCGCTTCGTGAATTGTTCAAGGATGAAGTCCGCGATTTAGGGCGCGAATTGGGGATGCCTGACGTCTTCGTCGAT
CGTCATCCTTTCCCAGGTCCTGGTCTGGCTATCCGTATTCCGGGTGAAGTGACCAAGGAACGCTGCGATATTTTGCGTAA
GGCGGATGCGGTTTATCTTGAAGAAATCCGTAATGCTGGTTTGTATAATGCGATTTGGCAGGCTTTTGCGGTATTGTTAC
CCGTCAGAACCGTTGGTGTGATGGGTGACGGCAGAACTTACGATTCTGTTTGCGCCTTGCGTGCGGTGACTTCGACCGAC
GGAATGACCGCTGAAATCTATCCTTTCCAGCCGGAATTTCTTGCCAATGTCGCCACCCGTATTGTGAATGAGGTCAGAGG
CATTAACCGTGTGACCTATGATTTCACCTCTAAGCCACCCGGAACGATTGAATGGGAATAG

Protein sequence :
MSVSSIADKIVSESILIVDFGSQVTQLIARRVREAGVYSEIVPFNRAEEAFQRLQPKGIILSGSPASVVAEGSPRAPESF
FQAGIPIFGICYGQQVMCHQLGGKVTANDVDGEFGRAFIDVIAPSPLFENLWKVGEKHQVWMSHADRVEALPEGFKPIAV
SDGAPFALIADEKRRFYGMQFHPEVVHTPDGGKLIAHFVHDICGLAGDWTMAEFRQTKIAEIRKQVGDGRVICGLSGGVD
SSVTAVLVHEAIGDQLTCVFVDHGLMRQGEAEQVVSLFREHYGIKLVHVNAEDRFLAGLKGVTDPETKRKFIGKTFIEIF
EEEAKKIGGADFLAQGTLYPDVIESVSFLGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRDLGRELGMPDVFVD
RHPFPGPGLAIRIPGEVTKERCDILRKADAVYLEEIRNAGLYNAIWQAFAVLLPVRTVGVMGDGRTYDSVCALRAVTSTD
GMTAEIYPFQPEFLANVATRIVNEVRGINRVTYDFTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-128 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-128 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-116 52