Gene Information

Name : murD (ebA1447)
Accession : YP_157818.1
Strain : Aromatoleum aromaticum EbN1
Genome accession: NC_006513
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 857957 - 859357 bp
Length : 1401 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAGCGCACTGACCGGAAAACACGTTCTGGTTCTCGGGCTGGGCGAGTCCGGGCTGGCGATGGCACGCTGGTGCGCGCT
GCGCGGCGCGCGCCTGCGGGTTGCCGACAGCCGGCAGACACCTCCCGGCCTCGACACGCTGCGTGCCGATGCCCCGCTGG
CCGAGATCGTCGTCGGCAACTTTGGCGCCGAGGTGCTGAGCGGTATCGACCTGGTCGCGCTCAGTCCGGGGGTCGACCCG
CGTATCGGCATCGCCGCCGAAGCGCGCCACCGCGGATTGCCGCTCACCGGCGAAATGAGCCTGCTCGCCCAGGCGCTCGA
CGAACTCGGGGTGCGTGCGCAGACTCGCATCCTTGCGATCACCGGCACGAACGGCAAGACCACCACTACCGCGCTCACCG
CGGCTCTCGCGCAAGCGGCAGGGCTGGACGCGGTGGCGGCGGGCAACATCAGCCCGGCCGCTCTCGACGTGCTGATGGAC
AGGCTGGCACAGGGCGCACCGCTGCCCGAATGCTGGGTGCTCGAGCTGTCGAGCTTCCAGATCGAGACGATGCATGCGCT
CGATCCCGAAGCCGCGACAGTGCTCAACGTCACCGATGACCATCTCGATCGCTATGCCGGCCTCGACGAATACGCTGCCA
CCAAGGCCGCGATCTTCGAGGGCCGCGGCGTGCAGGTGCTCAACCGCGACGACGCACGGGTGGCGGCGATGGCCTTGCCC
GGACGCTCGCTGATCCGGTTCGGCGCTTCGGCGCCGGCGGCGACGGACGACTACGGGCTCGTGGAGGTCGCCGGCGCAGC
GTGGCTGGTGCGCGGCCGGGAGCGCCTGCTCGCGCTGGCCGACCTGCCTCTTGCCGGCAGGCACAACGCCGCCAATACGC
TGGCCGCGCTGGCCTTGTGCGAAGGCGGCCTGGGCATCGCGCCGCAACGCCTGACAGGCGCTGTCGTCGCGTTTCGCGGC
CTGCCGCACCGGGTCGAGCTGGTCGCCGAGCGCAGCGACGGCGTGCGCTTCTATGACGACTCCAAAGGTACCAACGTCGG
CGCTACCGTGGCTGCGCTCGACGGGATGGACTGCCCGGTCGTGCTGATCGCCGGCGGCGACGGCAAGGGGCAGGATTTTT
CGCCGCTGCGCGAAGCCGTTGTGCGCCGTGCGCGGGCGGTGGTGCTGATCGGGCGGGATGCCCCGCGCATCGAGTCCGCG
CTGCAAGGGTCGGCCGTCGCGCTCGAACATGCACCCGATCTCGATGCCGCCGTCGTTCGCGCCAGCGAGCAGGCGCAGCC
CGGCGACGCGGTGCTGCTGTCGCCCGCCTGCGCGAGCCTCGACATGTTCCGCAACTACGCGCATCGCGCCGAAGTGTTCA
TCGCCGCGGCACGGCGGCTGCCGGAGGTGCGCGCGTCATGA

Protein sequence :
MSALTGKHVLVLGLGESGLAMARWCALRGARLRVADSRQTPPGLDTLRADAPLAEIVVGNFGAEVLSGIDLVALSPGVDP
RIGIAAEARHRGLPLTGEMSLLAQALDELGVRAQTRILAITGTNGKTTTTALTAALAQAAGLDAVAAGNISPAALDVLMD
RLAQGAPLPECWVLELSSFQIETMHALDPEAATVLNVTDDHLDRYAGLDEYAATKAAIFEGRGVQVLNRDDARVAAMALP
GRSLIRFGASAPAATDDYGLVEVAGAAWLVRGRERLLALADLPLAGRHNAANTLAALALCEGGLGIAPQRLTGAVVAFRG
LPHRVELVAERSDGVRFYDDSKGTNVGATVAALDGMDCPVVLIAGGDGKGQDFSPLREAVVRRARAVVLIGRDAPRIESA
LQGSAVALEHAPDLDAAVVRASEQAQPGDAVLLSPACASLDMFRNYAHRAEVFIAAARRLPEVRAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 3e-49 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 3e-49 42