Gene Information

Name : hemC (ebA1166)
Accession : YP_157636.1
Strain : Aromatoleum aromaticum EbN1
Genome accession: NC_006513
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 676229 - 677173 bp
Length : 945 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
GTGAGCGCTACCCCTGACTTTCCCGCCCCCGAACGCCTCGTAATCGCCACTCGCGAAAGCCGTCTAGCACTGTGGCAGGC
CGAACACGTCAAGGCTCGGCTCGAGGCGCTCTACCCGGGCTGTCGCGTCGAGCTGCTCGGCATGACCACGCGCGGCGACC
AGATCCTCGACCGTCCGCTCGCGAAGGTCGGCGGCAAGGGGCTGTTCGTCAAGGAACTCGAAGCCGCGCTGCTCGAGGAG
CGCGCCGACATCGCGGTGCATTCGATGAAGGACGTGCCGATGCAGCTGGCCGAACCGTTCGCGCTGCCGTGCATCTCGGC
GCGCGAAGTGCCGCTCGACGCGTTTGTGTCGCCGCGCTACGCGAGCCTCGCCGACATGCCGCCGGGCACGGTCGTCGGCA
CGTCATCGCTGCGCCGCGAATCGCAGCTGCATGCGCAGTTCCCGTTCCTGGCGGTCACGAGCCTGCGCGGCAACCTCGAC
ACGCGCCTGCGCAAGCTCGACGAGGGGCAGTACGACGCGATCATTCTCGCCGCCGCCGGACTGCGGCGCTTAGGGCTTGC
CGACCGCATCCGTGCCGAACTGCCGTCCGAGGTGTCGCTGCCGGCGGCCGGGCAGGGCGCGCTCGGCATCGAATGCCTGG
CGAAGCGCACCGACATCGCGGCCTGGCTCGCGCCGTTGAACGATGCCGACACTTCCGCGTGCGTGCGCGCCGAGCGCGCC
GTCGCGCGCGCGCTCGCGGGCAGCTGCGAAGTGCCGCTCGGCGCCTACGCCGAGATCCGCGCCGGCCGGCTGTGGCTGCG
CGGTTTCGTCGCGCTGCCCGATGGCAGCCGCATGGTCCGCGCCGAACGCGAAGGCGATGCCGCCGATGCCGAAGGGCTCG
GCCTCGCACTGGCCGACGACTTGCGCGCGCAAGGGGCCGAAGACATCCTCGCGCGGCTGGGGTGA

Protein sequence :
MSATPDFPAPERLVIATRESRLALWQAEHVKARLEALYPGCRVELLGMTTRGDQILDRPLAKVGGKGLFVKELEAALLEE
RADIAVHSMKDVPMQLAEPFALPCISAREVPLDAFVSPRYASLADMPPGTVVGTSSLRRESQLHAQFPFLAVTSLRGNLD
TRLRKLDEGQYDAIILAAAGLRRLGLADRIRAELPSEVSLPAAGQGALGIECLAKRTDIAAWLAPLNDADTSACVRAERA
VARALAGSCEVPLGAYAEIRAGRLWLRGFVALPDGSRMVRAEREGDAADAEGLGLALADDLRAQGAEDILARLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-47 59
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-47 59