Gene Information

Name : kdsB (ebA5086)
Accession : YP_159908.1
Strain : Aromatoleum aromaticum EbN1
Genome accession: NC_006513
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3014086 - 3014862 bp
Length : 777 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGGCCGCGTTCCACGTCGTCATCCCGGCGCGCCACGCGTCGAGCCGGCTTCCGGGCAAGCCGCTCGCCGACATCGCCGG
CAAGCCGATGGTCGTGCGCGTGCTCGAGCAGGCGCGCCGCGCCGGCGCCGCGTCGGTGTGGGTCGCCACCGATCACCCGG
AGGTGCTCGACGCGGTCAGGGCGGCCGGCGGCGACGCGCTGATGACGCGGGAAGATCATCCGAGCGGCACGGATCGGCTC
GCCGAAGTCGTCGACGCGCTCGGCTGGAAAGCGGACGACATCGTCGTCAACGTCCAGGGCGACGAACCGCTGATCGAGCC
GAAGCTGATCGCGGCGGTCGCGCAGGCGCTCGCCGACGACCCGGTCGCGGCGATCGCGACCGCCGCCCACCCGCTGCACG
CCGCCGCCGAGTTGTTCAACCCGAACGTCGTCAAGGTCGTCTGCGATGCGCACGATCACGCGCTGTATTTTTCGCGCGCC
CCGATCCCGTGGGCGCGCGATGCGTTCGCCACTGCCCGCGACGATATTCCCGCCGGCCTGCCGGTGCTGCGTCACGTCGG
CCTGTACGCGTACCGCGTCGCGTTCCTGCGCTGCTACGCGAGCCTCGCTCCGTCGCCGCTCGAGCAATGGGAAGCGCTCG
AACAGTTGCGCGCGCTGTGGCACGGACACCGGATCCGGGTGATGACCGTCGCGGTCGCGCCGGCAGCGGGCGTCGACACG
CCCGAAGACCTCGAGCGCGTGCGGGCGGCGTTTGACCGGCATGAACGAGTCGGTTAA

Protein sequence : 
MAAFHVVIPARHASSRLPGKPLADIAGKPMVVRVLEQARRAGAASVWVATDHPEVLDAVRAAGGDALMTREDHPSGTDRL
AEVVDALGWKADDIVVNVQGDEPLIEPKLIAAVAQALADDPVAAIATAAHPLHAAAELFNPNVVKVVCDAHDHALYFSRA
PIPWARDAFATARDDIPAGLPVLRHVGLYAYRVAFLRCYASLAPSPLEQWEALEQLRALWHGHRIRVMTVAVAPAAGVDT
PEDLERVRAAFDRHERVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 5e-37 50
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-37 50
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-37 50