Gene Information

Name : thyA (ebA4415)
Accession : YP_159532.1
Strain : Aromatoleum aromaticum EbN1
Genome accession: NC_006513
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2619774 - 2620568 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCTCGACCTGATGCGCCATGTCCTCGATCATGGCGACCGGAAATCCGACCGGACCGGCACCGGCACACT
TTCGATCTTCGGTTGGCAGATGCGGTTTAATCTCGACGACGGCTTTCCTCTGCTCACGACGAAGAAACTGCACACCCGTT
CGATAATTCACGAATTGCTGTGGTTTCTGCGCGGCGATACCAATATCCGCTACCTCAACGAGAATGGCGTGTCGATCTGG
GACGACTGGGCCGACGAGAATGGCGATCTCGGGCCGGTGTACGGCAAGCAATGGCGCCGCTGGGAGACGGCAAACGGCGC
CACTATCGACCAGATCGCACAACTGATCGACGGACTGAAGCACAATCCTGATTCGCGCCGCCATCTGGTTTCAGCGTGGA
ATCCGGGAGAAGTGGCCGGAATGGCGCTTCCCCCGTGTCACGCACTGTTCCAGTTCTATGTTGCGGGTGACCGACTGTCC
TGCCAGTTGTACCAACGCAGTGCCGACATCTTCCTCGGAGTACCGTTCAACATTGCGTCCTACGCGCTACTGACACTGAT
GGTGGCTCAGGTCTGCGGGCTGCGGGCCGGGGATTTCGTATGGACAGGGGGGGATTGCCACCTGTACCTCAACCATCTCG
ATCAGGCACGTCTGCAGCTCTCCCGGCAACCACGCGCTTTGCCGCGGATGATCGTGAATCCCGGCGTCACCGACATCTTT
GGATTCCGCTTCGAAGATTTTCGTCTCGAAGGCTATGACCCCCACCCCCATATCAAAGCGGAAGTGGCCGTATGA

Protein sequence :
MKQYLDLMRHVLDHGDRKSDRTGTGTLSIFGWQMRFNLDDGFPLLTTKKLHTRSIIHELLWFLRGDTNIRYLNENGVSIW
DDWADENGDLGPVYGKQWRRWETANGATIDQIAQLIDGLKHNPDSRRHLVSAWNPGEVAGMALPPCHALFQFYVAGDRLS
CQLYQRSADIFLGVPFNIASYALLTLMVAQVCGLRAGDFVWTGGDCHLYLNHLDQARLQLSRQPRALPRMIVNPGVTDIF
GFRFEDFRLEGYDPHPHIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-82 62