Gene Information

Name : topB1 (ebA2458)
Accession : YP_158408.1
Strain : Aromatoleum aromaticum EbN1
Genome accession: NC_006513
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1478515 - 1480536 bp
Length : 2022 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGCGTGTTCCTGTGCGAGAAGCCTTCGCAAGGCAAGGACATCGCCCGCGTGCTGGGCGCGGGCCAGCGTCGTAATGG
CTGCTACAGCGGCGCCGGCATCGTCGTGACCTGGTGCATCGGTCATCTGGTGGAAGCGGTTCCGCCCGAGGGTTATGACG
AGCGCGATAAGCGTTGGGTCATCGAGCAGCTGCCCATCATTCCCGAGCGCTGGCGCGTCGAGCCCAAGGCTGCGACCGCC
GCGCAATTCAAGATCGTCAAGCAACTCGTCGGTCAGGCCACCGAGTTGGTGATCGCCACCGATGCTGATCGCGAGGGCGA
GATGATCGCCCGCGAGATCATCGAGCTGTGCGGCTACCGCGGGGCAATTCAGCGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCGATCCGCAAGGCACTGGGCGCGCTGAAGTCCTCCGCCGAAACGCTGCCGCTGTACTACTCGGCCCTGGCCCGCTCG
CGCGCCGACTGGCTGATCGGCATGAACCTGAGTCGGCTGTTCACGCTGCTCGGGCGACAGGCCGGCTACACCGGCGTGCT
GTCGGTGGGCCGGGTGCAGACGCCGACGCTGAAACTGGTGGTGGATCGCGACCGCGAAATCGCGCGATTTGTCTCGGCGC
CGTTCTGGGCCGTCGAGGTGGCGCTGTCCCATGCGGGGCAGCCCTTCACGGCGAGCTGGACGCCGCCGGAAGGCTGTACC
GACGAGGCCGGCCGCTGCCTGCAACAGCCGGTGGCCCAGCAGGCTGCCGAGCGCATGCGTGCTACTGGCAGCGCCCAGGT
GGCGTCGGTCGAGACGGAGCGCGTGCGCGAAGGTCCGCCGCTGCCATTCGACCTGGGCACGCTGCAGGAGTTGTGTTCCC
AGCAGTTGGGCCTGGACGTGCAGGAGACGCTGGACATCGCCCAGGCGCTGTACGAGACGCACAAGGCGACGACCTACCCG
CGCTCCGACTCGGGCTACCTGCCCGAGAGCATGCTCGCGGAGGTGCCGACCGTTCTCGACAGCCTGGTCAAGACCGATCC
CAGCCTGCGCCCGTTGATCGATCGCCTGGACCGCAATCAGCGCTCGCGCGCCTGGAGCGACGCCAAGGTCACGGCCCACC
ACGGCATCATCCCGACGTTGGAGCCCGCCAATCTCTCCGCGATGAACGACAAGGAGCTGGCCGTCTACAAACTGATCCGC
GCGCATTACCTGGCGCAGTTCCTGCCACATCACGAGTTCGACCGGACGGTGGCGGAGCTCGCTTGCGGCGGGCAGTCGCT
GCTGGCCGTCGGCAAGCAGATCGCCGTGGCCGGCTGGCGTCAGGTGCTGGCGTCATCGGAGGAAGGCGGGGCGGATAGCG
ATGACGCGCAGCGCAGTCAGGTTCTGCCGGCGTTGCGAGCCGGCTTGTCCTGCCAGGTCGGTCACGTAGACCTGAAGGCG
CTGAAGACCCTGCCGCCCAAGCCCTACACCCAGGGCGAACTGGTCAAGGCCATGAAGGGCGTCGCCAGGCTCGTTACCGA
CCCGCGCTTGAAGCAGAAGCTCAAGGACACGACGGGCATCGGCACCGAGGCCACGCGCGCCAACATCATCAGCGGCCTGC
TCGGCCGCGGTTATCTGCTGACGAAGGGCCGCGCCGTCCGCGCGTCGGATGCAGCTTTCACACTGATCGACACCGTGCCG
GCGGCCATCGCCGATCCGGGCACGACGGCGGTCTGGGAGCAGGCGCTGGACATGATCGAGGCAGGCCAGATGACACTGGA
CGCCTTCATCGCCAAGCAATCCGCCTGGGTGACCCAACTCGTGCAGCAGTACCGCGGCACAACGCTCGCCATCAAGCTGC
CGCCATCGCCATCGCCATCCTGCCCGCAGTGCGGCGCGCCGATGCGTCAGCGCACGGGCAAGAGCGGCGCTTTCTGGTCA
TGCAGCCGCTACCCGGACTGCAAGGGCACGCTGCCGGTCGACACCTCGACAGGCAAGCGCAGTGCATCGCGCAAGCAGCG
CGCTTCCCCCAAGGCGTCCTGA

Protein sequence :
MRVFLCEKPSQGKDIARVLGAGQRRNGCYSGAGIVVTWCIGHLVEAVPPEGYDERDKRWVIEQLPIIPERWRVEPKAATA
AQFKIVKQLVGQATELVIATDADREGEMIAREIIELCGYRGAIQRLWLSALNDASIRKALGALKSSAETLPLYYSALARS
RADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVSAPFWAVEVALSHAGQPFTASWTPPEGCT
DEAGRCLQQPVAQQAAERMRATGSAQVASVETERVREGPPLPFDLGTLQELCSQQLGLDVQETLDIAQALYETHKATTYP
RSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIDRLDRNQRSRAWSDAKVTAHHGIIPTLEPANLSAMNDKELAVYKLIR
AHYLAQFLPHHEFDRTVAELACGGQSLLAVGKQIAVAGWRQVLASSEEGGADSDDAQRSQVLPALRAGLSCQVGHVDLKA
LKTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIISGLLGRGYLLTKGRAVRASDAAFTLIDTVP
AAIADPGTTAVWEQALDMIEAGQMTLDAFIAKQSAWVTQLVQQYRGTTLAIKLPPSPSPSCPQCGAPMRQRTGKSGAFWS
CSRYPDCKGTLPVDTSTGKRSASRKQRASPKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 79
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 77
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 64
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-169 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 2e-160 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 1e-160 50
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 2e-160 50
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 3e-166 49