Gene Information

Name : lysS (IL0822)
Accession : YP_155211.1
Strain : Idiomarina loihiensis L2TR
Genome accession: NC_006512
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 877140 - 878651 bp
Length : 1512 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACTGATAAATCGCAGGCACCTGAAGTAGACGTAAACGAACAGATCGCGCAGCGAAAGGCGAAACTGTCGGCGCTTCG
CGATAAGGGTATCGCATTCCCGAACGATTTCCGTCGGGACTCGTTAGCTGCTGACTTACACGCTGAATACGATAATCTGA
GCAAAGAAGAGCTGGCGGAAAAAGGCATTCGCGTGAAAGTTGCCGGCCGTATGATGACCCGCCGTATTATGGGGAAAGCC
AGTTTCGCAACCATCCAGGATATGAGCGGCAAAATTCAACTGTATGTTGCCCGCGACAATCTGCCTGAAGGTTATTACAA
CACGGAATTTAAAAAATGGGATTTAGGCGATATTCTCGGCGCCTCTGGCACCTTGTTTATTACCGGAACCGGTGAGTTAA
GCGTGCAAGTTGACGAAGTACGTTTGCTGACTAAAGCACTGCGTCCTTTGCCGGATAAATTCCATGGCTTGTCAGATCAG
GAAATGCGCTATCGTCAGCGTTATCTGGACCTGATTACCAACGAAGAGTCTCGCAGTACTTTCATGGCTCGCTCTAAAAT
CATTGACTATATTCGTCGTTTTTTAAGTGACCGTCAGTTTCTGGAAGTTGAAACTCCTATGATGCAGGCGATTCCGGGCG
GCGCCGCAGCTCGTCCTTTCAGCACGCACCATAACGCACTGGATATGGAACTGTTTTTACGTATTGCACCAGAACTTTAC
CTGAAACGTTTAGTCGTTGGTGGTTTTGAGAAGGTGTTCGAAATTAACCGTAATTTCCGTAATGAAGGCCTGTCAACGCG
CCACAACCCTGAGTTCACTATGTTGGAGTTCTACTGGGCGTACGCGGATTATCACGACTTAATGGATTTAACCGAGCAGA
TGTTACGTGGTGCGGCTGAGTCGGTCTTAGGCTCTGCTCAGTTTACCAGCCAGGGCGTGGATTATGATTTCGGTAAGCCG
TTTGAGCGCATGACAGTGTTGGAAGCTATTGTTAAGTACATGCCGGAAGTGAGCCTTGAGCAGCTTAATGACATGAATAC
AGCAACTGAAATTGCCGAGCAGGTTGGTGTCAGTGTTAAGCCGTCATGGGGCTTAGGTAAAGTTCAGATCGAAATTTTTG
AGACTGTTGCTGAGCATCGTTTAATTCAGCCTACCTTTATTACTGCGTACCCGGCTGAAGTTTCACCGTTGGCTCGTCGT
CACGACGACAATCCGTTTGTGACTGATCGTTTTGAATTTTTTGCCGGTGGTCGTGAGTTGGCGAATGGTTTCTCGGAGCT
TAACGATGCTGAAGATCAGGCTGAACGTTTTCGCGAGCAAGTTGAACAGAAAGAAGCGGGCGATGATGAAGCCATGTTCT
ACGACGAAGATTATGTCACCGCACTGGAACACGGTATGCCGCCAACAGCCGGTCAGGGCATTGGTATTGACCGTCTGGTA
ATGTTGCTAACGGATTCTGCGTCTATTCGCGACGTATTATTGTTCCCGCATATGCGCCCAAAAGCGGATTAA

Protein sequence :
MTDKSQAPEVDVNEQIAQRKAKLSALRDKGIAFPNDFRRDSLAADLHAEYDNLSKEELAEKGIRVKVAGRMMTRRIMGKA
SFATIQDMSGKIQLYVARDNLPEGYYNTEFKKWDLGDILGASGTLFITGTGELSVQVDEVRLLTKALRPLPDKFHGLSDQ
EMRYRQRYLDLITNEESRSTFMARSKIIDYIRRFLSDRQFLEVETPMMQAIPGGAAARPFSTHHNALDMELFLRIAPELY
LKRLVVGGFEKVFEINRNFRNEGLSTRHNPEFTMLEFYWAYADYHDLMDLTEQMLRGAAESVLGSAQFTSQGVDYDFGKP
FERMTVLEAIVKYMPEVSLEQLNDMNTATEIAEQVGVSVKPSWGLGKVQIEIFETVAEHRLIQPTFITAYPAEVSPLARR
HDDNPFVTDRFEFFAGGRELANGFSELNDAEDQAERFREQVEQKEAGDDEAMFYDEDYVTALEHGMPPTAGQGIGIDRLV
MLLTDSASIRDVLLFPHMRPKAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-155 61
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-88 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_155211.1 lysyl-tRNA synthetase VFG1668 Protein 3e-155 61