Gene Information

Name : guaA (IL0579)
Accession : YP_154969.1
Strain : Idiomarina loihiensis L2TR
Genome accession: NC_006512
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 613325 - 614902 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTAGAGATATCCACGACCACCGAATATTGATTCTGGATTTCGGCTCTCAGTACACTCAGCTGATAGCCCGCCGCAT
TCGCGAAATTGGCGTTTACTGTGAACTTTGGGCCTGGGATGTTGACGAAGCTGACATCCGCGAATTTGCGCCTAAAGGCA
TTATTTTATCGGGTGGCCCGGAAAGCGTAGCTGAAGAGGGTTCGCCGCGTGCGCCTGAATATGTCTTTAACGCAGGCGTA
CCAGTATTTGGTATTTGCTACGGCATGCAGACCATGGCACATCAGCTGGGTGGTTCGGTGCAATGCTCGCTGGAGCGCGA
ATTCGGTTACGCGCAAATTGAGCTGGTAGAGCAAAGCCCGCTGTTTAAAGCTATTGAAGACGCTGTGTCTGAGTCTGGTG
CGCCGTTACTGGATGTGTGGATGAGCCACGGTGACAAAGTGGAAATGATTCCGGAAGGCTTTCACACCGTAGCGAAAACC
TCCTATTGCCCGTATGCCGCAATGGCTGACGAAGAACGCCAGTTTTATGGTGTGCAGTTTCACCCGGAAGTGACTCATAC
GCGGCAGGGACAGCGTATGCTGGAGCATTTTGTCAGCGATATCTGCGGTTGTGAGAAGCAATGGACGCCGGCAAAAATCA
TTGATGACGCCATTGAGCGCATCCGTGAACAGGTAGGTAGTGACAAGGTTATTCTTGGTTTGTCTGGCGGTGTTGATTCG
TCGGTAACGGCTATGCTGCTGCACCGGGCTATTGGCGAGCAGCTGACCTGCGTATTTGTCGACAACGGATTGCTGCGGCT
GAACGAAGCTGAGCAGGTGATGGAAATGTTCGGCGACCACTATGGTCTGAACATTTTGCCAATACGTGCAGAAGACCGCT
TCTTAGATGCGTTGGCGGGTGAGAATGACCCGGAGAAAAAGCGTAAAATTATTGGTAATACCTTCATTGAAATTTTTGAT
GAAGAAGCCGGTAAGCTGACCGAGGTTGACTGGCTGGCGCAGGGCACTATTTACCCTGACGTAATTGAGTCCGCTGGTTC
TAAAACCGGTAAAGCGCACGTGATTAAATCACATCACAACGTGGGCGGTTTGCCGGAAGACATGAAGTTAGGTTTGGTTG
AGCCACTGCGTGAATTGTTTAAAGACGAAGTGCGTAAAATTGGGCTTGAGTTAGGCCTGCCGTACAACATGCTTTACCGT
CATCCGTTCCCGGGACCTGGTTTGGGTGTTCGTGTGCTGGGTGAAATTAAGAAAGAATACTGCGACTTATTGCGCCGTGC
CGATGCGATTTTCATTGAAGAGCTGCACAACGCGGACTGGTACAACAAAGTCAGCCAGGCCTTTGCGGTATTCCTGCCGG
TACGTTCGGTGGGTGTTATGGGTGATCAGCGTAAATACGACTGGGTTATTGCCATACGCGCCGTAGAGACTATCGACTTT
ATGACCGCGCGCTGGGCTCATTTGCCGTATGAGTTGCTAGAGAAGGTATCAAACCGGATTATCAACGAAGTTAACGGAAT
TTCCCGCGTAACCTACGATATTTCAGGTAAACCACCTGCCACCATCGAGTGGGAATAA

Protein sequence :
MTRDIHDHRILILDFGSQYTQLIARRIREIGVYCELWAWDVDEADIREFAPKGIILSGGPESVAEEGSPRAPEYVFNAGV
PVFGICYGMQTMAHQLGGSVQCSLEREFGYAQIELVEQSPLFKAIEDAVSESGAPLLDVWMSHGDKVEMIPEGFHTVAKT
SYCPYAAMADEERQFYGVQFHPEVTHTRQGQRMLEHFVSDICGCEKQWTPAKIIDDAIERIREQVGSDKVILGLSGGVDS
SVTAMLLHRAIGEQLTCVFVDNGLLRLNEAEQVMEMFGDHYGLNILPIRAEDRFLDALAGENDPEKKRKIIGNTFIEIFD
EEAGKLTEVDWLAQGTIYPDVIESAGSKTGKAHVIKSHHNVGGLPEDMKLGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEIKKEYCDLLRRADAIFIEELHNADWYNKVSQAFAVFLPVRSVGVMGDQRKYDWVIAIRAVETIDF
MTARWAHLPYELLEKVSNRIINEVNGISRVTYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-130 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-130 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-130 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-112 48