Gene Information

Name : kdsB (IL1510)
Accession : YP_155897.1
Strain : Idiomarina loihiensis L2TR
Genome accession: NC_006512
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1620228 - 1620989 bp
Length : 762 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTACCGTTGTCATTCCAGCTCGCTACGGTTCCAGCCGCTTGCCGGGCAAACCTTTAGCCGATATTGCCGGAAA
GCCGATGATTCAGCATGTGGTTGAGCGAGCTGAGGCTAGTGGCGCTGCCGAAGTCATAGTTGCTACCGATGATATGCGGA
TTAAAGAGGGCGTTGATAAGTTTGGTGGTCGCGTAATGATGACCTCAAGTGAGCACTCCTCGGGTACGGAACGTTTGGCT
GAAGTTATCGAACAATTAGCTCTGGCAGAAAACGAGGTGGTGGTTAATGTTCAGGGTGATGAGCCCTTTATTCCGCCTGA
AATTATTCGACAGGTTGCCGATAACTTAGCGAATCAACGGCAGGCACCTATGGCGACGCTGGCCGTGCCCATTACTGACG
CTGAAGATATTTTTAACCCGAATACAGTAAAAGTGGTTACCGATGCTGCGGGTTATGCGCTGTACTTTAGCCGTGCCGCA
ATTCCCTGGGACAGAGAGCACTTTTCTGCCGACCGGGCGACAAATGTCGTTACTGAGCATTATCATCGTCACATTGGTAT
TTATGCTTATCGGGCGGGTTTTGTCAGACGTTATATTGAATGGGAGCCAAGCCCTATTGAACAGCTTGAGTCGTTAGAAC
AATTGCGGGTGCTTTGGCACGGAGAACGTATTCATGTCGCTGAAGCCATTCTCGCACCGGCTACAGGCATTGATACTGAA
GAGGACCTGCAGCGGGCACGAAAACTGGCAGGCGATGGTTAA

Protein sequence :
MSFTVVIPARYGSSRLPGKPLADIAGKPMIQHVVERAEASGAAEVIVATDDMRIKEGVDKFGGRVMMTSSEHSSGTERLA
EVIEQLALAENEVVVNVQGDEPFIPPEIIRQVADNLANQRQAPMATLAVPITDAEDIFNPNTVKVVTDAAGYALYFSRAA
IPWDREHFSADRATNVVTEHYHRHIGIYAYRAGFVRRYIEWEPSPIEQLESLEQLRVLWHGERIHVAEAILAPATGIDTE
EDLQRARKLAGDG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-42 47
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 9e-43 47
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 8e-43 47