Gene Information

Name : prgK (SPA2729)
Accession : YP_151898.1
Strain : Salmonella enterica ATCC 9150
Genome accession: NC_006511
Putative virulence/resistance : Virulence
Product : pathogenicity 1 island effector protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4669
EC number : -
Position : 2829542 - 2830300 bp
Length : 759 bp
Strand : -
Note : similar to Salmonella typhi CT18 pathogenicity 1 island effector protein

DNA sequence :
ATGATTCGTCGATATCTATATACTTTTCTGCTGGTAATGACCCTTGCCGGCTGTAAGGATAAGGATCTTTTAAAAGGACT
GGACCAGGAACAGGCTAATGAGGTCATTGCCGTTCTGCAAATGCACAATATAGAGGCGAATAAAATTGATAGCGGAAAAT
TGGGCTATAGCATTACCGTTGCTGAGCCTGATTTTACCGCTGCGGTGTACTGGATTAAAACTTATCAGCTTCCTCCCCGG
CCACGGGTGGAAATAGCGCAGATGTTCCCGGCGGATTCGCTGGTATCGTCTCCGCGAGCTGAAAAGGCCAGGTTATATTC
GGCTATTGAACAGCGACTGGAACAGTCATTACAGACGATGGAGGGCGTGCTCTCCGCCAGGGTCCATATTAGTTATGATA
TTGATGCTGGTGAAAATGGCCGCCCGCCAAAACCTGTTCATCTGTCGGCATTAGCCGTATATGAACGAGGTTCGCCGCTT
GCGCATCAGATCAGCGATATCAAGCGTTTCTTAAAGAATAGTTTTGCCGATGTGGATTATGACAACATTTCTGTTGTGTT
GTCAGAACGTTCTGATGCCCAATTACAGGCTCCCGGCACACCAGTAAAACGTAATTCTTTTGCAACCAGTTGGATTGTGT
TGATTATTTTGTTATCCGTGATGTCAGCAGGCTTTGGCGTCTGGTATTACAAAAACCATTATGCCCGCAATAAGAAAGGC
ATAACGGCTGATGATAAGGCGAAATCGTCAAATGAATAG

Protein sequence :
MIRRYLYTFLLVMTLAGCKDKDLLKGLDQEQANEVIAVLQMHNIEANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPR
PRVEIAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALAVYERGSPL
AHQISDIKRFLKNSFADVDYDNISVVLSERSDAQLQAPGTPVKRNSFATSWIVLIILLSVMSAGFGVWYYKNHYARNKKG
ITADDKAKSSNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prgK YP_217790.1 cell invasion protein Virulence SPI-1 Protein 3e-116 100
prgK NP_461792.1 needle complex inner membrane lipoprotein Virulence SPI-1 Protein 3e-116 100
prgK NP_806474.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 3e-115 99
prgK NP_457265.1 pathogenicity 1 island effector protein Virulence SPI-1 Protein 3e-115 99
prgK AAS66872.1 PrgK Virulence SSR-2 Protein 5e-57 58
ECs3716 NP_311743.1 EprK Not tested LIM Protein 3e-54 56
eprK AAZ31284.1 EprK Virulence ETT2 Protein 3e-53 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
prgK YP_151898.1 pathogenicity 1 island effector protein VFG0533 Protein 1e-116 100
prgK YP_151898.1 pathogenicity 1 island effector protein VFG0998 Protein 3e-45 47
prgK YP_151898.1 pathogenicity 1 island effector protein VFG1787 Protein 2e-37 46