Gene Information

Name : spiA (SPA1459)
Accession : YP_150710.1
Strain : Salmonella enterica ATCC 9150
Genome accession: NC_006511
Putative virulence/resistance : Virulence
Product : outer membrane secretory protein
Function : -
COG functional category : N : Cell motility
COG ID : COG1450
EC number : -
Position : 1530402 - 1531895 bp
Length : 1494 bp
Strand : -
Note : similar to Salmonella typhi Ty2 putative outer membrane secretory protein

DNA sequence :
ATGGTAGTAAATAAACGTTTAATCTTAATTTTACTATTTATACTCAATACGGCAAAGAGTGATGAGTTATCATGGAAAGG
TAATGACTTCACCCTTTATGCCAGACAAATGCCATTAGCAGAGGTTTTACATCTGCTCTCAGAGAACTATGATACGGCTA
TTACTATTAGCCCATTGATAACAGCTACATTTAGTGGGAAAATTCCGCCTGGACCACCGGTCGATATTTTGAATAACCTG
GCAGCACAATATGATTTGCTTACCTGGTTTGATGGCAGCATGTTATATGTATATCCTGCATCGTTATTAAAACATCAGGT
TATCACTTTTAATATTTTATCTACTGGACGGTTCATTCATTACTTACGCAGCCAGAATATCCTTTCATCACCGGGATGCG
AGGTTAAAGAAATTACCGGTACCAAAGCTGTGGAGGTGAGCGGTGTTCCCAGTTGCCTGACTCGTATTAGTCAATTAGCT
TCGGTGTTGGATAATGCGTTAATCAAACGAAAAGACAGTGCGGTGAGTGTAAGTATATACACGCTTAAGTATGCCACTGC
GATGGATACCCAATACCAATATCGCGATCAGTCCGTCGTGGTTCCAGGGGTCGTGAGTGTATTGCGTGAGATGAGTAAAA
CCAGCGTACCGGCGTCATCGACGACCAATGGTTCACCCGCTACACAGGCATTGCCCATGTTTGCTGCCGACCCACGCCAG
AATGCAGTGATCGTTCGTGATTATGCGGCCAATATGGCCGGGTATCGGAAACTTATCACAGAATTAGATCAACGCCAGCA
GATGATAGAGATTTCGGTGAAAATTATCGATGTTAATGCTGGAGATATTAACCAGTTAGGCATCGACTGGGGAACGGCAG
TGTCGCTGGGTGGCAAGAAAATTGCGTTCAATACAGGTTTGAATGACGGTGGTGCTAGCGGTTTTTCAACGGTAATCAGC
GATACCTCAAACTTTATGGTGCGTTTGAATGCCCTGGAAAAAAGCTCTCAGGCTTATGTACTTTCCCAGCCATCTGTGGT
GACTTTAAATAATATCCAGGCTGTGCTGGATAAAAATATTACTTTCTATACCAAACTGCAGGGAGAAAAAGTGGCTAAAC
TTGAATCCATCACTACGGGTTCTTTGTTGCGCGTTACACCTCGCTTGTTAAATGACAATGGCACGCAAAAAATAATGCTT
AATCTTAATATTCAGGATGGACAACAAAGTGATACGCAAAGCGAAACAGATCCGCTACCCGAAGTGCAAAATTCTGAAAT
TGCTTCGCAAGCCACATTATTAGCCGGACAGAGTCTATTGCTGGGAGGATTTAAACAAGGTAAACAAATCCACTCGCAAA
ACAAAATCCCTTTATTGGGCGATATTCCTGTCGTAGGCCATTTGTTTCGCAATGATACGACTCAAGTACATAGTGTAATC
AGGCTGTTTTTGATTAAAGCCTCAGTAGTAAATAATGGCATATCTCATGGTTAA

Protein sequence :
MVVNKRLILILLFILNTAKSDELSWKGNDFTLYARQMPLAEVLHLLSENYDTAITISPLITATFSGKIPPGPPVDILNNL
AAQYDLLTWFDGSMLYVYPASLLKHQVITFNILSTGRFIHYLRSQNILSSPGCEVKEITGTKAVEVSGVPSCLTRISQLA
SVLDNALIKRKDSAVSVSIYTLKYATAMDTQYQYRDQSVVVPGVVSVLREMSKTSVPASSTTNGSPATQALPMFAADPRQ
NAVIVRDYAANMAGYRKLITELDQRQQMIEISVKIIDVNAGDINQLGIDWGTAVSLGGKKIAFNTGLNDGGASGFSTVIS
DTSNFMVRLNALEKSSQAYVLSQPSVVTLNNIQAVLDKNITFYTKLQGEKVAKLESITTGSLLRVTPRLLNDNGTQKIML
NLNIQDGQQSDTQSETDPLPEVQNSEIASQATLLAGQSLLLGGFKQGKQIHSQNKIPLLGDIPVVGHLFRNDTTQVHSVI
RLFLIKASVVNNGISHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssaC YP_216402.1 secretion system apparatus protein SsaC Virulence SPI-2 Protein 0.0 99
ssaC NP_460359.1 outer membrane secretin precursor Virulence SPI-2 Protein 0.0 99
spiA NP_456134.1 putative outer membrane secretory protein Virulence SPI-2 Protein 0.0 99
spiA NP_805065.1 outer membrane secretory protein Virulence SPI-2 Protein 0.0 99
spiA AAC44301.1 SpiA Virulence SPI-2 Protein 0.0 99
YPO0257 YP_002345337.1 type III secretion protein Virulence Not named Protein 6e-125 53
escC AAK26708.1 EscC Virulence LEE Protein 2e-96 45
escC AAL57535.1 EscC Virulence LEE Protein 2e-96 45
escC CAC81855.1 EscC protein Virulence LEE II Protein 2e-96 45
escC CAI43881.1 EscC protein Virulence LEE Protein 2e-96 45
escC YP_003223482.1 T3SS structure protein EscC Virulence LEE Protein 3e-96 45
escC YP_003232146.1 T3SS structure protein EscC Virulence LEE Protein 3e-96 45
escC AFO66299.1 putative type III complex subunit Virulence SESS LEE Protein 2e-100 44
escC AFO66408.1 putative type III complex subunit Virulence SESS LEE Protein 2e-100 44
unnamed AAL06362.1 EscC Virulence LEE Protein 2e-95 44
escC YP_003236095.1 T3SS structure protein EscC Virulence LEE Protein 6e-95 44
escC NP_290275.1 hypothetical protein Virulence LEE Protein 3e-95 44
escC AAC38377.1 EscC Virulence LEE Protein 2e-94 44
ECs4575 NP_312602.1 EscC Virulence LEE Protein 3e-95 44
escC AAC31520.1 L0041 Virulence LEE Protein 3e-95 44
escC ACU09465.1 type III secretion outer membrane pore YscC/HrcC family Virulence LEE Protein 3e-95 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spiA YP_150710.1 outer membrane secretory protein VFG0495 Protein 0.0 99
spiA YP_150710.1 outer membrane secretory protein VFG0819 Protein 1e-95 44
spiA YP_150710.1 outer membrane secretory protein VFG0723 Protein 1e-94 44