Gene Information

Name : GK0589 (GK0589)
Accession : YP_146442.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Resistance
Product : arsenate reductase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0394
EC number : -
Position : 614664 - 615086 bp
Length : 423 bp
Strand : +
Note : catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates

DNA sequence : 
ATGAAAAACAAAAAGATCATTTACTTCTTATGCACAGGTAACTCTTGCCGCAGCCAAATGGCAGAAGGATGGGCAAAAAA
ATATCTTGGCGACGAGTGGGAAGTGTACAGCGCCGGTATTGAAGCGCATGGACTAAATCCAAACGCGGTAAAAGTCATGA
AAGAAGTAGGAATTGATATTTCGAACCAGACATCGGATATCATTGATCCGGAAATTTTAAATAAAGCGGATTTGGTAGTA
ACATTATGTGGTCATGCAGCGGACCATTGTCCAGTAACCCCACCAAATGTGAAACGTGTTCATTGGGGATTTGATGATCC
GGCAAAGGCGGAAGGAACGGAGGAGGAAAAATTAGCTGTATTCCGTCGTGTTCGCGATGAAATCGGCGCGCGCATCAAAA
AATTTGCTGAAACAGGCGAATAA

Protein sequence : 
MKNKKIIYFLCTGNSCRSQMAEGWAKKYLGDEWEVYSAGIEAHGLNPNAVKVMKEVGIDISNQTSDIIDPEILNKADLVV
TLCGHAADHCPVTPPNVKRVHWGFDDPAKAEGTEEEKLAVFRRVRDEIGARIKKFAETGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsC YP_252023.1 arsenate reductase Not tested SCCmec Protein 2e-39 66
arsC YP_005754064.1 arsenate reductase Not tested Type-XI SCCmec Protein 8e-39 65
arsC YP_252016.1 arsenate reductase Not tested SCCmec Protein 9e-41 65

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GK0589 YP_146442.1 arsenate reductase BAC0581 Protein 9e-53 85
GK0589 YP_146442.1 arsenate reductase BAC0032 Protein 5e-39 65
GK0589 YP_146442.1 arsenate reductase BAC0580 Protein 4e-38 62