Gene Information

Name : GK0370 (GK0370)
Accession : YP_146223.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 412274 - 413962 bp
Length : 1689 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGGAAAACATCCGCTCGTTTATGTCGTTTCCGGAAAGCCGCAAAGTGTACATCGAAGGGTCGCGCCCGGATGTGCGCGT
GCCGATGAGAGAAATTGCTTTATCGCCAACGAAAACGCCGCAAGGAATGGTGGAAAACAAACCGGTGCGTGTCTACGATA
CGACGGGCCCGTATACGGATCCCGATTTTGAACCGGACGTGGAGAAAGGCTTGCCTCCTCTTCGCCGCCGCTGGATTGTC
GAGCGCGGCGATGTGGAGGAAATGGAGCGGTCTTCTGTTGCGATCCAACGTTCGCTTCCGTTTGTGCGCCGTCCATTGAG
GGCAAAGCCCGGAAAAACAGTGACACAAATGCATTACGCCAAACGGGGGATCATTACGCCAGAAATGGAGTTTGTCGCGA
TTCGTGAACAAATCGATCCAGAAATTGTCCGCCAAGAAGTCGCCGCTGGTCGGGCCATTATTCCGGCCAATATTAACCAT
CCAGAGAGCGAACCGATGATCATCGGACGTCGTTTCCATGTGAAAATTAATGCCAATATCGGCAACTCGGCTGTTTCTTC
ATCGATTGAAGACGAAGTGGAAAAATTGCTTTGGGCAGTGCGTTGGGGCGCCGATACGGTCATGGATTTATCGACCGGCA
AACACATTCATGAAACGCGCGAGTACATCATCCGCAATTCGCCGGTCCCCGTGGGAACGGTGCCGATTTATCAGGCGCTC
GAAAAGGTAGGAGGGGTGCCGGAGAAGCTGACATGGGACGTGTACCGCGAGACGCTCATCGAGCAGGCTGAACAAGGAGT
CGACTACATGACGATCCACGCCGGTGTGCGGCTTCATTACATTCCGCTCACCGCCAACCGGACGACCGGAATTGTCTCGC
GCGGCGGCTCGATCATCGCCCAATGGTGTTTGGCCCACCATGAAGAAAACTTTTTGTATACGCATTTTGAAGAAATCTGC
GAGATTTTGAAACAATACGATGTCGCGATCTCCCTTGGCGACGGCTTGCGCCCCGGCTCCATCGCCGATGCGAACGATGA
GGCGCAGTTTGCGGAACTCAAGACGCTCGGCGAGCTGACGAAAATCGCCTGGAAGCATGATGTGCAGGTGATGATCGAAG
GGCCGGGGCACATTCCGATGCATAAAATTCGCGAAAATGTCGAGCGGGAACAGGAAATTTGTCATGGAGCGCCGTTTTAT
ACGTTAGGGCCGCTTGTCACCGACATCGCGCCCGGGTATGACCATATTACGTCAGCGATTGGCGCCGCCATCATTGGCGC
TTATGGAACGGCGATGCTTTGTTACGTAACGCCCAAAGAACATTTAGGGTTGCCGAATAAAGAGGACGTACGCGCCGGGG
TCGTGGCCTATAAAATCGCCGCCCATGCGGCTGATCTGGCAAAAGGGCATCCAGCCGCTCAGCAGCGTGACGACGCGCTC
TCGAAAGCGCGCTTTGAATTTCGTTGGAACGATCAGTTCAATTTATCCCTCGATCCGGAACGGGCCCGCGAATACCATGA
TGAAACATTGCCGGCTGAGGCGGCGAAAACGGCTCATTTTTGTTCGATGTGCGGGCCGAAATTTTGTTCCATGAACATTT
CACATGAACTGCAACGGAAAATCAAAGAGGAGGGGATGAAAGAAAAAGCGCAACAATTTATTCGGCAAGGGTCGTCGCTG
TATCAATGA

Protein sequence :
MENIRSFMSFPESRKVYIEGSRPDVRVPMREIALSPTKTPQGMVENKPVRVYDTTGPYTDPDFEPDVEKGLPPLRRRWIV
ERGDVEEMERSSVAIQRSLPFVRRPLRAKPGKTVTQMHYAKRGIITPEMEFVAIREQIDPEIVRQEVAAGRAIIPANINH
PESEPMIIGRRFHVKINANIGNSAVSSSIEDEVEKLLWAVRWGADTVMDLSTGKHIHETREYIIRNSPVPVGTVPIYQAL
EKVGGVPEKLTWDVYRETLIEQAEQGVDYMTIHAGVRLHYIPLTANRTTGIVSRGGSIIAQWCLAHHEENFLYTHFEEIC
EILKQYDVAISLGDGLRPGSIADANDEAQFAELKTLGELTKIAWKHDVQVMIEGPGHIPMHKIRENVEREQEICHGAPFY
TLGPLVTDIAPGYDHITSAIGAAIIGAYGTAMLCYVTPKEHLGLPNKEDVRAGVVAYKIAAHAADLAKGHPAAQQRDDAL
SKARFEFRWNDQFNLSLDPERAREYHDETLPAEAAKTAHFCSMCGPKFCSMNISHELQRKIKEEGMKEKAQQFIRQGSSL
YQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 67
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 67
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 66