Gene Information

Name : GK3222 (GK3222)
Accession : YP_149075.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Resistance
Product : arsenate reductase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0394
EC number : -
Position : 3259148 - 3259567 bp
Length : 420 bp
Strand : -
Note : catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates

DNA sequence : 
ATGAAGAAAAAAGTCATATACTTTTTATGCACCGGCAACTCGTGCCGCAGCCAAATGGCGGAAGGCTGGGCGAAACAACT
TCTTGGTGAGGAATGGGAAGTGCACAGCGCCGGCATTGAAGCGCATGGCCTCAATCCGAATGCGGTGAAAGTGATGAAGG
AAGTCGGCATCGACATTTCGAACCAAACGTCTGACGTCATCGACCCGGATCTCCTCAACCGCGCTGATTTGGTCGTGACG
CTGTGCGGCCATGCGGCCGACCATTGTCCGGTCACTCCGCCGCACGTGAAGCGCGTCCATTGGGGCTTTGACGACCCGGC
GAAAGCGGAAGGGACGGAAGAGGAGAAGCTGGCGGTGTTCCGCCGCGTCCGCGATGAAATTGGCGCGCGCATCCGCCGGT
TTGCCGAGACGGGTGAATAG

Protein sequence : 
MKKKVIYFLCTGNSCRSQMAEGWAKQLLGEEWEVHSAGIEAHGLNPNAVKVMKEVGIDISNQTSDVIDPDLLNRADLVVT
LCGHAADHCPVTPPHVKRVHWGFDDPAKAEGTEEEKLAVFRRVRDEIGARIRRFAETGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsC YP_252016.1 arsenate reductase Not tested SCCmec Protein 8e-41 65
arsC YP_005754064.1 arsenate reductase Not tested Type-XI SCCmec Protein 1e-38 63
arsC YP_252023.1 arsenate reductase Not tested SCCmec Protein 1e-38 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GK3222 YP_149075.1 arsenate reductase BAC0581 Protein 1e-51 82
GK3222 YP_149075.1 arsenate reductase BAC0032 Protein 6e-39 64
GK3222 YP_149075.1 arsenate reductase BAC0580 Protein 1e-37 62
GK3222 YP_149075.1 arsenate reductase BAC0586 Protein 1e-14 41