Gene Information

Name : GK3198 (GK3198)
Accession : YP_149051.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3232264 - 3233784 bp
Length : 1521 bp
Strand : +
Note : -

DNA sequence :
ATGATCTACGCACAACCAGGCCAGCCAGGCGCGCTTGTCACATTTAAAAAGCGCTACGAAAACTTCATTGGCGGCAAATG
GGTGCCGCCGGTCGACGGCGAGTATTTCGAAAATATCACGCCAATCACCGGACAGCCGTATTGCGAAGTGCCGCGCTCAA
AAGCGGCGGACATCGAACTGGCGCTTGACGCCGCCCATGCGGCAAAAGACGCATGGGGACGCACGTCTCCAGCGGAGCGC
GCCCGTTTGTTGAACAAAATCGCCGACCGGATGGAAGAAAACTTGGAAATGCTCGCCGTTGCGGAAACATGGGAAAACGG
CAAGCCGATCCGCGAAACGTTGGCGGCTGACATCCCGCTTGCCATCGACCATTTCCGCTACTTCGCCAGCTGCATTCGCG
CGCAAGAAGGCACGATTTCGGAAATCGATCACGACACGGTCGCCTATCATTTCAAAGAACCGCTCGGCGTCGTCGGGCAA
ATCATCCCGTGGAACTTCCCGATTTTAATGGCGGCCTGGAAACTCGCTCCAGCGCTCGCGGCCGGCAACTGCGTCGTCTT
GAAACCGGCGGAGCAAACGCCGACGTCGATCCTCGTTCTCATCGAACTCATCGAGGATTTGCTTCCACCTGGCGTCGTCA
ACATCGTCAACGGCTTTGGCTTAGAAGCCGGCAAGCCGCTCGCCTCGAACCCGCGCGTGGCGAAAGTGGCGTTCACCGGT
GAAACGACGACCGGACGGCTCATCATGCAGTACGCCTCGCAAAACATCGTGCCGGTTACGCTTGAGCTTGGCGGCAAGTC
CCCGAACATTTTCTTCGCTGATGTGATGGACAAAGACGACGAGTTTCTCGATAAAGCGCTCGAAGGCTTTACGATGTTCG
CCTTAAACCAAGGCGAAGTGTGCACATGCCCGTCGCGCGCCCTCATCCATGAGTCGATTTACGACGCCTTTATGGAACGG
GCGCTTGAGCGCGTCAAGCAAATCAAGCAAGGCAATCCGCTCGATACGGAAACGATGATCGGCGCCCAAGCCTCCTCCGA
ACAGCTCGAGAAAATTTTGTCATACATCGACATCGGCAAACAGGAAGGCGCTGAGCTCTTGATCGGCGGCGAGCGGAACA
TGCTCGAAGGAGAACTCGCCGGCGGATACTATGTCAAGCCGACGATTTTCAAAGGGCATAACAAAATGCGCATTTTCCAA
GAAGAAATTTTCGGCCCAGTGCTCGCGGTCACAACGTTTAAAGATCACGACGAAGCGCTTTCAATCGCCAATGAAACGCT
GTACGGCCTTGGCGCCGGCGTCTGGACGCGCGACATCAACACCGCGTACCGCTTCGGCCGCGGCATCCAAGCAGGCCGCG
TCTGGACGAACTGCTATCACGTCTATCCGGCCCACGCGGCGTTTGGCGGCTACAAAATGTCCGGCATCGGCCGCGAAACG
CACAAAATGATGCTCGACCATTACCAACAAACGAAAAACTTGCTCGTCAGCTATTCGCCGAAAAAACTTGGCTTGTTCTA
A

Protein sequence :
MIYAQPGQPGALVTFKKRYENFIGGKWVPPVDGEYFENITPITGQPYCEVPRSKAADIELALDAAHAAKDAWGRTSPAER
ARLLNKIADRMEENLEMLAVAETWENGKPIRETLAADIPLAIDHFRYFASCIRAQEGTISEIDHDTVAYHFKEPLGVVGQ
IIPWNFPILMAAWKLAPALAAGNCVVLKPAEQTPTSILVLIELIEDLLPPGVVNIVNGFGLEAGKPLASNPRVAKVAFTG
ETTTGRLIMQYASQNIVPVTLELGGKSPNIFFADVMDKDDEFLDKALEGFTMFALNQGEVCTCPSRALIHESIYDAFMER
ALERVKQIKQGNPLDTETMIGAQASSEQLEKILSYIDIGKQEGAELLIGGERNMLEGELAGGYYVKPTIFKGHNKMRIFQ
EEIFGPVLAVTTFKDHDEALSIANETLYGLGAGVWTRDINTAYRFGRGIQAGRVWTNCYHVYPAHAAFGGYKMSGIGRET
HKMMLDHYQQTKNLLVSYSPKKLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-139 66
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-147 65
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-147 65
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-147 65
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-146 65
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-62 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GK3198 YP_149051.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 3e-139 66