Gene Information

Name : GK3096 (GK3096)
Accession : YP_148949.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 3118950 - 3120590 bp
Length : 1641 bp
Strand : -
Note : -

DNA sequence : 
ATGAAAACATATCGAATGACCGTCCAAGGCATGACATGCACCGGCTGTGAACAACATGTCGCCAGAGCGCTGGAGGCGAT
TGGGGCTAAGCTGATGGATGTCAGCTTCCGGCGCGGTGAAGTGGTATTCGCGCTGCCTGAGGGCACGGACGTTGACATGG
CGAGACAAGCGGTCAAAAACGCCCATTACGAGCCGGGGGAAGCCGAGGAGATCACCGCATCAGCCAGATCTGTTATCGAT
GGCGAGGGAGAGTATGATTACATGATCATCGGTTCCGGCGGGGCGGCGTTTTCCTCGGCGATCGAAGCGGTGAAATACGG
GGCGAAAGTGGCGATGGTCGAGCGCGGAACGGTCGGGGGGACGTGCGTCAATATCGGATGCGTGCCATCGAAGACGCTGC
TTCGGGCCGGAGAAATCTATGCGTTGGCGCGAAATCATCCGTTTCTCGGCCTGCATACATCCGCTGGTCCGGTTGATTTG
GCGCCGTTAGTGAAGCAAAAAAATGAACTGGTCGAGCAGCTTCGCCAAGCGAAATATGCAGACTTGATCGGAGAGTATGG
GTTCGATTTCATCCAAGGGGAGGCTCGGTTTATCGATCGCCAAACGATTGAAGTGAACGGCCAAACGCTGTCGGCGAAAC
GGTTTTTGATCGCGACAGGCGCTTCCCCGGCCGTGCCGGATATTCCGGGACTTCATGATGTCGACTACTTGACCAGCACG
ACCTTGCTTGAACTGAAAAAAGTGCCGAAGCGGCTCGCCGTCATCGGCGCCGGCTACATCGGGATGGAGTTGGGACAGCT
GTTCCACCATCTCGGCTCGGAGGTGACGTTGATGCAGCGAAGCTCGCGCCTGCTGAAAGAGTATGACCCGGAAATTTCCG
AAGCGGTGGCGCGGGCGCTCACAGAACAAGGCATCCGCGTCATCACCGGTGCTTCATTTGAACGGGTCGAACAAGACGGG
AATACGAAAAAAGTGTATGTGAACGTGGACGGACGCACCCGGGTCATCGAAGCGGACGAATTGCTCGTGGCTGCCGGGAG
AACGCCGAATACGGCGGCGTTGAACTTGCCGGCAGCCGGTGTGGAAGTCGGGGCGCGCGGGGAAATTTTGATCGACGAAT
ACACACGGACGACGAACCCGTCGATTTATGCGGCAGGCGATGTCACGCTCGGCCCGCAGTTCGTCTATGTCGCGGCCTAT
CAGGGAGCCGTTGCCGCGGCTAATGCCATAGGCGGGCTGAACAAGCGCTGGGATACGGCCGTCGTTCCGGCGGTGACGTT
CACCCATCCGGCCATCGCCACCGTCGGTTTGACCGAACAGCGGGCGAAAGAAAACGGGTATGACGTGAAAACGTCCGTCC
TGCCGCTTGAGGCGGTGCCGCGCGCCATCGTCAACCGGGAAACGACGGGGGTGTTTAAACTTGTCGCTGAGGCCCGTACG
GGCAAGCTGCTAGGCGCCCACATCGTCGCGGACAATGCCGGCGAGGTCATTTACGCCGCAGCGTTGGCGATTCAATTCGG
ATTAACGATCGACGACCTTCGCCACACGCTTGTCCCGTATTTAACGATGGCGGAGGGGCTGAAGCTGGCGGCGCTTACGT
TTGACCAAGATGTTTCGAAGTTATCGTGCTGCGCGGGATGA

Protein sequence : 
MKTYRMTVQGMTCTGCEQHVARALEAIGAKLMDVSFRRGEVVFALPEGTDVDMARQAVKNAHYEPGEAEEITASARSVID
GEGEYDYMIIGSGGAAFSSAIEAVKYGAKVAMVERGTVGGTCVNIGCVPSKTLLRAGEIYALARNHPFLGLHTSAGPVDL
APLVKQKNELVEQLRQAKYADLIGEYGFDFIQGEARFIDRQTIEVNGQTLSAKRFLIATGASPAVPDIPGLHDVDYLTST
TLLELKKVPKRLAVIGAGYIGMELGQLFHHLGSEVTLMQRSSRLLKEYDPEISEAVARALTEQGIRVITGASFERVEQDG
NTKKVYVNVDGRTRVIEADELLVAAGRTPNTAALNLPAAGVEVGARGEILIDEYTRTTNPSIYAAGDVTLGPQFVYVAAY
QGAVAAANAIGGLNKRWDTAVVPAVTFTHPAIATVGLTEQRAKENGYDVKTSVLPLEAVPRAIVNRETTGVFKLVAEART
GKLLGAHIVADNAGEVIYAAALAIQFGLTIDDLRHTLVPYLTMAEGLKLAALTFDQDVSKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-179 66
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-179 66
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 3e-84 45
merA ABQ57371.1 MerA Not tested SGI1 Protein 1e-84 44
merA AGK07021.1 MerA Not tested SGI1 Protein 1e-84 44
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 3e-83 44
merA AGK07079.1 MerA Not tested SGI1 Protein 1e-84 44
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-80 43
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-81 43
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-81 43
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 2e-81 43
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 1e-83 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GK3096 YP_148949.1 mercuric reductase BAC0224 Protein 0.0 70
GK3096 YP_148949.1 mercuric reductase BAC0651 Protein 2e-179 66
GK3096 YP_148949.1 mercuric reductase BAC0652 Protein 4e-82 42
GK3096 YP_148949.1 mercuric reductase BAC0650 Protein 2e-77 42
GK3096 YP_148949.1 mercuric reductase BAC0653 Protein 9e-81 41