Gene Information

Name : leuS (GK2842)
Accession : YP_148695.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2867413 - 2869830 bp
Length : 2418 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTTCAACCACCGCGAAATTGAACAAAAATGGCAGGACTATTGGGAGAAAAACAAAACGTTCCGCACGCCCGATGA
TGATGACAAGCCGAAGTTTTACGTTCTCGACATGTTCCCGTATCCATCCGGCGCCGGCTTGCACGTCGGCCATCCAGAAG
GATATACGGCGACCGATATTTTGGCGCGCATGAAGCGGATGCAAGGGTACAACGTCCTTCACCCGATGGGCTGGGACGCG
TTCGGGCTGCCGGCCGAGCAATATGCGCTCGATACCGGCAACGACCCGGCGGAGTTTACGCAAAAAAACATCGACAATTT
CCGCCGGCAAATCAAATCGCTTGGCTTTTCGTACGACTGGGACCGGGAGATCAATACGACCGACCCGAACTATTACAAAT
GGACGCAATGGATTTTCTTGAAGCTGTATGAAAAAGGGCTCGCCTACATGGATGAAGTGCCGGTCAACTGGTGTCCGGCG
CTCGGCACGGTGCTGGCGAACGAAGAGGTGATCAACGGCCGGAGCGAGCGCGGCGGGCATCCGGTCATCCGCAAGCCGAT
GCGGCAATGGATGCTGAAAATCACCGCCTATGCCGACCGCTTGCTTGAAGATTTGGAAGAGCTCGACTGGCCGGAAAGCA
TTAAAGAGATGCAGCGCAACTGGATTGGCCGTTCGGAAGGAGCGGAAATCGAGTTTGCCGTCCACGGCCATGACGAAACA
TTCACCGTGTTCACGACGCGTCCGGATACGCTGTTTGGCGCGACGTACACCGTCTTGGCGCCGGAGCATCCGCTCGTTGA
AAAAATCACGACGCCGGAGCAAAAGCCAGCCGTTGACGCCTACTTAAAGGAAATTCAAAGCAAAAGCGACCTTGAGCGCA
CCGATTTGGCGAAAGAAAAAACGGGCGTGTTCACCGGCGCGTACGCCATTCACCCGGTCACCGGCGATCGGCTTCCGATT
TGGATCGCTGACTACGTCTTGATGAGCTACGGCACCGGAGCGATCATGGCCGTGCCGGCGCACGATGAGCGCGACTACGA
GTTTGCGAAAAAATTCCACTTGCCGATGAAAGAAGTCGTCGCCGGCGGCGATATCGAAAAAGAACCGTACACCGGAGATG
GCGAGCATATCAACTCCGAGTTTTTGAACGGGTTGAACAAGCAGGAAGCGATCGACAAAATGATCGCCTGGCTTGAGGAG
CACGGCAAAGGGCGGAAAAAAGTGTCGTACCGGCTGCGCGACTGGCTGTTCAGCCGCCAGCGCTACTGGGGCGAGCCGAT
TCCGATCATCCATTGGGAAGACGGCACGATGACGCCGGTGCCGGAAGAGGAATTGCCGCTTGTGTTGCCGAAAACGGATG
AAATCCGTCCGTCGGGAACGGGCGAGTCGCCGCTGGCCAACATCGAAGAATGGGTCAATGTTGTCGACCCGAAAACCGGG
AAAAAAGGGCGGCGCGAAACGAACACGATGCCGCAATGGGCTGGAAGCTGCTGGTATTATTTACGCTACATCGACCCGCA
CAACGACAAGCAGCTCGCCGATCCGGAAAAGCTGAAAAAGTGGCTGCCGGTCGATGTTTACATCGGCGGGGCGGAGCACG
CGGTTTTGCATTTGCTTTATGCCCGCTTCTGGCATAAGTTTCTCTATGACCTTGGCATCGTGCCGACGAAAGAACCGTTC
CAAAAGCTGTTCAACCAAGGGATGATTTTAGGCGAAAACAACGAAAAAATGAGCAAATCAAAAGGCAATGTCGTCAACCC
GGACGACATCATCGAAAGCCATGGGGCCGACACCTTGCGGCTGTATGAAATGTTCATGGGGCCGCTTGAGGCGTCGATCG
CTTGGTCGACGAAAGGGCTTGACGGGGCGCGGCGCTTCCTCGACCGCGTCTGGAGGCTCTTTGTCACCGAGAATGGCGAA
CTGAACCCGAACATTGTCGACGAACCGGCAAACGATACGCTCGAGCGCATCTATCACCAAACGGTGAAAAAAGTGACGGA
AGACTACGAATCCTTGCGCTTTAACACCGCCATTTCGCAGCTTATGGTGTTCATCAACGAAGCGTACAAAGCGGAGCAAA
TGAAAAAAGAATACATGGAAGGCTTCGTCAAGCTCTTGTCGCCGGTCTGCCCGCACATCGGCGAGGAGCTGTGGCAAAAG
CTTGGCCACACGGACACGATCGCCTATGAACCGTGGCCGACGTATGATGAAACGAAGCTTGTGGAAGACGTCGTGGAAAT
CGTCGTGCAAATCAACGGCAAAGTGCGGTCGCGCTTGCACGTGCCAGTTGACTTGCCAAAAGAAGCGCTCGAGGAGCGGG
CGCTCGCCGATGAAAAAATCAAAGAGCAGCTTGAGGGCAAAACCGTGCGCAAAGTGATCGCCGTCCCCGGCAAGCTCGTC
AATATCGTCGCCAACTGA

Protein sequence :
MSFNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPA
LGTVLANEEVINGRSERGGHPVIRKPMRQWMLKITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGAEIEFAVHGHDET
FTVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKTGVFTGAYAIHPVTGDRLPI
WIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVAGGDIEKEPYTGDGEHINSEFLNGLNKQEAIDKMIAWLEE
HGKGRKKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLVLPKTDEIRPSGTGESPLANIEEWVNVVDPKTG
KKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDLGIVPTKEPF
QKLFNQGMILGENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVTENGE
LNPNIVDEPANDTLERIYHQTVKKVTEDYESLRFNTAISQLMVFINEAYKAEQMKKEYMEGFVKLLSPVCPHIGEELWQK
LGHTDTIAYEPWPTYDETKLVEDVVEIVVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLV
NIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67