Gene Information

Name : GK2739 (GK2739)
Accession : YP_148592.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2761080 - 2762843 bp
Length : 1764 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAGCGGAAAACGAAAATCGTCTGTACGATCGGGCCGGCAAGCGAGAGCGTAGACAAGCTCGTGCAATTGATCGAAGC
GGGGATGAACGTGGCGCGCCTCAACTTTTCGCACGGAGATCATGAGGAACACGGGCGGCGCATCGCCAACATTCGCGAGG
CGGCGAGGCGGACGGGCCAAACGGTCGCCATTTTGCTCGATACGAAAGGCCCGGAAATCCGCACGCACAATATGGAGAAC
GGCGCCGTCGAACTGAAGGAAGGGGCAAAGCTCATCATTTCGATGAGCGAAGTGCTCGGCACGCCGGAAAAAATTTCTGT
CACCTATCCGGGGCTGATCGATGATGTGTCCGTTGGTTCGAAAATTTTGCTGGACGACGGGTTGATCGGCCTTGAAGTCA
ACGCGGTCGACAAGCAAGCTGGAGAAATTGCCACGACCGTCCTAAACACCGGTGTGCTCAAAAACAAAAAAGGGGTCAAT
GTCCCCGGCGTGCGTGTCAATTTGCCGGGCATCACCGAGAAGGACCGAGCCGATATTTTATTTGGCATCCGCCAAGGCAT
CGACTTCATCGCCGCCTCGTTTGTGCGCCGGGCGTCTGATGTGCTCGAAATCCGCGAGCTGCTCGAGGCGAATGACGCCT
TACATATCCAAATTATCGCGAAAATTGAAAATGAAGAAGGCGTCGCCAACATCGATGAAATTTTGGAAGCCGCCGATGGC
CTCATGGTGGCGCGCGGCGACCTTGGCGTTGAGATTCCGGCTGAGGAAGTGCCTCTCATTCAAAAAATGCTCATTAAAAA
GTGCAACATGCTTGGCAAGCCGGTCATCACGGCGACGCAAATGCTCGACTCGATGCAGCGCAATCCGCGGCCGACGCGGG
CTGAGGCGAGCGATGTCGCCAACGCCATTTTTGACGGCACCGACGCCGTCATGCTTTCCGGAGAAACCGCAGCCGGCCAG
TATCCGGTCGAAGCGGTAAGGACGATGCACCAAATCGCGCTCCGCACCGAGCAGGCGTTGGAGCATCGCGACATTTTGTC
CCAGCGCACGAAAGAGAGCCGAACGACGATCACCGATGCCATCGGCCAATCGGTCGCCCACACAGCGCTCAATTTGGATG
TCGCGGCGATCGTGACGCCGACGGTGAGCGGAAAAACGCCGCAGATGGTGGCGAAATACCGCCCGAAAGCCCCGATCATC
GCGGTGACATCAAACGAAGCGGTCTCGCGGCGGCTGGCGCTCATTTGGGGCGTGTATACGAAAGAAGCACCGCATGTCAA
TACAACCGATGAAATGCTCGATGTGGCGGTCGACGCGGCAGTGCGCTCCGGCTTGGTGAAGCACGGCGACTTGGTCGTCA
TCACGGCCGGCGTGCCGGTCGGCGAAACGGGATCGACGAACTTAATGAAAGTGCACGTCATCAGCGACTTGCTTGCCAAA
GGGCAAGGCATCGGCCGCAAGTCGGCATTCGGCAAGGCGGTCGTCGCCAAAACGGCGGAAGAGGCGTGCCGAAAAATGGT
AGAGGGCGGCATTTTAGTCACCATCAGCACCGATGCCGATATGATGCCGGCGATCGAAAAAGCGGCGGCGATCATCACCG
AGGAAGGCGGGTTGACGAGCCATGCGGCGGTCGTCGGCTTAAGCCTTGGCATTCCGGTCGTCGTCGGGGTGGAAAATGCC
ACAAGCTTGTTTAAAGATGGGCAAGAGATCACGGTCGATGGCGGCTTTGGCGCCGTCTACCGCGGCCATGCGAGCGTGTT
GTAA

Protein sequence :
MKRKTKIVCTIGPASESVDKLVQLIEAGMNVARLNFSHGDHEEHGRRIANIREAARRTGQTVAILLDTKGPEIRTHNMEN
GAVELKEGAKLIISMSEVLGTPEKISVTYPGLIDDVSVGSKILLDDGLIGLEVNAVDKQAGEIATTVLNTGVLKNKKGVN
VPGVRVNLPGITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEANDALHIQIIAKIENEEGVANIDEILEAADG
LMVARGDLGVEIPAEEVPLIQKMLIKKCNMLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQ
YPVEAVRTMHQIALRTEQALEHRDILSQRTKESRTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPII
AVTSNEAVSRRLALIWGVYTKEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPVGETGSTNLMKVHVISDLLAK
GQGIGRKSAFGKAVVAKTAEEACRKMVEGGILVTISTDADMMPAIEKAAAIITEEGGLTSHAAVVGLSLGIPVVVGVENA
TSLFKDGQEITVDGGFGAVYRGHASVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-107 53
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-107 53
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-107 53
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-107 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GK2739 YP_148592.1 pyruvate kinase VFG0479 Protein 5e-108 53