Gene Information

Name : polA (GK2730)
Accession : YP_148583.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2749550 - 2752186 bp
Length : 2637 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGAGATTGAAAAAAAAGCTTGTTTTAATCGACGGCAGCAGCGTGGCGTACCGCGCCTTTTTTGCCTTGCCGCTTTTGCA
TAACGACAAAGGCATCCATACGAACGCCGTCTACGGGTTTACGATGATGTTGAATAAAATTTTGGCGGAAGAAGAGCCAA
CTCATATGCTTGTCGCGTTTGACGCCGGGAAAACGACGTTCCGGCATGAAGCGTTTCAAGAGTATAAAGGTGGGCGCCAG
CAGACGCCACCGGAGCTGTCGGAGCAGTTTCCGCTGTTGCGCGAGCTGCTGAGGGCATATCGCATCCCCGCCTATGAACT
CGAGAACTACGAAGCGGACGATATTATCGGAACGCTTGCCGCCCGCGCTGAGCAGGAAGGGTTTGAGGTGAAAGTCATTT
CCGGCGACCGCGATCTGACCCAGCTCGCCTCCCCCCATGTGACGGTGGACATTACGAAAAAAGGGATTACCGATATCGAA
CCATACACGCCGGAGACGGTCCGCGAAAAATACGGCTTAACTCCGGAACAAATCGTTGATTTGAAAGGATTGATGGGCGA
CAAATCGGACAACATCCCCGGAGTGCCGGGCATCGGGGAAAAGACGGCGGTCAAGCTGCTCAGGCAATTCGGCACGGTCG
AAAATGTGCTTGCCTCCATTGACGAGATCAAAGGCGAAAAGTTGAAAGAAACGCTGCGCCAACACCGGGAGATGGCGCTG
TTAAGCAAAAAGCTCGCCGCCATTCGCCGCGACGCCCCGGTCGAGCTCTCGCTTGATGACATCGTCTATCAAGGGGAAGA
CCGGGAGAAAGTGGTCGCTTTATTTAAAGAGCTTGGGTTTCAATCGTTTTTAGAGAAAATGGAATCGCCGTCATCAGAAG
AGGAAAAACCGCTTGCCAAGATGGCATTTACGCTTGCTGACCGCGTGACGGAGGAGATGCTTGCCGACAAGGCGGCGCTT
GTCGTTGAAGTGGTCGAGGAAAATTATCATGATGCGCCGATCGTCGGCATCGCTGTGGTCAACGAACATGGACGGTTTTT
CCTGCGCCCGGAGACGGCGCTTGCCGATCCGCAGTTTGTCGCCTGGCTTGGTGATGAAACGAAGAAAAAAAGCATGTTTG
ACTCAAAGCGCGCGGCAGTCGCCTTGAAATGGAAAGGAATTGAGCTATGCGGCGTTTCCTTTGATTTATTGCTGGCCGCC
TATTTGCTTGATCCGGCGCAAGGTGTTGATGATGTAGCTGCCGCAGCCAAAATGAAGCAATACGAAGCGGTGCGCCCGGA
TGAAGCGGTGTATGGCAAAGGGGCGAAGCGGGCCGTGCCGGATGAGCCAGTGCTAGCCGAGCATCTCGTCCGCAAGGCGG
CGGCGATTTGGGAGCTCGAACGGCCGTTTTTGGATGAGCTGCGCCGCAACGAACAAGATCGGTTGCTCGTCGAGCTTGAG
CAGCCGTTGTCTTCGATTTTGGCGGAAATGGAATTTGCCGGAGTGAAAGTGGATACGAAGCGGCTCGAACAGATGGGCAA
AGAGCTCGCCGAGCAGCTCGGCACGGTCGAGCAGCGCATTTATGAGCTCGCCGGCCAAGAATTCAACATCAATTCACCGA
AACAGCTCGGCGTCATTTTATTTGAAAAACTGCAGCTGCCCGTCTTGAAAAAAACGAAAACCGGCTACTCCACTTCGGCG
GATGTGCTTGAAAAACTTGCGCCTTATCACGAGATCGTGGAAAACATTTTGCATTACCGCCAGCTTGGCAAGTTGCAGTC
GACGTATATTGAAGGATTGCTGAAAGTCGTGCGACCCGATACAAAGAAGGTGCATACGATTTTCAATCAGGCGTTGACGC
AAACCGGACGGCTCAGCTCGACGGAGCCGAACTTGCAAAACATTCCGATTCGGCTTGAGGAAGGACGGAAAATCCGCCAA
GCGTTCGTGCCGTCGGAGTCTGATTGGCTCATTTTCGCCGCCGACTACTCACAAATTGAGTTGCGCGTCCTCGCCCATAT
TGCGGAAGATGACAATTTAATGGAAGCGTTCCGCCGCGATTTGGATATCCATACGAAAACAGCGATGGACATTTTCCAAG
TGAGCGAGGACGAAGTGACGCCCAACATGCGCCGTCAGGCGAAGGCGGTCAACTTTGGGATCGTTTACGGGATCAGTGAT
TACGGCTTGGCGCAAAACTTAAATATTTCGCGCAAAGAGGCGGCTGAATTCATCGAGCGCTACTTCGAAAGCTTCCCTGG
CGTGAAGCGGTATATGGAAAACATTGTGCAAGAAGCAAAACAGAAAGGGTATGTGACGACGCTGCTGCATCGGCGCCGCT
ATTTGCCGGATATCACGAGCCGCAACTTCAACGTCCGCAGCTTTGCTGAACGGATGGCGATGAACACGCCGATTCAAGGG
AGCGCCGCTGACATTATTAAAAAGGCGATGATCGATCTGAACGCCAGACTGAAGGAAGAGCGGCTGCAAGCGCGCCTTTT
GCTGCAGGTGCATGACGAGCTCATTTTGGAGGCGCCGAAAGAAGAGATGGAGCGGCTGTGCCGGCTCGTTCCGGAAGTGA
TGGAGCAAGCGGTCACACTTCGCGTGCCGCTCAAAGTCGATTACCATTACGGCTCGACATGGTATGACGCGAAATAA

Protein sequence :
MRLKKKLVLIDGSSVAYRAFFALPLLHNDKGIHTNAVYGFTMMLNKILAEEEPTHMLVAFDAGKTTFRHEAFQEYKGGRQ
QTPPELSEQFPLLRELLRAYRIPAYELENYEADDIIGTLAARAEQEGFEVKVISGDRDLTQLASPHVTVDITKKGITDIE
PYTPETVREKYGLTPEQIVDLKGLMGDKSDNIPGVPGIGEKTAVKLLRQFGTVENVLASIDEIKGEKLKETLRQHREMAL
LSKKLAAIRRDAPVELSLDDIVYQGEDREKVVALFKELGFQSFLEKMESPSSEEEKPLAKMAFTLADRVTEEMLADKAAL
VVEVVEENYHDAPIVGIAVVNEHGRFFLRPETALADPQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFDLLLAA
YLLDPAQGVDDVAAAAKMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVRKAAAIWELERPFLDELRRNEQDRLLVELE
QPLSSILAEMEFAGVKVDTKRLEQMGKELAEQLGTVEQRIYELAGQEFNINSPKQLGVILFEKLQLPVLKKTKTGYSTSA
DVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLLKVVRPDTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQ
AFVPSESDWLIFAADYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVSEDEVTPNMRRQAKAVNFGIVYGISD
YGLAQNLNISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLHRRRYLPDITSRNFNVRSFAERMAMNTPIQG
SAADIIKKAMIDLNARLKEERLQARLLLQVHDELILEAPKEEMERLCRLVPEVMEQAVTLRVPLKVDYHYGSTWYDAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 51