Gene Information

Name : hemC (GK2645)
Accession : YP_148498.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2661523 - 2662452 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGGAACATTGTCGTTGGCTCGCGGCGCAGCAAGCTTGCCTTGACCCAGACGAAGTGGGTGATCAACGAATTGAAACA
GCTTGGGGCGCCGTTTACGTTTGAAGTGAAAGAAATCGTCACGAAAGGAGATCGGGTGCTTGATGTTACGCTCTCGAAAG
TCGGGGGCAAAGGGTTGTTTGTGAAAGAGATTGAGCATGAATTGCTCGCCGGCGGCATCGATATGGCGGTCCATAGCATG
AAAGATATGCCGGCTGTGCTGCCCGAAGGTTTAGTGATCGGTGCGGTTTCGCGCCGCGAAGATGCACGCGATGTGCTTGT
CAGCAAAGGAAACCGGATGCTCTCCGACTTGCCGCCTGGGTCGGTCATTGGCACGAGCAGCTTGCGCCGTTCAGCGCAGC
TGCTTGCCTATCGCCCGGATTTGACGATCAAATGGATTCGCGGCAATATTGACACAAGGTTGGCGAAGCTCGAAAGCGAA
GAGTACGATGCGATCGTGCTGGCGGCGGCGGGTCTTGCGCGCATGGGTTGGGGCGATGACGTCATCAGCGACTATCTTCC
TTTTGATGTCTGTGTTCCGGCGGTCGGCCAAGGGGCGCTGGCGGTCGAATGCCGGGAGGATGATGACGAATTGCGCCAAT
GGCTCAGCCGGTTAAACGACGAGCAAACCGAGCGGGCTGTTCGGGCGGAGCGCGCCTTTTTGCAGCAAATGGAAGGAGGC
TGTCAAGTGCCGATTGCCGGCTACGCGGAAGTGAAGGAGGGGACGGTGCGTCTTACCGCGCTTGTCGCCTCCCCGGATGG
CAAAGAAATGTATAAAGAAATCGTCACTGGCGCCGATCCGGAAGCGGTCGGCCGACAGGCGGCTGCCATCTTGAGCGAAC
AAGGGGCAAAAGCGCTGATCGAGCGGGTGAAAAAGGAGCTGGGCGACTGA

Protein sequence :
MRNIVVGSRRSKLALTQTKWVINELKQLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLFVKEIEHELLAGGIDMAVHSM
KDMPAVLPEGLVIGAVSRREDARDVLVSKGNRMLSDLPPGSVIGTSSLRRSAQLLAYRPDLTIKWIRGNIDTRLAKLESE
EYDAIVLAAAGLARMGWGDDVISDYLPFDVCVPAVGQGALAVECREDDDELRQWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEVKEGTVRLTALVASPDGKEMYKEIVTGADPEAVGRQAAAILSEQGAKALIERVKKELGD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-58 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-58 47