Gene Information

Name : GK2000 (GK2000)
Accession : YP_147853.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2044347 - 2045828 bp
Length : 1482 bp
Strand : -
Note : -

DNA sequence :
ATGAGGATCAAGCAACATTATCCACTGTTTATTAACGGCCAGTATGTCGAGAGCAGCAACGGAGAAGTGTTTGAAACGGT
CAATCCGGCGACAGAAGAAGTGATTGCGACCGTCGCCAAAGCGACGAAAGAAGATGTAGACCATGCCGTCGAGGCGGCGC
GCACGGCGTTTGAATCGGGGAAATGGCCAAAAATGACGGGGGCGAAGCGAGCTCGCCTGTTGAATCAAATTGCCAACTTG
ATGAGAGAGCGATTCGATGACTTGGTGTATGCGGAAGTGCTAAACAGCGGTAAAACGGTTGATGCGGCCAAAGGACAAAT
TATGCAAGCGATTGAGGATTTTGAATTTTATGCGGCCGCGGCAATTACGTTACAAGGCGATGTCAACCAAGTGCCAAATG
GCTTTTTCAACTACACGGTCAAAGAGCCAGTCGGTGTATGCGGTCAAATCATCCCGTGGAACTATCCGTTGATGATGGCG
GCTTGGAAGCTCGCCCCAGCATTGGCGGCCGGATGCACGGTCGTGTTAAAGCCGGCAAGCTATACGCCGATCACCGCTTA
TATGTTGGCGGAAATTTGCCAAGAGGCCGGGGTTCCGGACGGCGTCGTCAATGTCATTGCTGGAAGCGGTTCCGAAATCG
GCCCGTATATGACCGAACATCCTGGAATTGACAAAGTCGCCTTCACCGGGGAGACGGAAACGGGCAAGGATATTATGCGG
CGCGCTTCGGAGACGTTGAAGCGGGTGACGCTGGAGCTTGGCGGGAAATCACCGAACATCGTGTTTGATGATTGTGATAT
CGAAGCGGCGGTCAACGGTTCGCTTTATGGCATTTTTTACAACACGGGCCAGTCGTGCGAAGCGCGTTCGCGGCTGTTTG
TGCATGAAAACATTTATGATGAGTTTATGGAAAAGTTGATCGAAAAAGCTTCCCGCATCCGCGTCGGCAACCCATTTGAA
AAAGGGGTGCATATGGGCGCGGTCATTTCGCGAAGCCATCAGCAAGTGATCGACAGCTATGTCAAGCTGGCGGTTGAGGA
AGGAGGCGAAATTTTATACGGTGGGAAAATTCCGGAAGGTGAGGAATTCGCGAAAGGCTACTGGTACATGCCGACTATTA
TTGGCAATGTAAGAAACGACATGCGGGTGGCGCAGGAAGAAATTTTCGGTCCGGTTGTCGTCGTCATGAAGTTTCACGAT
GAAGAAGAGGTCATCGAGCTGGCGAACGACACGATTTTTGGATTAGGATCAGCCGTTTGGACGAAAGACCACGGAAAAGC
CCATCGCGTTGCCGCGTGCATCCGCGCTGGAATTGTCATGATCAACTCGCCGATTTCCGCTTTCCCAGGCACGCCGTTTG
GTGGATACAAGCAGTCGGGATTTGGCCGCGAGCTGGCTCTTGAGACGTTGAACTTGTATACCGAGACCAAAAGCGTTGTT
TCTTATATCGGCGCTAAACCGTTGAACCTATTTGGCATTTGA

Protein sequence :
MRIKQHYPLFINGQYVESSNGEVFETVNPATEEVIATVAKATKEDVDHAVEAARTAFESGKWPKMTGAKRARLLNQIANL
MRERFDDLVYAEVLNSGKTVDAAKGQIMQAIEDFEFYAAAAITLQGDVNQVPNGFFNYTVKEPVGVCGQIIPWNYPLMMA
AWKLAPALAAGCTVVLKPASYTPITAYMLAEICQEAGVPDGVVNVIAGSGSEIGPYMTEHPGIDKVAFTGETETGKDIMR
RASETLKRVTLELGGKSPNIVFDDCDIEAAVNGSLYGIFYNTGQSCEARSRLFVHENIYDEFMEKLIEKASRIRVGNPFE
KGVHMGAVISRSHQQVIDSYVKLAVEEGGEILYGGKIPEGEEFAKGYWYMPTIIGNVRNDMRVAQEEIFGPVVVVMKFHD
EEEVIELANDTIFGLGSAVWTKDHGKAHRVAACIRAGIVMINSPISAFPGTPFGGYKQSGFGRELALETLNLYTETKSVV
SYIGAKPLNLFGI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-75 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-78 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-78 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-78 41
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-77 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GK2000 YP_147853.1 aldehyde dehydrogenase VFG0082 Protein 4e-76 41