Gene Information

Name : serS (GK0013)
Accession : YP_145866.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 21813 - 23087 bp
Length : 1275 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGATGTGAAAATATTGCGCACCCAGTTTGAAGAAGTGAAAGAAAAACTAATGCAGCGCGGCGGGGATTTGACGAA
CATCGACCGCTTTGAACAATTGGACAAAGACCGCCGCCGCTTGATCGCGGAAGTCGAAGAGCTGAAAAGCAAGCGCAACG
ATGTGTCGCAGCAAATCGCTGTCCTAAAGCGCGAGAAAAAGGACGCCGAGCCGCTGATTGCCCAAATGCGCGAAGTCGGT
GACCGCATTAAACGGATGGATGAACAAATTCGCCAGCTTGAGGCGGAACTCGACGACTTGTTGTTGTCAATTCCAAACGT
GCCGCACGAATCAGTGCCGATCGGCCAATCAGAAGAGGACAATGTGGAAGTGCGGAGATGGGGAGAGCCGCGTTCGTTTT
CCTTTGAGCCGAAGCCGCATTGGGAAATCGCCGATCGGCTCGGTTTGCTCGACTTTGAGCGAGCCGCCAAAGTGGCGGGA
AGCCGATTTGTCTTTTATAAAGGGTTAGGAGCGCGGCTTGAGCGGGCGCTCATCAACTTTATGCTTGACATCCATCTCGA
TGAATTCGGTTACGAAGAAGTGTTGCCGCCATATTTAGTGAACCGGGCGAGCATGATCGGAACCGGACAGTTGCCGAAAT
TTGCCGAGGATGCGTTCCATTTGGACAGCGAAGATTATTTCCTCATTCCGACCGCTGAGGTGCCGGTGACGAACCTGCAC
CGCGACGAAATTTTGGCCGCAGATGATTTGCCGATTTACTATGCGGCCTACAGCGCCTGCTTCCGCGCGGAAGCCGGGTC
GGCCGGCCGCGACACGAGAGGGCTGATCCGTCAGCATCAGTTCAATAAAGTCGAGCTGGTAAAGTTCGTAAAGCCGGAGG
ACTCGTACGATGAATTGGAAAAGCTGACGCGCCAGGCAGAGACGATTTTGCAACGGCTCGGGCTTCCGTACCGCGTTGTC
GCCTTGTGCACCGGAGACCTTGGATTCTCGGCGGCGAAAACGTACGATATTGAAGTTTGGCTGCCAAGTTACGGAACGTA
CCGGGAAATTTCGTCGTGCAGCAACTTTGAGGCGTTTCAAGCGCGCCGTGCCAACATCCGCTTCCGTCGGGATCCAAAAG
CGAAACCGGAGTACGTGCATACATTAAACGGTTCGGGGCTAGCCATTGGGCGGACGGTCGCCGCCATTTTGGAAAACTAC
CAGCAAGAAGACGGCTCGGTCATCGTTCCGGAAGCGCTTCGTCCTTACATGGGGAATCGGGACGTCATTCGCTGA

Protein sequence :
MLDVKILRTQFEEVKEKLMQRGGDLTNIDRFEQLDKDRRRLIAEVEELKSKRNDVSQQIAVLKREKKDAEPLIAQMREVG
DRIKRMDEQIRQLEAELDDLLLSIPNVPHESVPIGQSEEDNVEVRRWGEPRSFSFEPKPHWEIADRLGLLDFERAAKVAG
SRFVFYKGLGARLERALINFMLDIHLDEFGYEEVLPPYLVNRASMIGTGQLPKFAEDAFHLDSEDYFLIPTAEVPVTNLH
RDEILAADDLPIYYAAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYDELEKLTRQAETILQRLGLPYRVV
ALCTGDLGFSAAKTYDIEVWLPSYGTYREISSCSNFEAFQARRANIRFRRDPKAKPEYVHTLNGSGLAIGRTVAAILENY
QQEDGSVIVPEALRPYMGNRDVIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-133 62