Gene Information

Name : GK1061 (GK1061)
Accession : YP_146914.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 1086587 - 1087999 bp
Length : 1413 bp
Strand : +
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGGTAGTTGGCGATTTTGCAATTGAAACAGAAACGCTCGTCGTTGGCGCCGGCCCTGGCGGCTATGTCGCCGCCATCCG
CGCCGCACAGCTCGGCCAAAAAGTGACGATTGTGGAAAAAGGAAATTTGGGCGGCGTCTGCTTAAACGTCGGTTGCATCC
CGTCCAAGGCGCTTATCTCGGCAAGCCATCGCTACGAGCAGGCGAAGCATTCCGAAGAGATGGGCATCAAGGCGGAAAAC
GTCACGGTTGATTTCTCGAAAGTGCAAGAATGGAAAGCGAGCATCGTCAAAAAATTGACGGGCGGCGTCGAAGGACTTCT
CAAAGGCAACAAAGTCGACATCGTCAAGGGGGAAGCGTACTTCGTCGACGCCAATACGGTGCGCGTGGTCAACGGCGATA
GCGCGCAGACGTATACGTTTAAAAACGCGATTCTGGCCACCGGTTCGCGTCCGATCGAGCTGCCGAACTTCAAGTTTTCC
GGCCGCATTCTCGACTCGACCGGTGCGCTCAACCTCGGGGAAATCCCGAAATCGCTCGTTGTCATCGGCGGCGGCTACAT
CGGCATCGAACTCGGTACGGCTTACGCCAATTTTGGTGCGAAAGTGACGATTCTTGAAGGGGCCGGTGAGATTTTATCCG
GCTTTGAAAAGCAAATGGTGTCCATCATTAAGCGCCGTCTGAAGAACAAAGGGGTCGAAGTTGTGACGAATGCGCTCGCA
AAAGGAGCCGAAGAGCGTGCAGACGGCGTGACGGTCACGTATGAGGCGAACGGCGAAACGAAAACGATCGACGCCGACTA
TGTGTTGGTGACGGTCGGCCGCCGACCGAATACAGATGAACTTGGTCTTGAACAAATCGGCATCAAAATGACGAACCGCG
GCTTGATTGAAGTGGACCAACAATGCCGGACAAGCGTGCCGAACATTTTCGCCATCGGCGACATCGTTCCAGGCCCGGCG
CTTGCTCATAAAGCGTCGTATGAAGGGAAAGTGGCGGCGGAAGCCATCGCCGGCCATCCGTCGGTAGTGGATTACATCGC
CATTCCGGCTGTGGTCTTCTCCGATCCGGAATGCGCCTCGGTCGGCTACTTTGAACAACAGGCGAAAGAGGAAGGCATCG
ACGTCATTACGGCGAAATTCCCGTTTGCCGCCAACGGCCGCGCTCTGTCACTCAACGATACGGACGGTTTCCTGAAGCTT
GTCGTCCGCAAAGAAGACGGCGTTGTGATTGGAGCGCAAATCATCGGCCCGAACGCCTCGGATATGATCGCCGAGCTTGG
GCTGGCCATTGAAGCCGGCATGACGGCGGAAGATATCGCGTTGACGATTCATGCCCACCCGACGCTTGGCGAAATCGCCA
TGGAAGCGGCGGAAGTGGCGCTTGGCACGCCGATTCATATCATTGCGAAGTAA

Protein sequence :
MVVGDFAIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALISASHRYEQAKHSEEMGIKAEN
VTVDFSKVQEWKASIVKKLTGGVEGLLKGNKVDIVKGEAYFVDANTVRVVNGDSAQTYTFKNAILATGSRPIELPNFKFS
GRILDSTGALNLGEIPKSLVVIGGGYIGIELGTAYANFGAKVTILEGAGEILSGFEKQMVSIIKRRLKNKGVEVVTNALA
KGAEERADGVTVTYEANGETKTIDADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIEVDQQCRTSVPNIFAIGDIVPGPA
LAHKASYEGKVAAEAIAGHPSVVDYIAIPAVVFSDPECASVGYFEQQAKEEGIDVITAKFPFAANGRALSLNDTDGFLKL
VVRKEDGVVIGAQIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAMEAAEVALGTPIHIIAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 3e-114 52