Gene Information

Name : GK0078 (GK0078)
Accession : YP_145931.1
Strain : Geobacillus kaustophilus HTA426
Genome accession: NC_006510
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 97189 - 99621 bp
Length : 2433 bp
Strand : +
Note : -

DNA sequence :
ATGATGTTTGGCAGATTTACGGAACGGGCGCAAAAAGTGCTGGCGCTGGCGCAGGAAGAAGCCATTCGCCTCGGCCATAA
CAATATCGGCACAGAACATATTTTGCTCGGCCTCATCCGCGAGGGCGAGGGGATCGCGGCTAAGGCGCTCATGGCGCTTG
GGCTCGGCCCAGATAAAATTCAAAAAGAAGTCGAATCGCTCATTGGCCGTGGCAGTGAAGTGTCGCATACGATCCACTAT
ACACCGCGGGCGAAAAAAGTAATTGAGCTGTCGATGGATGAAGCGCGGAAGCTCGGCCATTCATACGTCGGCACAGAACA
TATTTTGCTTGGGTTGATCCGCGAAGGCGAAGGGGTGGCCGCCCGCGTGCTGAACAACTTGGGAGTAAGCTTGAACAAAG
CGCGCCAGCAAGTGTTGCAGCTGCTTGGCAGCAATGAGTCGATGTCAGGCCATGGCGGCGGTGCTTCGCACGTGAGCACT
CCGACGCTTGACAGCCTCGCCCGCGATTTGACAGCGATTGCCCGCGAAGGGCGGCTGGACCCGGTCATCGGCCGCAGTAA
AGAAATTCAGCGCGTCATTGAAGTATTAAGCCGGCGGACGAAAAATAATCCTGTGTTGATCGGCGAGCCGGGCGTTGGGA
AAACGGCCATTGCTGAAGGGTTAGCCCAACAAATCGTCAATAACGAAGTGCCGGAAACGCTGCGCGACAAGCGGGTCATG
ACGCTCGATATGGGGACAGTCGTCGCCGGAACGAAATACCGTGGAGAATTTGAAGACCGACTGAAAAAAGTGATGGATGA
AATTCGTCAAGCGGGCAACATCATCTTGTTTATCGATGAGCTGCATACATTAATTGGCGCCGGTGGGGCGGAAGGAGCGA
TCGACGCGTCGAACATTTTGAAACCGGCGTTGGCGCGCGGGGAGCTTCAATGCATCGGCGCGACAACGCTCGATGAATAC
CGGAAATATATTGAAAAAGACGCCGCGCTTGAACGCCGCTTTCAGCCGATTTACGTTGATGAACCGACAGTGGAAGAATC
GATCCAAATTTTAAAAGGGTTGCGCGATCGGTATGAAGCGCACCACCGCGTTTCGATTTCCGACGAGGCGATCGTGCAAG
CCGTCAAGTTGTCCGACCGCTACATTACCGACCGTTTCTTGCCGGATAAGGCGATCGATTTGATCGACGAGGCTTGCTCG
AAAGTGCGCCTTCGTTCGTTCACCGCACCGCCGAAATTGAAAGAACTTGAACAAAAGCTCGAGGAAGTGCGGAAAGAAAA
AGACGCGGCCGTGCAAAGCCAAGAGTTTGAGAAAGCGGCGTCGCTGCGCGATATGGAACAGCGGCTGCGCGAAGAACTGG
AGGAAACGAAACGTGCGTGGAAAGAAAAACAAGGCCAAGAAAATTTGGAAGTGACGGTCGAAGACATCGCCGCGGTCGTC
TCGAGTTGGACCGGCATTCCGGTATCGAAGCTCGCTGAGACGGAAACGGAGCGGCTGCTCAAGCTGGAAGAAATTTTGCA
TTCGCGTGTCGTCGGCCAAGACGAGGCGGTCAAAGCGGTCGCCAAAGCGGTGCGCCGCGCCCGTGCTGGCCTGAAAGACC
CGAAACGCCCGATCGGTTCGTTCATTTTCCTTGGTCCGACCGGGGTTGGGAAAACGGAGTTGGCTCGAGCCTTGGCAGAA
GCGATGTTTGGCGATGAAGACGCCCTCATTCGCATCGATATGTCCGAGTATATGGAAAAACACTCAACATCGCGGCTCAT
CGGGTCGCCGCCGGGGTATGTCGGTTATGAAGAAGGCGGCCAGCTGACGGAAAAAGTGCGCCGCAAGCCGTATTCGGTTG
TCCTGTTAGATGAGATGGAAAAAGCGCATCCGGACGTGTTCAATATTTTGCTGCAAGTGTTGGAAGATGGGCGGCTGACT
GACTCGAAAGGGCGGACGGTCGACTTCCGCAACACGATCATCATCATGACGTCCAACGTCGGCGCCGATGCGCTGAAACG
GAATAAGTACGTTGGCTTCAACATTCAAGACGGGAACCAGCAATACAAAGATATGAAAAGCAAAGTGATGGATGAGCTGA
AAAAAGCATTCCGTCCAGAGTTTTTAAACCGGATCGACGAAATCATCGTCTTCCATTCGCTCGAAAAAGACCATCTGAAA
CAAATCGTCCGATTGATGGCCGATACGCTCGTGAAGCGGCTGAAAGAGCAAGACATTGATCTTGAGCTGACGGAGGCCGC
CATTGAGAAAATCGCCGCCGAAGGGTTCGATCCAGAATACGGTGCCCGCCCGCTGCGCCGCGCCTTGCAAAAGCATGTTG
AAGACCGTTTGTCCGAAGAATTGTTAAAAGGCACGATCGCCAAAGGGCAAAAAGTCGTCGTGGATGTCAAAGACGGGGAG
TTTGTCGTATTGTCGAAACAAGCGGTCGTGTGA

Protein sequence :
MMFGRFTERAQKVLALAQEEAIRLGHNNIGTEHILLGLIREGEGIAAKALMALGLGPDKIQKEVESLIGRGSEVSHTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESMSGHGGGASHVST
PTLDSLARDLTAIAREGRLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKYIEKDAALERRFQPIYVDEPTVEESIQILKGLRDRYEAHHRVSISDEAIVQAVKLSDRYITDRFLPDKAIDLIDEACS
KVRLRSFTAPPKLKELEQKLEEVRKEKDAAVQSQEFEKAASLRDMEQRLREELEETKRAWKEKQGQENLEVTVEDIAAVV
SSWTGIPVSKLAETETERLLKLEEILHSRVVGQDEAVKAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
AMFGDEDALIRIDMSEYMEKHSTSRLIGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEMEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTIIIMTSNVGADALKRNKYVGFNIQDGNQQYKDMKSKVMDELKKAFRPEFLNRIDEIIVFHSLEKDHLK
QIVRLMADTLVKRLKEQDIDLELTEAAIEKIAAEGFDPEYGARPLRRALQKHVEDRLSEELLKGTIAKGQKVVVDVKDGE
FVVLSKQAVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 59
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-88 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GK0078 YP_145931.1 ATP-dependent Clp protease ATPase VFG0079 Protein 0.0 79
GK0078 YP_145931.1 ATP-dependent Clp protease ATPase VFG0080 Protein 3e-141 53