Gene Information

Name : TTHA0875 (TTHA0875)
Accession : YP_144141.1
Strain : Thermus thermophilus HB8
Genome accession: NC_006461
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 833881 - 835146 bp
Length : 1266 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGGTGGACCTCAAGCGCCTGCGCCAGGAACCCGAGGTCTTCCACCGGGCCATCCGGGAAAAGGGGGTGGCGCTGGACCT
GGAAGCCCTCCTCGCCCTGGACCAGGAGGTCCAGGAGCTGAAAAAGCGCCTCCAGGAGGTCCAGACCGAGCGCAACCAGG
TAGCCAAGCGGGTCCCGAAGGCCCCCCCGGAGGAGAAGGAGGCCCTCATCGCCCGGGGCAGGGCCCTGGGGGAGGAGGCG
AAGCGGCTGGAGGAGGCCCTAAGGGAGAAGGAGGCGCAGCTTGAGGCCCTCCTCCTCCAGGTCCCCCTCCCCCCCTGGCC
CGGGGCGCCCGTGGGGGGGGAGGAGGCGAACCGGGAGATCAAGCGGGTGGGGAGCCCGCCGGAGTTTTCCTTCCCTCCTT
TGGACCACGTGGCCCTCATGGAGAAAAACGGCTGGTGGGAGCCCAGGATCAGCCAGGTCTCGGGAAGCCGCTCCTACGCC
CTCAAAGGGGACCTCGCCCTTTACGAGCTCGCCCTCCTCCGCTTCGCCATGGACTTCATGGCGCGGCGGGGCTTCCTCCC
CATGACCCTCCCCTCCTACGCCCGGGAGAAGGCCTTCCTCGGCACCGGCCACTTCCCCGCTTACCGCGACCAGGTCTGGG
CCATCGCCGAGACCGACCTCTACCTCACGGGCACCGCCGAGGTGGTCCTGAACGCCCTCCACTCCGGGGAGATCCTCCCC
TACGAGGCCCTTCCTTTGCGCTACGCCGGCTACGCCCCCGCCTTCCGCTCCGAGGCGGGAAGCTTCGGAAAGGACGTGCG
GGGGCTCATGCGGGTCCACCAGTTCCACAAGGTGGAGCAGTACGTCCTCACCGAGGCCAGCCTCGAGGCCTCCGACCGGG
CCTTCCAGGAACTCCTGGAAAACGCCGAGGAGATCCTGCGGCTTCTAGAGCTCCCCTACCGCCTGGTGGAGGTGGCCACA
GGGGACATGGGCCCGGGGAAGTGGCGGCAGGTGGACGTTGAGGTCTATCTGCCCTCGGAGGGGCGGTACCGGGAAACCCA
CTCCTGCTCGGCCCTTCTGGACTGGCAGGCCCGGCGGGCGAACCTCCGCTACCGCGACCCCGAAGGCCGGGTCCGGTACG
CCTACACCCTGAACAACACCGCCCTCGCCACCCCCCGCATCCTGGCCATGCTCCTGGAAAACCACCAGCTCCAAGACGGC
CGGGTGCGGGTGCCCAAGGCCCTCGTCCCCTACATGGGCAAGGAGGTGCTGGAGCCGTGCGGATAG

Protein sequence :
MVDLKRLRQEPEVFHRAIREKGVALDLEALLALDQEVQELKKRLQEVQTERNQVAKRVPKAPPEEKEALIARGRALGEEA
KRLEEALREKEAQLEALLLQVPLPPWPGAPVGGEEANREIKRVGSPPEFSFPPLDHVALMEKNGWWEPRISQVSGSRSYA
LKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHSGEILP
YEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVAT
GDMGPGKWRQVDVEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTALATPRILAMLLENHQLQDG
RVRVPKALVPYMGKEVLEPCG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-44 42