Gene Information

Name : TTHA0837 (TTHA0837)
Accession : YP_144103.1
Strain : Thermus thermophilus HB8
Genome accession: NC_006461
Putative virulence/resistance : Resistance
Product : metallo-beta-lactamase
Function : -
COG functional category : R : General function prediction only
COG ID : COG0491
EC number : -
Position : 802182 - 803618 bp
Length : 1437 bp
Strand : -
Note : similar to GB:AAS80833.1 percent identity 99 in 478 aa

DNA sequence :
ATGATCTTTCGCCAGATCCACGAGGAAGGCCTCGCGCAGATGAGCTACCTCCTGGGCTGCGCCGCCACCGGGGAGGCCCT
GGTGGTGGACCCCAGGCGGGACGTGGACGTGTACCTGGAGCTCGCCCAGTCCTTGGGCCTCCGCATCACCGCCATCGCCG
AGACCCACATCCACGCCGACTACCTCTCGGGGGCGAGGGAGCTCGCCCGGGCCACGGGGGCCACCCTGTACCTCTCCGAC
GAGGGGGACGAGAACTGGAAGTACAAGGGCCTCGAGGGCTTCCCCCACGTCCTCCTCAAGGACGGGGACGAGTTCAAGGT
GGGGAACATCCGCGTCCGGGCGGTCCACACCCCGGGCCACACCCCCGAGCACCTCTCCTTCCTGGTGGCGGACGGGGCGG
TGACGGACGAGCCCCTCCTCTTCCTCACGGGGGACTTCGTCTTCGTGGGGGACGTGGGCCGGCCGGACCTTTTGGAAGAG
GCGGCGGGGATCAAGGGCACGGCGGAGCCCGGGGCGAGGCGGATGTTTAGGAGCCTCAAGGAAAAGTTCCTCACCCTTCC
CGACCACGTCCAGGTCTGGCCCGGCCACGGGGCGGGCTCCGCCTGCGGCAAGGCGCTTGGGGCCCTCCCGGCCACCACCG
TGGGGTACGAACGCCGCCACGCCTGGTGGGCGGAGTACCTGGAGCGGGACGACGAGGAGGGGTTCGTGAAGGCCCTCCTC
CAGGGCCAGCCCGAGGCCCCCACCTACTTCAAGGAGATGAAGCGGCTGAACCGGGACGGGATGGCCATCCTGGGCGGCCT
TCCCCACCCGGGCCGCCTCACCCCGGCCCAGTTTGAGCGCTGGCTGAGGGAGGGGGCCATCCTCGTGGACACCCGGGACA
AGTTCGCCTTCGCCGGCGGGCACATCCCGGGGAGCATCAACATCCCCGCGGGGAAGAACTTCTCCACCTGGGCGGGCTGG
CTCCTCCCCTACGACCGCCCCCTCGTCCTCCTCGCCCGGCCCGAGGAGGTGGAGGCCCTCACCCGGGCCCTCGTCCGCAT
CGGCCTGGACGAGGTGGTGGGGTACATCCCGGGGCTGGAGGGCTACGCCCAGGGCGAGCTGGAAACCGTCCCCCAGGTCA
CCGCCAAGGAGGCCAAGGAGCTCTGGGAGAAGGGGAAGGCCTTCGTCCTGGACGTGCGCGGGCGGGACGAGTACCTCGCG
GGGCACATCCCCGGGGCCCAAAACATCCACGCGGGCCGCGTCCTCGCCCACCTGGACCGGCTCCCCAAGGACAGGCCCCT
CATCGTCCACTGCGTGGGCGGGGACCGCTCCAGCACCGCCATCAGCGCCCTACTGGCCCACGGTTTTAGAAACGCCCTGA
ACCTCACCGGGGGGATCAAGGCTTGGCGGGAGGCGGGCTTCCCCGTGGTGCAGGGCGAGGAACTGGTGCAGGCCTAA

Protein sequence :
MIFRQIHEEGLAQMSYLLGCAATGEALVVDPRRDVDVYLELAQSLGLRITAIAETHIHADYLSGARELARATGATLYLSD
EGDENWKYKGLEGFPHVLLKDGDEFKVGNIRVRAVHTPGHTPEHLSFLVADGAVTDEPLLFLTGDFVFVGDVGRPDLLEE
AAGIKGTAEPGARRMFRSLKEKFLTLPDHVQVWPGHGAGSACGKALGALPATTVGYERRHAWWAEYLERDDEEGFVKALL
QGQPEAPTYFKEMKRLNRDGMAILGGLPHPGRLTPAQFERWLREGAILVDTRDKFAFAGGHIPGSINIPAGKNFSTWAGW
LLPYDRPLVLLARPEEVEALTRALVRIGLDEVVGYIPGLEGYAQGELETVPQVTAKEAKELWEKGKAFVLDVRGRDEYLA
GHIPGAQNIHAGRVLAHLDRLPKDRPLIVHCVGGDRSSTAISALLAHGFRNALNLTGGIKAWREAGFPVVQGEELVQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB83478.1 - Not tested SCC 12263 Protein 3e-79 42
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 2e-78 41
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 1e-78 41