Gene Information

Name : TTHA0542 (TTHA0542)
Accession : YP_143808.1
Strain : Thermus thermophilus HB8
Genome accession: NC_006461
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 504982 - 507192 bp
Length : 2211 bp
Strand : -
Note : similar to GB:AAS80522.1 percent identity 100 in 736 aa

DNA sequence :
ATGAACCGATACGACGACCGCGCCAGGCTGGTCTTTCACTACGCAAGAGAGGAGGGGAGCCGCTTAGGCCACTCCATGAT
CGGCCCGGAGCACCTCCTCCTGGGCCTGATGCGCGAGGGGGGGACGGCGGCCCGCATCCTCCAGGAGTACGGCGCGAGCC
TCGAGGCCATGCGCCGCATGGTGGAGGAGCTGGTGGGCCGGGGGGAGGGCGGGCGCACCGGGGAGCCCCCCGCCATCACC
CCGAGGGCGAGGCGGGTCATGGAGCTCGCCAGCGCCGAGGCCCGCAACATGGGCTCCCCCGTCATCGGCACGGAGCACAT
CCTCCTCGGCATCATCCGGGAGGGGGACGGGATCGCCTACCGCATCCTCAGCCACTTCGCCAAGGACGTGGACGCCATCC
GCTGGAGGGTCCTGGCCATGGCCGAGGGCCGCGAGCGGGAAAAGCCTGTGAACACCCCCTTCCTGGACGAGTACGGCCGC
GACCTCACCAAGGAGGCCCGGGAAGGAAAGCTGGACCCGGTGATCGGCCGCCAGGAGGAGATCAACCGGGTGATCCAGAT
CCTCGCCCGGCGCACCAAGAACAATCCCGTGCTCATCGGCGACCCCGGGGTGGGCAAGACGGCCATCGTGGAGGGCCTGG
CCCAGGCCATCGTGGAGGGCCGGGTCCCCCCCATCCTCAAGGGGGCCCGGGTGGTGGCCATTGACCTCGCCGGGGTGGTG
GCGGGGACCAAGTACCGGGGCGAGTTTGAGGAGCGCCTGCGGCAGATCATTGAGGAGCTCAAGAACGCCAAGGTCATCGC
CTTCATTGACGAGCTCCACACCCTGATCGGGGCGGGCGGGGCCGAGGGCACCCTGGACGCCGCCAACATCCTCAAGCCCG
CCCTGGCCCGCGGGGAGATCCAGGTGATCGGGGCCACCACCACCGGGGAGTACCACCGCTACATAGAGAAGGACGCGGCC
CTGGAGCGGCGCTTCCAGCCGGTGATCGTCCTCGAGCCTTCCCCGGAGGAGACCCTGGAGATCCTCAAGGGCCTCCGCCC
CCGGTACGAGGCCCACCACGGGGTGATCATCCCCGACGAGATCCTGGAGCTTGCGGTGAAGATCGGGATCCGCTCGCTTC
CCGGGCGCAACTTCCCCGACAAGGCCATTGACCTCATTGACGAGGCGGCCTCGAGGGTGCGCCTGAACGCCTCCTTGGGC
CTCCCCGTGGCGGAGGAAGAGGACGGCACCCCCATCGTCACCCGGGAGGACGTGGAGGCGGTGGTGGACTCCTGGGGCGG
GGTCTACGTGGACGACAAGGACGACGAGAAGCTCATGCGCCTGGAGGAGGAGCTCAGGAAGCGGGTGGTGGGCCAGGAGG
AGGCCATCCGCGCCCTGGCGAACGCCCTCCGCCGGGCCCGGGTGGGGCTTGGGGGAAGGACCCGGGTGGCGGCGAGCTTC
CTCTTCGTGGGGCAAAGCGGCGTGGGCAAGACCCAGCTCGCCAAGGCCCTGGCCGAGGTCCTCTTCGGCTCGGAGAGGGC
CCTCATCCGCTTTGACATGTCCGAGTTCCAGGAGCCCCACTCCATCTCCAAGCTCATCGGGGCCCCGCCGGGCTATGTGG
GCTACGAGCAGGGGGGCCGCCTCACCGAGGCCGTGCGCCGCCAGCCCTTCAGCGTGGTCCTCCTGGACGAGATTGAGAAG
GCCCACCCCGACATCTACAACACCTTCCTCCAGGTGCTGGACGAGGGCCGCCTCACGGACGGCATGGGCCGCACCGTGGA
CTTCCGCCGGGTCATCCTCATCATGACCTCCAACACCGGCTACAACGTGGGCCCCGCCATCGGCTTCACCTCCAAGGAGG
TGGACACGGAGTCCCCCCTGAAGGCCCTCTTCACCCCCGAGTTTCTGGACCGGCTGGACGAGGTCATCCGCTTCCGGCCC
CTCACGGAGGAGGAGCTGGTGCGGGTGGCCGAGATGATGCTGGAGGACATCCGCAAGGAGCTCCAGGCCCGGGACGTCCA
GGTGAGCTTCGCCCCCGAATTGGCCCGCTTCCTGGTGGACCAGGCCCCCAAGACGGGGAGCGCCCGCGCCCTGCGGAGCG
TCCTAAGGGAGCGCATAGAGGACCCCTTGGCCGTCGCCCTCCTGCGGAAGCCCACGGGCCGGATCCACGTGAGCGTGGAG
GGAGGCCAGGTGGCCTTCCACGAGGTGGAGGGGGAGGAGCTCCTCGTCTAG

Protein sequence :
MNRYDDRARLVFHYAREEGSRLGHSMIGPEHLLLGLMREGGTAARILQEYGASLEAMRRMVEELVGRGEGGRTGEPPAIT
PRARRVMELASAEARNMGSPVIGTEHILLGIIREGDGIAYRILSHFAKDVDAIRWRVLAMAEGREREKPVNTPFLDEYGR
DLTKEAREGKLDPVIGRQEEINRVIQILARRTKNNPVLIGDPGVGKTAIVEGLAQAIVEGRVPPILKGARVVAIDLAGVV
AGTKYRGEFEERLRQIIEELKNAKVIAFIDELHTLIGAGGAEGTLDAANILKPALARGEIQVIGATTTGEYHRYIEKDAA
LERRFQPVIVLEPSPEETLEILKGLRPRYEAHHGVIIPDEILELAVKIGIRSLPGRNFPDKAIDLIDEAASRVRLNASLG
LPVAEEEDGTPIVTREDVEAVVDSWGGVYVDDKDDEKLMRLEEELRKRVVGQEEAIRALANALRRARVGLGGRTRVAASF
LFVGQSGVGKTQLAKALAEVLFGSERALIRFDMSEFQEPHSISKLIGAPPGYVGYEQGGRLTEAVRRQPFSVVLLDEIEK
AHPDIYNTFLQVLDEGRLTDGMGRTVDFRRVILIMTSNTGYNVGPAIGFTSKEVDTESPLKALFTPEFLDRLDEVIRFRP
LTEEELVRVAEMMLEDIRKELQARDVQVSFAPELARFLVDQAPKTGSARALRSVLRERIEDPLAVALLRKPTGRIHVSVE
GGQVAFHEVEGEELLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-128 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TTHA0542 YP_143808.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0080 Protein 5e-122 49
TTHA0542 YP_143808.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0079 Protein 6e-131 45