Gene Information

Name : TTHA0003 (TTHA0003)
Accession : YP_143269.1
Strain : Thermus thermophilus HB8
Genome accession: NC_006461
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2490 - 3914 bp
Length : 1425 bp
Strand : +
Note : similar to GB:AAS81953.1 percent identity 99 in 474 aa

DNA sequence : 
ATGCCGCCTTTTAAGCGCACCAAGATCGTGGCCACCCTGGGGCCGGCCACGGACGACAAGGAGGTGATCCGCGCCCTGGC
GGAGGCCGGGGCCGACGTCTTCCGCCTGAACTTCAGCCACGGCGCCCCCGAGGACCACAGGCGCCGGGTGGGCTGGGTGC
GGGAGGTGGCGGAGGAGCTCGGCCGAACCCTGGCCGTCCTCCAGGACCTCCAGGGCCCGAAGATCCGTGTGGGCCGTTTC
CGGGAGGGCCAGGTTCTCCTCCGCCCGGGGCAGAGGTTCGTCCTCACCGCCGAGCCCGTGGAGGGGGACGAGCACCGCGT
TTCCGTGAGCTACAAGGGGCTTCCCGAGGACGTTTCCCCGGGGCAGATCCTCCTTCTGGACGACGGCCGCATCCGGCTCA
AGGTCCTGGAGGTCCGGAGCCCGGAGATCCTCACGGAGGTGGAGGTGGGCGGGGTCCTCTCCAACAACAAGGGGATCAAC
ATCCCTGGGGCGGACCTCTCCATCCCCGCCCTCTCGGAGAAGGATATCCAGGACCTGGCCCTGGGGGCGGAGCTCGGGGT
GGACTGGGTGGCGGTCTCCTTCGTCCGCACGCGGGACGACCTCCTCCTCGCCCGGCACTACCTCTCCCGCTACGGCTCCA
AGGCCAGGCTCATGGCCAAGATCGAGAAGCCCTCGGCCGTGGCCCGGTTTGAGGAGATCCTGGAGGAGGCGGACGGGATC
ATGGTGGCCCGGGGGGACCTCGGGGTGGAGATGCCCCTGGAGGAGGTGCCCATCGTCCAGAAGCGCCTCATCCTCCGGTG
CATCGCCGCCGGGAAGCCGGTGATCACCGCCACCCAGATGCTGGAGTCCATGGTGCAGAACCCGAGCCCCACCCGGGCCG
AGGCCTCGGACGTGGCCAACGCCATCTTTGACGGGACCGACGCGGTGATGCTCTCCGCGGAGACGGCGGCCGGGGCCTAC
CCGGTGGAGGCGGTGGCCATGATGGCGAGGATCGCCAAGGCGGTGGAGTCTTCCCCGGAGTTCTTGCAGAAGCTCAACGT
CCTCCGCCCCGCCCCCACCCCCACCACCCAGGACGCCATCGCCCAGGCGGCGGACGACGTGGTGGAGGCGGTGGGGGCCC
GGGCCATCGTGGTCTTCACGGCCACGGGCGGCTCGGCGCGGAGGATCGCCCGCACCCGGCCCCAGGTGCCCATCCTGGCC
CTCACCCCGAACCCCGAGGTGCGGAACCAGCTGGCCTTGGTCTGGGGGGTCTACCCCCATCTCGCCCCCGACCCCCAGGA
CACCGACGACATGGTCCGCATCGCCCTCAGGGAGGTGAAGGCCCTGGGGCTCGCCCAGGTGGGGGACCGGGTGGTCATCG
CCGCCGGGGTTCCCTTCGGGGTCCGGGGGACGACGAACCTCATCCGCGTGGAGCGGGTGGGGTAG

Protein sequence : 
MPPFKRTKIVATLGPATDDKEVIRALAEAGADVFRLNFSHGAPEDHRRRVGWVREVAEELGRTLAVLQDLQGPKIRVGRF
REGQVLLRPGQRFVLTAEPVEGDEHRVSVSYKGLPEDVSPGQILLLDDGRIRLKVLEVRSPEILTEVEVGGVLSNNKGIN
IPGADLSIPALSEKDIQDLALGAELGVDWVAVSFVRTRDDLLLARHYLSRYGSKARLMAKIEKPSAVARFEEILEEADGI
MVARGDLGVEMPLEEVPIVQKRLILRCIAAGKPVITATQMLESMVQNPSPTRAEASDVANAIFDGTDAVMLSAETAAGAY
PVEAVAMMARIAKAVESSPEFLQKLNVLRPAPTPTTQDAIAQAADDVVEAVGARAIVVFTATGGSARRIARTRPQVPILA
LTPNPEVRNQLALVWGVYPHLAPDPQDTDDMVRIALREVKALGLAQVGDRVVIAAGVPFGVRGTTNLIRVERVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-78 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-78 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-77 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-78 45
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TTHA0003 YP_143269.1 pyruvate kinase VFG0479 Protein 4e-78 45