Gene Information

Name : TTHA0222 (TTHA0222)
Accession : YP_143488.1
Strain : Thermus thermophilus HB8
Genome accession: NC_006461
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : -
Position : 216549 - 217775 bp
Length : 1227 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGCCGGGCATCGCCATCATCGGGGCGCAGTGGGGCGACGAGGGCAAGGGCAAGGTGGTGGACGTCCTGGCCCGGGAAGC
CGACTACGTGATCCGCTACCAGGGCGGGGCCAACGCCGGCCACACCGTGGTGGCCGAGGGCAAGGTCTTCAAGCTCAACC
TCCTGCCCTCGGGGGTCATCCACCCCCACGCGGTGAACGTCCTGGGGGACGGGATGGTCATTGACCCCTTCCGCTTCCAG
GAGGAGGTGGAAGGCCTGCGGAAGGAGGGGTTTGACCCCAAGATCCTGGTCTCGGAAAGGGCCCACCTCGTCCTCCCCCA
CCACAAGCACGTGGAAAGCCGCCACAACTTCGTGGGCACCACGGGGCGCGGCATCGGTCCCGCCTACTCCGACCGGGCAA
GAAGGGTGGGGATCCGGGCTGGGGACCTTTTGGACGAGGCCACCCTGAGGGAGAGGGTGCGCCGCCTCCTCGCCGAGAAG
CCCAACTCCACCCGGGAAGCGGGCTGGGATACGGAGGAAAAGGCCCTCGCCGATCTCCACCGGATGCGGGAGATCCTAAG
CCCCTACATCGCCGACACGGGGAGCCTCCTCCGGGAGGCCTGGCGCAAGGGGAAGCGCCTCCTCTTTGAGGGGGCCCAGG
CCACCCTGCTGGACCTGAACTACGGCACCTACCCCTACGTCACGAGCTCCCATCCCACGGTGGGGGGGATCCTGGTGGGG
ACGGGCCTCTCCCACAAGGCCATCACCAAGGTCTACGGCGTGGCCAAGGCCTACACCACGAGGGTAGGGGAAGGCCCCTT
CCCCACGGAGCTCCAGGGGGAGCTCGCCCACCACCTCCGGGAAAAGGGCGGCGAGTACGGCACCACCACGGGAAGGCCCA
GGAGGGTGGGCTGGCTGGACCTGGTGGCCCTCCGGTACGCCTGCGAGGTGAACGGCTTTGACGGCCTCGTCCTCACCAAG
CTGGACGTGCTCTCCGGGCTGGAGAAGGTGAAGGTGGCCGTGGAGTACCTGGACGGGGCCCGCCCCGGGGAGGCGAGCCC
GGAGGCGGTGCGCTACTTGGAGCTTCCGGGCTGGGGCGACCTCTCCCACGTGAAGCGCCGGGAGGACCTCCCCGCAAACC
TCCTCCGCTACCTGGAGCTCGTGGAGGAGCACACCGGGGTCCCCGTGGTCCTCTTCTCCACGAGCCCCAGGCGGGAGGAC
ACCTTCGGGGCGGTGAGCTGGGTCTAA

Protein sequence :
MPGIAIIGAQWGDEGKGKVVDVLAREADYVIRYQGGANAGHTVVAEGKVFKLNLLPSGVIHPHAVNVLGDGMVIDPFRFQ
EEVEGLRKEGFDPKILVSERAHLVLPHHKHVESRHNFVGTTGRGIGPAYSDRARRVGIRAGDLLDEATLRERVRRLLAEK
PNSTREAGWDTEEKALADLHRMREILSPYIADTGSLLREAWRKGKRLLFEGAQATLLDLNYGTYPYVTSSHPTVGGILVG
TGLSHKAITKVYGVAKAYTTRVGEGPFPTELQGELAHHLREKGGEYGTTTGRPRRVGWLDLVALRYACEVNGFDGLVLTK
LDVLSGLEKVKVAVEYLDGARPGEASPEAVRYLELPGWGDLSHVKRREDLPANLLRYLELVEEHTGVPVVLFSTSPRRED
TFGAVSWV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 2e-81 46