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Name : leuS (TTHA0161) Accession : YP_143427.1 Strain : Thermus thermophilus HB8 Genome accession: NC_006461 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 155693 - 158329 bp Length : 2637 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGAGAAGTACAACCCGCACGCCATTGAGGCCAAGTGGCAGCGCTTCTGGGAGGAGAAGGGGTTCATGAAGGCCAAGGA CCTCCCGGGGGGCCGGGGGAAGCAGTACGTCCTCGTCATGTTCCCCTACCCCTCGGGGGACCTGCACATGGGCCACCTGA AGAACTACACCATGGGGGACGTCCTGGCCCGCTTCCGCCGGATGCAGGGCTACGAGGTCCTCCACCCCATGGGCTGGGAC GCTTTTGGCCTTCCGGCGGAGAACGCCGCCCTGAAGTTCGGCGTCCACCCCAAGGACTGGACCTACGAGAACATCCGCCA GGCCAAGGAGAGCCTCCGGCTCATGGGCATCCTTTACGACTGGGACCGGGAGGTCACCACCTGCGAGCCCGAGTACTACC GCTGGAACCAGTGGATCTTCCTCAAGATGTGGGAAAAGGGCCTGGCCTACCGGGCGAAGGGCCTCGTCAACTGGTGCCCC AAGTGCCAGACGGTCCTCGCCAACGAGCAGGTGGTGGAGGGGCGGTGCTGGCGGCACGAGGACACCCCCGTGGAGAAGCG GGAGCTGGAGCAGTGGTACCTGCGCATCACCGCCTACGCCGAGAGGCTTCTTAAGGACCTCGAGGGCCTCAACTGGCCCG AGAAGGTCAAGGCCATGCAAAGGGCCTGGATCGGCCGCTCCGAGGGGGCGGAGATCCTCTTCCCCGTGGAGGGGAAGGAG GTGAGGATCCCCGTCTTCACCACCCGCCCCGACACCCTCTTCGGAGCCACCTTCCTCGTGCTCGCCCCGGAGCACCCCTT GACCCTGGAGCTCGCCGCCCCGGAGAAGCGGGAGGAGGTCCTGGCCTACGTGGAGGCCGCCAAGCGCAAGACGGAGATTG AGCGCCAGGCGGAAGGCAGGGAGAAGACCGGGGTCTTCCTGGGGGCCTACGCCCTAAACCCCGCCACGGGGGAGAGGATC CCCATCTGGACCGCGGACTACGTGCTCTTTGGCTACGGCACCGGGGCCATCATGGCCGTCCCTGCCCACGACCAGAGGGA CTACGAGTTCGCCAGGAAGTTCGGCCTTCCCATCAAGAAGGTGATTGAGCGGCCCGGCGAGCCCCTCCCCGAGCCCCTGG AAAGGGCCTACGAGGAGCCCGGGATCATGGTGAACTCCGGGCCCTTTGACGGGACGGAAAGCGAGGAGGGGAAGCGGAAG GTCATCGCCTGGCTGGAGGAGAAGGGCCTGGGCAAGGGCCGGGTCACCTACCGCCTCCGGGACTGGCTCATAAGCCGCCA GCGCTACTGGGGGACCCCCATCCCCATGGTCCACTGCGAGGCCTGCGGGGTGGTCCCCGTCCCCGAGGAGGAGCTTCCCG TGCTCCTTCCCGACCTCAAGGACGTGGAGGACATCCGCCCCAAGGGGAAGAGCCCCCTGGAGGCCCACCCCGAGTTCTAC GAGACCACCTGCCCCAAGTGCGGCGGCCCCGCCAAGCGGGACACGGACACCATGGACACCTTCTTTGACTCCAGCTGGTA CTACCTGCGCTACACCGACCCCCACAACGACCGCCTCCCCTTTGACCCCGAGAAGGCGAACGCCTGGATGCCCGTGGACC AGTACATCGGCGGGGTGGAGCACGCGGTGCTTCACCTCCTCTACAGCCGCTTCTTCACCAAGTTTCTCCACGACCTGGGG ATGGTGAAGGTGGAGGAGCCCTTCCAGGGCCTCTTCACCCAGGGCATGGTCCTCGCCTGGACGGACTTTGGCCCCGTGGA GGTGGAAGGAAGCGTGGTGCGCCTCCCCGAGCCCACCCGCATCCGGCTGGAGATCCCAGAAAGCGCGCTTTCCCTGGAGA ACGTGAGGAAGATGGGGGCCGAGCTCCGCCCCCACGAGGACGGCACCCTCCACCTCTGGAAGCCCGCCGTCATGAGCAAG TCCAAGGGCAACGGGGTCATGGTGGGGCCCTTCGTGAAGGAGCAGGGGGCGGACATCGCCCGCATCACCATCCTCTTCGC CGCGCCCCCGGAGAACGAGATGGTCTGGACCGAGGAGGGGGTCCAGGGGGCCTGGCGCTTCCTGAACCGCATCTACCGGC GGGTGGCCGAGGACCGGGAGGCCCTTTTGGAGACGAGCGGGGTCTTCCAGGCCGAGGCTTTAGAGGGGAAGGACCGGGAG CTTTACGGGAAGCTGCACGAGACCCTGAAGAAGGTCACGGAGGACCTCGAGGCCCTCCGCTTCAACACCGCCATCGCCGC CCTCATGGAGTTCCTGAACGCCCTCTACGAGTACCGCAAGGACCGCCCCGTCACCCCGGTCTACCGCACCGCCATTCGCT ACTACCTGCAGATGCTCTTCCCCTTCGCCCCCCACCTCGCCGAGGAGCTTTGGCACTGGTTCTGGCCCGATAGCCTCTTT GAGGCGGGCTGGCCCGAGCTGGACGAGAAGGCCCTGGAGAAGGACGTGGTGGAGGTGGCCGTCCAGGTGAACGGGCGGGT GCGGGGGACGATCCACATCCCCAAGGACGCCCCCCTGGAGGTGGCGCGGGCCGAGGCCCTTAAGGTGCGAAACGTAAGGG CCCACCTCGAGGGCAAGGAGGTGGTGAAGGAGATCTACGTCCCGGGGAAGATCCTCAACCTGGTAGTGCGGGGGTAG Protein sequence : MEKYNPHAIEAKWQRFWEEKGFMKAKDLPGGRGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWD AFGLPAENAALKFGVHPKDWTYENIRQAKESLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCP KCQTVLANEQVVEGRCWRHEDTPVEKRELEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKE VRIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGVFLGAYALNPATGERI PIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLERAYEEPGIMVNSGPFDGTESEEGKRK VIAWLEEKGLGKGRVTYRLRDWLISRQRYWGTPIPMVHCEACGVVPVPEEELPVLLPDLKDVEDIRPKGKSPLEAHPEFY ETTCPKCGGPAKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANAWMPVDQYIGGVEHAVLHLLYSRFFTKFLHDLG MVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPESALSLENVRKMGAELRPHEDGTLHLWKPAVMSK SKGNGVMVGPFVKEQGADIARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLETSGVFQAEALEGKDRE LYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVTPVYRTAIRYYLQMLFPFAPHLAEELWHWFWPDSLF EAGWPELDEKALEKDVVEVAVQVNGRVRGTIHIPKDAPLEVARAEALKVRNVRAHLEGKEVVKEIYVPGKILNLVVRG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 6e-157 | 45 |
