Gene Information

Name : clpE (str0602)
Accession : YP_141013.1
Strain : Streptococcus thermophilus CNRZ1066
Genome accession: NC_006449
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 565361 - 567619 bp
Length : 2259 bp
Strand : -
Note : -

DNA sequence :
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAACGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACATCAACAAGCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATTTGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCTGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTACTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTACTTCACATGTTTCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGCTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATGCCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATCTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTAAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA

Protein sequence :
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGPGRPGGPHQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKDL
KAVMTSKGHITIKSAKKTEKTSQKTEALKEVN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-153 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE YP_141013.1 ATP-dependent Clp protease VFG0080 Protein 0.0 58
clpE YP_141013.1 ATP-dependent Clp protease VFG0079 Protein 4e-161 54