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Name : tkt (str0312) Accession : YP_140730.1 Strain : Streptococcus thermophilus CNRZ1066 Genome accession: NC_006449 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 294579 - 296555 bp Length : 1977 bp Strand : + Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGTCTAACCTTTCAGTAAATGCTATCCGTTTTCTAGGGGTAGATGCGATTAACCAATCTAACTCTGGCCACCCTGGTGT GGTAATGGGTGCAGCACCAATGGGTTACACTTTGTTTACTAGACAAATGCATGTCAATCCTGAAGTTCCAAATTGGATTA ATCGTGACCGTTTTGTTTTGTCAGCAGGTCATGGTTCAATGCTTCTTTATGCGCTCCTTCATTTGTCAGGATTTAAAGAT TTGAGCATTGAAGAGCTTAAACAATTCCGTCAATGGGGTTCTAAGACACCTGGTCACCCAGAATTTGGCCATACAGTTGG TGTAGATGCTACGTCAGGTCCACTTGGGCAAGGTATTGCTATGGCTGTCGGTATGGCACAAGCTGAACGTTTCTTGGCTT CTCGATACAACAAGGAAGGCTTCCCAATCTTTGACCATTATACTTATGTTATTGCGGGAGATGGTTGCTTTATGGAAGGC GTTTCGGCCGAAGCATCATCTTACGCTGGTCTTCAAAAATTGGATAAATTGATTGTCTTGTACGATTCAAATGATATCAA TCTTGACGGTGAAACTAAAGATTCATTTACTGAAGATGTACGTGCACGTTATGAAGCTTATGGTTGGAACACTGAATTTG TTCAAGATGGAACAGATATTGAAGCTATCAACGCTGCTATTGAAAGTGCAAAAGCAAGTGGTAAACCATCTTTGATTGAG GTTAAGACTGTCATTGGTCATGGTGCTCCTAATAAACAAGGAACCAACGGTGTTCACGGTGCTCCTCTTGGACCAGATGA AACAGCAGCTGCAAGAGAAAACTTGGGTTGGAACCATGCTCCATTTGAAATTCCAAAAGAAGTTTATGCTGATTTCAAGG AAAATACAGTTGATCGTGGTCGTCAGGCCTATGACACTTGGGTTGCTTTGGTAGATGAGTACAAACAATCTTACCCAGAA CTTGGTTCTGAACTTGCACGCATTCTTGAAGGTAAGGATGCAGTTGAATTCCAATCTTCAGACTTCCCAGCTGTTGAAAA TGGTTATTCACAAGCAACTCGTAATTCAAGTCAAGATGCTTTGAATGCTATTGCTGATAAAGTGCCAACATTCCTAGGTG GTTCTGCGGATTTGGCTCACTCAAATATGACTTACATTAAATCTGAAGGTCTACAAGATGATGAACATCGTCTTAACCGT AACATTCAATTTGGTGTACGTGAGTTTGCGATGGGAGCAATCTTGAATGGTATGTCTCTCCATGGTGGACTTCGTGTTTA CGGTGGTACCTTCTTCGTATTCTCAGACTATGTAAAAGCAGCAGTTCGTTTGTCTGCACTTCAAGGACTTCCAGTTACTT ATGTCTTTACTCACGACTCTATTGCAGTTGGTGAAGATGGACCAACCCATGAACCAATCGAACATCTAGCTGGACTTCGT GCTATTCCAAACCTTAATGTTTATCGTCCAGCAGACGCGCGTGAGACACAGGCTGCATGGTATCAAGCTATAACTTCTAA ATCAACACCTACGGCGCTTGTTTTGACACGTCAAAACTTGACTGTTGAAGAAGGAACAGATTTTGATAAAGTTTCAAGAG GTGCTTACGTTGTTCATGAAACAGCAGCAGATTTTGATACTATTCTCCTTGCTTCTGGTTCAGAAGTAAATCTTGCAGTA GCATCAGCAAAAGCTTTGGAATCAGAAGGTTATAAAGTTCGTGTTGTGAGTGTTCCATCAACAGATGTCTTTGATGCACA AGATCAAGCCTACAAAGAGGAAGTTCTTCCAAATGCAGTTCGTCGTCGTGTAGCAATCGAAATGGCAGCAAGTCTACCAT GGTATAAATATGTTGGTTTAGACGGTGCTGTGATTGGAATTGATACATTTGGTGCCTCAGCTCCAGCTGCTAAAATTATT GAAGAATATGGCTTTACAGTAGAAAATATCGTTGAAACAGTAAAAGGTATGAACTAA Protein sequence : MSNLSVNAIRFLGVDAINQSNSGHPGVVMGAAPMGYTLFTRQMHVNPEVPNWINRDRFVLSAGHGSMLLYALLHLSGFKD LSIEELKQFRQWGSKTPGHPEFGHTVGVDATSGPLGQGIAMAVGMAQAERFLASRYNKEGFPIFDHYTYVIAGDGCFMEG VSAEASSYAGLQKLDKLIVLYDSNDINLDGETKDSFTEDVRARYEAYGWNTEFVQDGTDIEAINAAIESAKASGKPSLIE VKTVIGHGAPNKQGTNGVHGAPLGPDETAAARENLGWNHAPFEIPKEVYADFKENTVDRGRQAYDTWVALVDEYKQSYPE LGSELARILEGKDAVEFQSSDFPAVENGYSQATRNSSQDALNAIADKVPTFLGGSADLAHSNMTYIKSEGLQDDEHRLNR NIQFGVREFAMGAILNGMSLHGGLRVYGGTFFVFSDYVKAAVRLSALQGLPVTYVFTHDSIAVGEDGPTHEPIEHLAGLR AIPNLNVYRPADARETQAAWYQAITSKSTPTALVLTRQNLTVEEGTDFDKVSRGAYVVHETAADFDTILLASGSEVNLAV ASAKALESEGYKVRVVSVPSTDVFDAQDQAYKEEVLPNAVRRRVAIEMAASLPWYKYVGLDGAVIGIDTFGASAPAAKII EEYGFTVENIVETVKGMN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 2e-152 | 49 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 5e-150 | 48 |
