Gene Information

Name : polA (str1761)
Accession : YP_142094.1
Strain : Streptococcus thermophilus CNRZ1066
Genome accession: NC_006449
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 1572077 - 1574716 bp
Length : 2640 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGACTAATCAAAAAAAATTACTATTAATCGACGGTTCGTCCGTTGCCTTTCGTGCTTTTTTCGCACTCTATAATCAAAT
TGACCGTTTTCGTAACAATAACGGCCTTCATACCAATGCCATCTACGGCTTTCACCTTATGTTGGACAACCTACTTGAGC
GTATTCAGCCGACCCATGTCTTAGTAGCTTTTGATGCGGGAAAAACAACTTTTCGTACAGAGATGTTTGCGGACTATAAG
GCTGGTCGTGCCAAGACTCCAGAGGAATTCCGTGAACAGCTCCCTTATATCCGTGAGATGTTGGCTGCACGTGGCATTGC
CTATTATGACTTGGCTCAGTACGAGGCAGATGACATTATCGGTACCTTAGCTAAGATGGCTGAAAATACTAGTGAGGCCT
TTCAAATTACTGTTGTTTCTGGGGATAAAGACTTGATTCAGCTGACTGATGAAAATACAGTCGTTGAGATTTCGAAGAAA
GGCGTAGCTGAGTTTGAGGCCTTCACTCCTGACTATCTCATGGAGAAAATGGGGATTACTCCAGCTCAATTCGTCGATCT
TAAGGCCCTCATGGGTGACAAGTCCGACAATATTCCAGGGGTTACTAAGATAGGTGAAAAGACTGGTCTCAAGCTCCTCT
TGGAACACGGTTCCCTTGAAGGCATCTATGACCACATTGATGAGATGAAAAAGTCCAAAATGAAGGAAAATCTCATCAAC
GACAAGGAACAAGCCTTCCTTTCTAAGACCTTGGCGACCATTGATACACAGTCACCTATTGAAATTGGCCTAGATGATAC
GGCCTTTAAGGGACCTAACCTTGAAAAATTGCTAGCCTTTTATGACGAGATGGGCTTTGTTCATTTCAAAAATGCTCTTC
GCGGAGAGGCTGTCCCACAGGATTTTGATGTGGCCTATGTAGAGCCTAGCCAAGTGACAGCGGATCACTTTAGCTCTGAA
GATTTCTTCTATTTTGAAATCCTCGGTGACAATTATCACACAGAACCTATCATCGGTTTTGCTTGGGGAAATGAAAAGCA
GATTTATGCGTCTACAGATACTGACCTACTCAAATCAGAAGCATTCCAAGCAGCTCTTTCTAAGGCTGTTAATATCTACG
ATTTCAAGCGCAGTAAGGTCCTTTTGAGCCATCTAGGTATTGACTTGCCGACAGCTAATTTTGATGCCCGTTTAGCCAAG
TATTTGCTCTCAACTGTTGAGGACAATGAATTGTCAACCATTGCTCGTCTCTACACAGATTTACCACTGGAAACAGATGA
GGTGGTCTATGGTAAGGGAGCTAAGCGTGCCATTCCTGAAAAAGAGGTCTTGCTCAGCCACCTGGCTAAAAAAGTCAAGG
TCCTTCAGGTTGCCAAACCGGTCATGCTAGAAAAGTTAGCTGAACATGGCCAATCAGAGCTTCTCTTTGACATGGAATTA
CCATTGGCAAATGTGTTAGCCAAGATGGAAATGGCTGGTATTAAGGTCGATGGACAAACCCTTAACGAGATGGCAGTGGA
AAACCAAGCAGTCATCGACAAATTGACCCAAGACATCTACGAAATGGCGGGCGAAGAATTCAATATTAACTCGCCTAAAC
AGTTGGGTGTTATCCTCTTTGAAAAAATGGGTCTACCTTTGGAATACACTAAGAAAACCAAGACAGGTTATTCAACGGCA
GTGGATGTCCTTGAACGTTTGGCACCAATTGCTCCAATAGTAGCTAAGATTTTAGAGTACCGCCAAATCACTAAGCTTCA
GTCTACCTATGTCTTGGGGCTTCAGGATTATATCCTTGAGGATGGTAAGATCCATACCCGTTACATGCAAGATTTGACCC
AGACAGGTCGACTCTCATCTGTGGATCCTAACTTGCAAAATATCCCCGTTCGCTTGGAGCAGGGTCGTCTCATCCGTAAG
GCCTTTGTCCCATCGACTAAGGACGCGGTGCTACTAAGCTCGGATTACTCACAAATTGAGTTGCGCGTGCTTGCCCACAT
TTCGGGAGATGAGCATTTGATTGCAGCCTTTAAGGAGGGGGCGGATATCCATACCTCTACAGCCATGCGTGTCTTTGGTA
TTGAAAAGCCAGAGGATGTCACACCTAACGACCGTCGTAACGCTAAGGCTGTTAACTTCGGTATCGTTTATGGTATTTCT
GACTTTGGTCTTTCTAACAACCTTGGTATTAGCCGTAAGAAGGCCAAGGAGTATATTGACACCTATTTTGAGCGTTATCC
TGGTATTAAGGCTTATATGGATAATGTGGTTCGTGAAGCCAAGAATAAAGGATATGTATCAACCCTCTTCCACCGCCGTC
GTGAGTTACCAGATATCAATTCTCGTAACTTTAATGTCCGTAACTTCGCAGAGCGAACAGCCATAAACTCTCCTATCCAA
GGAAGTGCTGCTGATATCCTCAAGATTGCTATGATTAACTTAGACAAGGCTCTGGTAGAAGGTGGCTATAAAACCAAGAT
GCTCCTCCAAGTACACGATGAAATCATCCTTGAGGTGCCAAGAGACGAACTTTTAGCTATGAAAGCTTTGGTTAAAGAAA
CCATGGAAGCTGCAGTAGAACTCGCTGTCCCACTCATCGCAGATGAAAATGAGGGCTGTACATGGTATGAGGCAAAGTAA

Protein sequence :
MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHVLVAFDAGKTTFRTEMFADYK
AGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDIIGTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKK
GVAEFEAFTPDYLMEKMGITPAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN
DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRGEAVPQDFDVAYVEPSQVTADHFSSE
DFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKSEAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAK
YLLSTVEDNELSTIARLYTDLPLETDEVVYGKGAKRAIPEKEVLLSHLAKKVKVLQVAKPVMLEKLAEHGQSELLFDMEL
PLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVILFEKMGLPLEYTKKTKTGYSTA
VDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYILEDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRK
AFVPSTKDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGIS
DFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKNKGYVSTLFHRRRELPDINSRNFNVRNFAERTAINSPIQ
GSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIILEVPRDELLAMKALVKETMEAAVELAVPLIADENEGCTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 78