Gene Information

Name : secA (str1730)
Accession : YP_142063.1
Strain : Streptococcus thermophilus CNRZ1066
Genome accession: NC_006449
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1544773 - 1547322 bp
Length : 2550 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCAAATATATTACGCAAAATCATTGAAAATGATAAGGGCGAAATTAAAAAACTAGAAAAAACTGCCAAGAAAGTTGA
GAGCTATGCTGATGCAATGGCGGCTCTTTCAGATGAAGAACTTCAGGCAAAAACAGAAGAATTTAAACAACGATATCAAA
ACGGAGAAAGTCTAGATCAGCTCTTGCCGGAGGCATTTGCGGTTGTTCGTGAGGGAGCGAAACGTGTCCTTGGACTTTTC
CCATATCGTGTGCAAATTATGGGTGGTATTGTGCTTCACCATGGTGACGTAGCGGAGATGCGTACAGGGGAAGGGAAAAC
CCTTACTGCGACAATGCCTGTCTACTTGAATGCTATTTCAGGTGAAGGTGTACACGTTATCACCGTTAACGAATACCTTT
CAGAGCGTGATGCGACTGAAATGGGTGAGCTTTATAGTTGGCTCGGTTTGTCAGTAGGGATCAACCTTTCATCTAAATCA
CCAGCTGAAAAACGTGAAGCTTATAATTGTGACATCACTTACTCAACCAGCTCAGAGGTAGGTTTCGACTATCTTCGTGA
TAATATGGTTGTTCGTAAGGAAAACATGGTACAACGCCCATTGAACTTTGCCTTGGTCGATGAGGTTGACTCGGTTCTTA
TTGATGAAGCTCGTACACCATTGATCGTATCAGGGCCTGTAAGTTCAGAAACTAATCAGTTGTATCACCGTGCGGATGCT
TTTGTTAAGACATTGACTGAAGATGATTATGCGATTGATATTCCAACAAAAACAATTGGTTTGAATGACTCAGGTATTGA
CAAGGCTGAAGAGTTCTTCAACTTGGAAAATTTGTACGATATTGACAATGTTGCCTTGACTCACTATATTGACAATGCCC
TTCGTGCCAACTACATTATGTTGCGTGATATTGACTACGTGGTAAGTCCTGAGCAAGAAATCCTTATTGTTGACCAGTTT
ACTGGTCGTACCATGGAAGGTCGTCGTTTTTCAGATGGGCTCCACCAAGCCATTGAGGCTAAAGAAGGTGTACCAGTCCA
AGAGGAAACCAAGACTTCTGCCTCAATCACTTACCAAAATATGTTCCGTATGTACAAGAAATTGTCAGGTATGACTGGTA
CTGGTAAGACTGAAGAGGATGAATTCCGTGAAATCTATAACATGCGAGTCATCCCAATTCCAACAAACCGTCCAATTCAA
CGTATTGACCATGATGACCTTCTGTACTCAACTTTGGATGCTAAATTCCGTGCTGTGGTACAAGATGTTAAGCGTCGTTA
TGATAAGGGGCAACCAGTTCTTATTGGTACGGTTGCCGTTGAAACATCTGACTTGATTTCTAAGATGTTGGTTGACGCAG
GTATTCCTCACGAAGTACTTAATGCCAAGAACCACGAAAAAGAAGCGCATATTATCATGAATGCAGGTCAACGTGGTGCT
GTTACGATTGCGACCAATATGGCCGGTCGTGGTACTGACATCAAACTTGGTGAAGGTGTTCTGGAGCTTGGTGGACTTTG
TGTCATTGGTACAGAGCGTCATGAAAGTCGTCGTATCGACAACCAGTTGCGTGGTCGTTCGGGACGTCAAGGGGATCCAG
GGGAGTCTCAATTCTACCTATCTCTTGAAGACGAATTGATGCGTCGTTTCGGTTCTGACCGTATCAAGCATGTCTTGGAA
CGTTTGAACGCTGATGACGAAGATATTGTTATCAAATCACGTATGTTGACTCGTCAAGTGGAATCAGCTCAAAAACGTGT
CGAAGGGAATAACTACGATACTCGTAAACAAGTCCTTCAGTACGATGACGTTATGCGTGAACAGCGTGAAATCATCTACG
CTGAGCGTTATGATGTTATTACAGCAGAACGTGACCTTGAACCTGAAATCAAGGCTATGATCAAGCGTACTATTAACCGT
ACGGTTGATGGACACAGTCGTAACGATCAAGAAGAAGCTCTTAAAGGTATCTTGAACTTTGCACGTCAGGCCTTGGTTCC
TGAGGATGCCATCTCGCTTGAAGATCTAAAAGAAGTGGGAGAGGTGACTAAACGTAGTGTTAATTATGATGCTATCAAGG
TTTATCTGACTGAGTTAGCAGATAATGTTTATGATCGTCAAATTAAGAAATTGCGTTCAGAGGAGGCTATTCGCGAATTC
CAAAAAGTCTTGATTTTGATGGTTGTTGATAATAAGTGGACAGACCACATTGATGCCCTTGATCAATTACGTAACGCCGT
TGGTATGCGTGGTTATGCGCAAAACAACCCAATCGTTGAGTATCAATCTGAAAGTTTCAAGATGTTCCAAGATATGATTG
GTGCTATTGAGTATGATGTAACTCGTACGATGATGAAAGCACAAATCCACGAACAATCTCGTGAACATGTTAATGAACGT
GTTTCAACAACAGCAACAGGCAATATTCAAGCACATCAAGCAGATGCTAACGGTCAAGAGATTGACTTTAGCAAGGTTGG
TCGTAATGACTTCTGTCCATGTGGCTCTGGTAAGAAATTCAAAAATTGTCACGGTCGTAAACAGTTTTAG

Protein sequence :
MANILRKIIENDKGEIKKLEKTAKKVESYADAMAALSDEELQAKTEEFKQRYQNGESLDQLLPEAFAVVREGAKRVLGLF
PYRVQIMGGIVLHHGDVAEMRTGEGKTLTATMPVYLNAISGEGVHVITVNEYLSERDATEMGELYSWLGLSVGINLSSKS
PAEKREAYNCDITYSTSSEVGFDYLRDNMVVRKENMVQRPLNFALVDEVDSVLIDEARTPLIVSGPVSSETNQLYHRADA
FVKTLTEDDYAIDIPTKTIGLNDSGIDKAEEFFNLENLYDIDNVALTHYIDNALRANYIMLRDIDYVVSPEQEILIVDQF
TGRTMEGRRFSDGLHQAIEAKEGVPVQEETKTSASITYQNMFRMYKKLSGMTGTGKTEEDEFREIYNMRVIPIPTNRPIQ
RIDHDDLLYSTLDAKFRAVVQDVKRRYDKGQPVLIGTVAVETSDLISKMLVDAGIPHEVLNAKNHEKEAHIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVLELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGSDRIKHVLE
RLNADDEDIVIKSRMLTRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAERYDVITAERDLEPEIKAMIKRTINR
TVDGHSRNDQEEALKGILNFARQALVPEDAISLEDLKEVGEVTKRSVNYDAIKVYLTELADNVYDRQIKKLRSEEAIREF
QKVLILMVVDNKWTDHIDALDQLRNAVGMRGYAQNNPIVEYQSESFKMFQDMIGAIEYDVTRTMMKAQIHEQSREHVNER
VSTTATGNIQAHQADANGQEIDFSKVGRNDFCPCGSGKKFKNCHGRKQF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 1e-140 41