Gene Information

Name : metB1 (stu0352)
Accession : YP_138887.1
Strain : Streptococcus thermophilus LMG 18311
Genome accession: NC_006448
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 342893 - 343987 bp
Length : 1095 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACACAAGATTATCAATTAGAAACTATTTTGGCACATGCAGGAATCAATTCTGATGAAGCAACAGGAGCTTTAGCTTC
ACCGATTCATTTTTCAACAACTTACCAACATCCAGAATTCGGACAGTCTACTGGTTTTGACTATACACGAACTAAAAATC
CAACGCGTGCAACAGTGGAAAAAACGCTAGCAGCTATTGAAAAAGCGGATTATGCTATTGCGACAAGTTCAGGAATGAGC
GCTATTGTTTTGGCCTTTGAAATTTTCCCTGTAGGTAGCAAGGTTGTCGCTGCCCGTGACCTTTATGGAGGTTCTTTCCG
TTGGTTCAACGATAAAGAAAAAGAAGGACGTTTCTTCTTTGAATACACCAATACAGAAGATGAGATGATTGCGGCTATTG
CAGAAGATACCGATATTGTCTACATTGAAACACCGACAAACCCACTTATGATTGAGTTTGATATTGAGAAAGTAGCTCAG
ACTGCCCATGAAAAGGGTGCGGTGGTTATTGTTGATAATACCTTCTATAGCCCAATCTACCAAACCCCGATTACTCAAGG
TGCTGATATCGTTGTACATTCAGCTACTAAATACCTATCAGGGCATAATGATGTTTTAGCTGGTGTTGTTGTGACTAGCA
ATCCAGAATTCTACGATAAACTTTATTATAACCTCAATACGACTGGTCCGAACTTGTCCCCATTTGATAGCTATATGCTC
ATGCGTGGACTTAAGACCCTAAAACTTCGTATGGAGGCATCAACGGCTAATGCTAAAGAAGTTGTGGCGTTCTTAGAAAA
GTCCCCAGCTGTTAAAGAGGTTCTCTACCCAGGTAAGGGTGGGATGATTTCCTTCAAAGTGGCTAACCAAGATAAGATTC
CAACTATTATCAATACTCTTAAGGTCTTTACCTTTGCGGAGAGTCTGGGTGGTGTTGAAAGTTTGATTACTTACCCAGCA
ACACAAACTCACGCAGATATTCCAAGTGAAGTACGTGCCTCGTATGGATTAACGGATGACTTGCTTCGTCTTTCAATTGG
TATTGAAGCAGCAGAGGATTTAATTGCTGACTTGGAAAATGCCCTTAGTCTTTAA

Protein sequence :
MTQDYQLETILAHAGINSDEATGALASPIHFSTTYQHPEFGQSTGFDYTRTKNPTRATVEKTLAAIEKADYAIATSSGMS
AIVLAFEIFPVGSKVVAARDLYGGSFRWFNDKEKEGRFFFEYTNTEDEMIAAIAEDTDIVYIETPTNPLMIEFDIEKVAQ
TAHEKGAVVIVDNTFYSPIYQTPITQGADIVVHSATKYLSGHNDVLAGVVVTSNPEFYDKLYYNLNTTGPNLSPFDSYML
MRGLKTLKLRMEASTANAKEVVAFLEKSPAVKEVLYPGKGGMISFKVANQDKIPTIINTLKVFTFAESLGGVESLITYPA
TQTHADIPSEVRASYGLTDDLLRLSIGIEAAEDLIADLENALSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-62 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-61 42