Gene Information

Name : polA (stu1761)
Accession : YP_140175.1
Strain : Streptococcus thermophilus LMG 18311
Genome accession: NC_006448
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 1568515 - 1571154 bp
Length : 2640 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGACTAATCAAAAAAAATTACTATTAATCGACGGTTCGTCCGTTGCCTTTCGTGCTTTTTTCGCACTCTATAATCAAAT
TGACCGTTTTCGTAACAATAACGGCCTTCATACCAATGCCATTTACGGCTTTCACCTTATGTTGGACAACCTACTTGAGC
GTATTCAGCCGACCCATGTCTTAGTAGCTTTTGATGCGGGAAAAACAACTTTTCGTACAGAGATGTTTGCGGACTATAAG
GCTGGTCGTGCCAAGACTCCAGAGGAATTCCGTGAACAGCTCCCTTATATCCGTGAGATGTTGGCTGCACGTGGCATTGC
CTATTATGACTTGGCTCAGTACGAAGCAGATGACATTATCGGTACCTTAGCTAAGATGGCTGAAAATACTAGTGAGGCCT
TTCAAATTACTGTTGTTTCTGGGGATAAAGACTTGATTCAGCTGACTGATGAAAATACAGTCGTTGAGATTTCGAAGAAA
GGCGTAGCTGAGTTTGAGGCCTTCACTCCTGACTATCTCATGGAGAAAATGGGGATTACTCCAGCTCAATTCGTCGATCT
TAAGGCCCTCATGGGTGACAAGTCCGACAATATTCCAGGGGTTACTAAGATAGGTGAAAAGACTGGTCTCAAGCTCCTCT
TGGAACACGGTTCCCTTGAAGGCATCTATGACCACATTGATGAGATGAAAAAGTCCAAAATGAAGGAAAATCTCATCAAC
GACAAGGAACAAGCCTTCCTTTCTAAGACCTTGGCGACCATTGATACACAGTCACCTATTGAAATTGGCCTAGATGATAC
GGCCTTTAAGGGACCTAACCTTGAAAAATTGCTAGCCTTTTATGACGAGATGGGCTTTGTTCATTTCAAAAATGCTCTTC
GCGGAGAGGCTGTCCCACAGGATTTTGATGTGGCCTATGTAGAGCCTAGCCAAGTGACAGCGGATCACTTTAGCTCTGAA
GATTTCTTCTATTTTGAAATCCTCGGTGACAATTATCACACAGAACCTATCATCGGTTTTGCTTGGGGAAATGAAAAGCA
GATTTATGCGTCTACAGATACTGACCTACTCAAATCAGAAGCATTCCAAGCAGCTCTTTCTAAGGCTGTTAATATCTACG
ATTTCAAGCGCAGTAAGGTCCTTTTGAGCCATCTAGGTATTGACTTGCCGACAGCTAATTTTGATGCCCGTTTGGCCAAG
TATTTGCTCTCAACTGTTGAGGACAATGAATTGTCAACCATTGCTCGTCTCTACACAGATTTACCACTGGAAACAGATGA
GGTGGTCTATGGTAAGGGAGCTAAGCGTGCCATTCCTGAAAAAGAGGTCTTGCTCAGCCACCTGGCAAAAAAAGTCAAGG
TCCTTCAGGTTGCCAAACCGGTCATGCTAGAAAAGTTAGCTGAACATGGCCAATCAGAGCTTCTCTTTGACATGGAATTA
CCATTGGCAAATGTGTTAGCCAAGATGGAAATGGCTGGTATTAAGGTTGATGGACAAACCCTTAACGAGATGGCAGTGGA
AAACCAAGCAGTCATCGACAAATTGACCCAAGACATCTACGAAATGGCGGGCGAAGAATTCAATATTAACTCGCCTAAAC
AGTTGGGTGTTATCCTCTTTGAAAAAATGGGTCTACCTTTGGAATACACTAAGAAAACCAAGACAGGTTATTCAACGGCA
GTGGATGTCCTTGAACGTTTGGCACCAATTGCTCCAATAGTAGCTAAGATTTTAGAGTACCGCCAAATCACTAAGCTTCA
GTCTACCTATGTCTTGGGGCTTCAGGATTATATCCTTGAGGATGGTAAGATCCATACCCGTTACATGCAAGATTTGACCC
AGACAGGTCGACTCTCATCTGTGGATCCTAACTTGCAAAATATTCCCGTTCGCTTGGAGCAGGGTCGTCTCATCCGTAAG
GCCTTTGTCCCATCGACTAAAGACGCAGTGCTACTAAGCTCGGATTACTCACAAATTGAGTTGCGCGTGCTTGCCCACAT
TTCGGGAGATGAGCATTTGATTGCAGCCTTTAAGGAGGGGGCGGATATCCATACCTCTACAGCCATGCGTGTCTTTGGTA
TTGAAAAGCCAGAGGATGTCACACCTAACGACCGTCGTAACGCTAAGGCTGTTAACTTCGGTATCGTTTATGGTATTTCT
GACTTTGGTCTTTCTAACAACCTTGGTATTAGCCGTAAGAAGGCCAAGGAGTATATTGACACCTATTTTGAGCGTTATCC
TGGTATTAAGGCTTATATGGATAATGTGGTTCGTGAAGCCAAGGATAAAGGATATGTATCAACCCTCTTCCACCGCCGTC
GTGAGTTACCAGATATCAATTCTCGTAACTTTAATGTCCGTAACTTCGCAGAGCGAACAGCCATAAACTCTCCTATCCAA
GGAAGTGCTGCTGATATCCTCAAGATTGCTATGATTAACTTAGACAAGGCTCTGGTAGAAGGTGGCTATAAAACCAAGAT
GCTCCTCCAAGTACACGATGAAATCATCCTTGAGGTGCCAAGAGACGAACTTTTAGCTATGAAAGCTTTGGTTAAAGAAA
CCATGGAAGATGCAGTAGAACTCGCTGTCCCACTCATCGCAGATGAAAATGAGGGCTGTACATGGTATGAGGCAAAGTAA

Protein sequence :
MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHVLVAFDAGKTTFRTEMFADYK
AGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDIIGTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKK
GVAEFEAFTPDYLMEKMGITPAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN
DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRGEAVPQDFDVAYVEPSQVTADHFSSE
DFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKSEAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAK
YLLSTVEDNELSTIARLYTDLPLETDEVVYGKGAKRAIPEKEVLLSHLAKKVKVLQVAKPVMLEKLAEHGQSELLFDMEL
PLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVILFEKMGLPLEYTKKTKTGYSTA
VDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYILEDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRK
AFVPSTKDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGIS
DFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGYVSTLFHRRRELPDINSRNFNVRNFAERTAINSPIQ
GSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIILEVPRDELLAMKALVKETMEDAVELAVPLIADENEGCTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 78